Jennifer Herring,Maureen McMichael
Jennifer Herring
A well-designed and executed diagnostic approach to patients with bleeding disorders is critical to determine disease etiology and guide therapeutic measures. This systematic process begins with a comprehensive history and physical examinat...
Update on disseminated intravascular coagulation: when to consider it, when to expect it, when to treat it [0.03%]
弥漫性血管内凝血的进展:何时考虑、何时预期以及何时治疗
Alan G Ralph,Benjamin M Brainard
Alan G Ralph
Disseminated intravascular coagulation (DIC) spans a continuum in which clinical signs can range from a prothrombotic to a hemorrhagic phenotype, with some patients suffering from both concurrently. DIC is always caused by an underlying con...
Armelle de Laforcade
Armelle de Laforcade
Coagulation abnormalities are commonly encountered in critical illness. Traditionally, clinically relevant coagulation disorders have consisted mostly of bleeding associated with advanced stages of disseminated intravascular coagulation or ...
James W Barr,Maureen McMichael
James W Barr
Inherited disorders of hemostasis encompass abnormalities in primary hemostasis, coagulation, and fibrinolysis resulting from genetic mutations. There is significant variation in the phenotype expressed ranging from life limiting to the abs...
Mauria OBrien
Mauria OBrien
Inflammation and coagulation constitute two host defense systems with complementary roles in eliminating invading pathogens, limiting tissue damage, and restoring homeostasis. Extensive cross talk exists between these 2 systems, whereby inf...
New models of hemostasis [0.03%]
新的止血模型
Maureen McMichael
Maureen McMichael
Hemostasis is an essential protective mechanism that depends on a delicate balance of procoagulant and anticoagulant processes. The waterfall/cascade models of coagulation are useful for understanding several essential steps of coagulation ...
Maureen McMichael
Maureen McMichael
Marta Planellas,Núria Martin,Carles Pons et al.
Marta Planellas et al.
This short communication describes the diagnosis, treatment, and clinical course of a domestic short-haired cat with diaphragmatic hernia in which the herniated structure in the thoracic cavity contained a mummified fetus. The cat was pregn...
Feline acromegaly [0.03%]
猫的肢端肥大症
Deborah S Greco
Deborah S Greco
Acromegaly, or hypersomatotropism, results from chronic, excessive secretion of growth hormone in the adult animal. The anabolic effects of growth hormone are exerted through the intermediary hormone, insulin-like growth factor 1, which is ...
Medical management of pituitary-dependent hyperadrenocorticism: mitotane versus trilostane [0.03%]
库欣病的医疗管理:美替拉酮与曲洛司坦
Nyssa J Reine
Nyssa J Reine
Pituitary-dependent hyperadrenocorticism is a common endocrine disorder in dogs in the United States. Once a diagnosis is established, a decision must be made whether or not to pursue treatment, and if so, which medication to use. Historica...