Between (Racial) Groups and a Hard Place: An Exploration of Social Science Approaches to Race and Genetics, 2000-2014 [0.03%]
种族群体夹缝中:社会科学研究中的种族与遗传学(2000-2014)
W Carson Byrd,Latrica E Best
W Carson Byrd
As the social sciences expand their involvement in genetic and genomic research, more information is needed to understand how theoretical concepts are applied to genetic data found in social surveys. Given the layers of complexity of studyi...
Validation of an Optimized ELISA for Quantitative Assessment of Epstein-Barr Virus Antibodies from Dried Blood Spots [0.03%]
优化定量测定干血斑中爱泼斯坦-巴尔病毒抗体的酶联免疫吸附测定方法的验证
Geeta Eick,Samuel S Urlacher,Thomas W McDade et al.
Geeta Eick et al.
Our objective was to validate a commercially available ELISA to measure antibody titers against Epstein-Barr virus (EBV) in dried blood spots (DBS) to replace a previously validated assay for DBS that is no longer available. We evaluated th...
Population Distributions of Thymic Function in Adults: Variation by Sociodemographic Characteristics and Health Status [0.03%]
成人胸腺功能的人口分布:不同社会人口统计学特征和健康状况的差异性分析
Lydia Feinstein,Sara Ferrando-Martínez,Manuel Leal et al.
Lydia Feinstein et al.
The thymus is critical for mounting an effective immune response and maintaining health. However, epidemiologic studies characterizing thymic function in the population setting are lacking. Using data from 263 adults in the Detroit Neighbor...
Clostridium difficile Infection: An Emerging Cause of Death in the Twenty-First Century [0.03%]
二十一世纪难辨梭菌感染的流行导致死亡率上升
Viytta N Abdullatif,Andrew Noymer
Viytta N Abdullatif
Enterocolitis due to Clostridium difficile is major emerging cause of death in the U.S. Between 1999 and 2012, C. diff. deaths rose by a staggering almost ten-fold amount, to 7,739 from 793. This article has three goals. First, we present a...
Genome-Wide Profiling of RNA from Dried Blood Spots: Convergence with Bioinformatic Results Derived from Whole Venous Blood and Peripheral Blood Mononuclear Cells [0.03%]
来源于干血滴纸片的全基因组RNA谱分析及其与静脉血和外周血单个核细胞 bioinformatic结果的一致性研究
Thomas W McDade,Kharah M Ross,Ruby L Fried et al.
Thomas W McDade et al.
Genome-wide transcriptional profiling has emerged as a powerful tool for analyzing biological mechanisms underlying social gradients in health, but utilization in population-based studies has been hampered by logistical constraints and cost...
An Old Mom Keeps You Young: Mother's Age at Last Birth and Offspring Longevity in Nineteenth-Century Utah [0.03%]
老妈养你久——19世纪犹他州母亲高龄生产与子女长寿的关系
Saskia Hin,Bartosz Ogórek,Finn Hedefalk
Saskia Hin
This study analyzes the intergenerational effects of late childbearing on offspring's adult longevity in a population in Utah (United States) that does not display evidence of parity-specific birth control-a so-called natural fertility popu...
The Changing Body Mass-Mortality Association in the United States: Evidence of Sex-Specific Cohort Trends from Three National Health and Nutrition Examination Surveys [0.03%]
基于三次全美健康与营养调查的证据:美国体重-死亡率关系的变化及性别差异
Yan Yu
Yan Yu
The association between body mass index (BMI) categories and mortality remains uncertain. Using three National Health and Nutrition Examination Surveys covering the 1971-2006 period for cohorts born between 1896 and 1968, this study estimat...
The Geographic Distribution of Genetic Risk as Compared to Social Risk for Chronic Diseases in the United States [0.03%]
美国慢性病的遗传风险与社会风险的地域分布比较
David H Rehkopf,Benjamin W Domingue,Mark R Cullen
David H Rehkopf
There is an association between chronic disease and geography, and there is evidence that the environment plays a critical role in this relationship. Yet at the same time, there is known to be substantial geographic variation by ancestry ac...
Differential Vulnerability to Early-Life Parental Death: The Moderating Effects of Family Suicide History on Risks for Major Depression and Substance Abuse in Later Life [0.03%]
童年丧亲导致重性抑郁和物质使用障碍的高危效应:自杀家族史的调节作用
Michael S Hollingshaus,Hilary Coon,Sheila E Crowell et al.
Michael S Hollingshaus et al.
Only a portion of those individuals exposed to parental death in early life (PDE) develop behavioral health disorders. We utilized demographic pedigree data from the Utah Population Database to test for differential vulnerability to PDE by ...
Neighborhood and Family Environment of Expectant Mothers May Influence Prenatal Programming of Adult Cancer Risk: Discussion and an Illustrative DNA Methylation Example [0.03%]
母亲的邻里和家庭环境可能会影响胎儿癌症风险的发育起源:讨论及一个表观遗传修饰实例的说明
Katherine E King,Jennifer B Kane,Peter Scarbrough et al.
Katherine E King et al.
Childhood stressors including physical abuse predict adult cancer risk. Prior research portrays this finding as an indirect mechanism that operates through coping behaviors, including adult smoking, or through increased toxic exposures duri...