Synthesis and Characterization of MIP Ghost Approach for Selective Extraction of Empagliflozin and Quantification by Liquid Chromatography [0.03%]
用于选择性提取恩格列净的MIP鬼方法的合成与表征及液相色谱测定法量化研究
Durga Panikumar Anumolu,Jampana Ramatulasi,Gorja Ashok et al.
Durga Panikumar Anumolu et al.
The valid method was developed for analyzing empagliflozin in serum/plasma/urine using a molecularly imprinted ghost polymer-solid-phase extraction approach (MISPE) with liquid chromatographic methodology. Methacrylic acid (MAA) was used as...
New Insights into the Quality Control Strategies of Inula racemosa Hook. F. (Pushkarmula) and Saussurea lappa Decne. (Kuth): Medicinal Crops of Alpine Himalaya [0.03%]
高山黄连属药用植物印度聚轮花（Pushkarmul）和大活络草（Kuth）的质量控制策略的新见解
Manish Kumar,Rishabh Bhardwaj,Anil Kumar et al.
Manish Kumar et al.
Adulteration and illegal trade of Saussurea lappa in the name of Inula racemosa is a major issue. Therefore, accurate and easy methods are required to control malpractice and define authenticity. The current study is focused on authenticati...
Quantification of Agnuside in Human Plasma with a Novel High-Performance Liquid Chromatographic Method and Pharmacokinetic Study [0.03%]
一种新型高效液相色谱法定量人血浆中的白术汤并进行药代动力学研究
Derya Egeli,Gizem Tiris,Evrim Kepekci Tekkeli
Derya Egeli
This study presents a combination of High Performance Liquid Chromatography (HPLC) and ultraviolet (UV) detection that provides the quantification of agnuside in human plasma specimens. Reverse-phase chromatographic separation was carried o...
Metal-Organic Frameworks MIL-101(Fe) and MIL-53(Al) as Efficient Adsorbents for Dispersive Micro-Solid-Phase Extraction of Sorafenib in Plasma and Wastewater, Coupled with HPLC-UV Analysis [0.03%]
用于富集血浆和废水中的索拉非尼的高效吸附剂MIL-101（Fe）和MIL-53（Al），并结合HPLC-UV分析
Azra Takhvar,Somaye Akbari,Effat Souri et al.
Azra Takhvar et al.
In the present study, metal-organic frameworks, MIL-101(Fe) and MIL-53(Al), were synthesized under solvothermal conditions and were characterized by Fourier transform infrared spectroscopy, X-ray energy diffraction spectroscopy and scanning...
Quality by Design-Steered Chromatographic Separation and Identification of the Geometric Isomers of Capsiate by Reversed-Phase HPLC and LC-MS [0.03%]
基于质量设计的反相高效液相色谱法和LC-MS法定量卡伟素的几何异构体
Reena Gupta,Bhupinder Kapoor,Monica Gulati et al.
Reena Gupta et al.
An efficient reverse-phase high-performance liquid chromatographic method, based on the design of the experiment approach, was developed for the simultaneous determination of capsiate isomers. Critical method parameters, i.e., flow rate and...
Separation of Three Polar Compounds with Similar Polarities from Swertia mussotii by a Combination of Two Counter-Current Chromatography Modes [0.03%]
应用两种逆流色谱模式组合分离三种极性相似的瑞香狼毒成分
Hongmei Li,Tao Chen,Cheng Shen et al.
Hongmei Li et al.
Separation of polar compounds especially with similar polarities is challenging. In the present study, three polar compounds with similar polarities, including gentiopicroside, sweroside and mangiferin, have been successfully separated from...
Simultaneous Quantification of Biogenic Amines and their Metabolites in Mice Tissue by Combining Ultraviolet and Integrated Pulsed Amperometric Detectors [0.03%]
结合紫外和积分脉冲安培检测器同时定量生物胺及其代谢物在小鼠组织中的含量
Hae-Jee Yoon,Jin Hee Kim,Myung Sook Oh et al.
Hae-Jee Yoon et al.
We developed a reversed-phased high-performance liquid chromatographic method combining ultraviolet detection and integrated pulsed amperometric detection for the simultaneous quantification of dopamine, 5-hydroxyindolacetic acid, homovanil...
Revealing the Active Components and Therapeutic Targets of Sanao Decoction against Chronic Obstructive Pulmonary Disease Using Quantitative Analysis of Multi-Components by Single Marker and Network Pharmacology [0.03%]
基于单标志物的多成分定量分析及网络药理学揭示散寒解热汤治疗慢性阻塞性肺疾病的活性成分及作用靶点
Wanli Ji,Jiahong Wang,Yan Huo et al.
Wanli Ji et al.
As a traditional Chinese medicine, Sanao decoction (SAD) has been used to treat chronic obstructive pulmonary disease (COPD) for multi-years. However, the potential mechanism and targets for its effects of SAD remain unknown. The 94 compone...
Chromatographic Separation and Quantification of Nine Nitrosamine Genotoxic Impurities in a Single Method in Nebivolol Tablet by Using Validated Ultra-Sensitive Liquid Chromatography: Mass Spectrometry Analytical Method [0.03%]
高效液相色谱-质谱法测定 nebivolol 片中九种亚硝胺基因毒性杂质残留量的研究
Mehul Pathak,Dhara D Patel,Dalip Kumar et al.
Mehul Pathak et al.
N-nitrosamine impurities have been detected in a vast variety of drug substances and drug products, showing concern for regulatory aspects. To meet the regulatory requirement for the concerned impurity, a sensitive analytical method capable...
Stability-Indicating Liquid Chromatographic Method Development for the Simultaneous Determination of Amitriptyline Hydrochloride and Propranolol Hydrochloride in Tablet Dosage Form [0.03%]
测定阿米替林盐酸盐和心得安盐酸盐片剂的稳定性指示型液相色谱法的发展
Obi Reddy Chabala,Simon Haque Md,Durai Ananda Kumar Thirumoorthy
Obi Reddy Chabala
The combination of the tricyclic antidepressant amitriptyline hydrochloride (AMH) and the non-selective beta-adrenergic blocker propranolol hydrochloride (PPH) is used for migraine prophylaxis. Higher doses of AMH trigger cardiac arrhythmia...