In Situ Phase-Transited Asymmetric Membrane Capsules: A Means for Achieving Delayed and Osmotic Release for pH Solubility-Dependant Drugs [0.03%]
原位相变不对称囊泡胶囊：pH溶解度依赖型药物的缓释及渗透压促释输送体系
Anil K Philip,Betty Philip
Anil K Philip
In the present study, an in situ nondisintegrating polymeric capsular system in achieving delayed as well as improved osmotic flow for the model drug cefadroxil was developed. In situ formed asymmetric membrane capsule was prepared by preci...
Formulation development of ambroxol hydrochloride soft gel with application of statistical experimental design and response surface methodology [0.03%]
响应面法结合统计实验设计应用于盐酸氨溴索软胶囊处方研究
Mahesh Dabhi,Mukesh Gohel,Rajesh Parikh et al.
Mahesh Dabhi et al.
The purpose of present work was to develop ambroxol hydrochloride soft gel formulation with the application of statistical experimental design and response surface methodology (RSM). A two-factor, three-level (3(2)) full factorial design of...
Formulation and characterization of an expandable, gastroretentive system of carvedilol phosphate by 32 factorial design [0.03%]
采用32因素实验设计法制定和表征卡维地洛磷酸盐的可膨胀胃滞留体系
Amelia M Avachat,Kiran B Patel,Mohanish S Rokade et al.
Amelia M Avachat et al.
A 3(2) full factorial design was employed for the formulation and characterization of an expandable, gastroretentive sustained-release formulation of carvedilol phosphate to maintain drug levels within a desired range, reduce dosing frequen...
Applications of Headspace Moisture Analysis for Investigating the Water Dynamics within a Sealed Vial Containing Freeze-dried Material [0.03%]
顶空水分分析在探究密封安瓿瓶中冻干材料内水分动态方面的应用研究
Isobel Ann Cook,Kevin Richard Ward
Isobel Ann Cook
We compare frequency modulation spectroscopy (FMS) as a method of headspace water analysis with the method of Karl Fischer coulometric titration (KF), which is widely used in the analysis of residual water in a freeze-dried material. Parame...
Chris Watts,Kurt Brorson
Chris Watts
Nitrogen Dioxide Sterilization is a New State-of-the-Art Sterilization Technology to Control Contamination Risks From Your Prefilled Devices and Combination Drug Products [0.03%]
用于预装药物装置和组合型药物产品的新型灭菌技术——二氧化氮 sterilization 可有效控制污染风险
Prefilled Devices and Combination Drug Products, particularly those with integrated fluid paths or for specific Therapeutic Areas like Ophthalmology, may require final sterilization. Nitrogen Dioxide is a ground breaking novel sterilization...