Greenness Assessment of HPLC-UV Method for Simultaneous Estimation of Four Antihypertensive Drugs [0.03%]
四種抗高血壓藥物 simultaneous estimation 的 HPLC-UV 方法的 Greenness 評估
Kavita Suthar,Sonal Desai
Kavita Suthar
An environmentally friendly HPLC method was developed to estimate angiotensin receptor blocker (telmisartan) and calcium channel blockers (cilnidipine, benidipine and azelnidipine) in a single run. Separation was achieved using a C18 column...
Development and Validation of a Sensitive LC-MS/MS Method for Determination of Deoxythioguanosine in Human DNA and its Application in Thiopurine-Treated Inflammatory Bowel Disease Patients [0.03%]
人DNA中脱氧硫鸟苷的测定法的发展与验证及其在噻嘌呤治疗的炎症性肠病患者中的应用
Jun-Tao Zheng,Jia-He Kong,Ting Yang et al.
Jun-Tao Zheng et al.
Deoxythioguanosine (dTG), incorporated into DNA as DNA-TG, is considered a more relevant thiopurine metabolite than erythrocyte thioguanine nucleotides, as erythrocytes are not the drug target. We established a simple and sensitive liquid c...
Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry Method for Quantification of 3,14,19-Triacetyl Andrographolide in Rat Plasma: Application to Preclinical Pharmacokinetic Studies [0.03%]
大青素三乙酸酯在 rat plasma 中定量的超高压液相色谱-串联质谱法及预临床药代动力学研究中的应用
Chang Ren,Xin Sui,Kunlin Zhang et al.
Chang Ren et al.
3,14,19-triacetyl andrographolide (ADA), a derivative of andrographolide, has emerged as a promising anti-inflammatory compound. In the present study, we established a rapid and sensitive ultra-performance liquid chromatography-tandem mass ...
Development and Validation of a Novel High-Performance Liquid Chromatography Assay with Ultraviolet Detection for Determination of Asciminib in Human Plasma [0.03%]
一种新型人血浆中asciminib测定的高效液相色谱法的建立及验证
Masatomo Miura,Naoto Takahashi
Masatomo Miura
A rapid, simple and highly sensitive stability-indicating high-performance liquid chromatography (HPLC) method was developed and validated for the estimation of asciminib in human plasma. Plasma samples (100 μL) were processed by solid-pha...
A Novel Stability Indicating High Performance Liquid Chromatography Method for Lysergic Acid Diethylamide Quantification: From Microdosing Applications to Broader Analytical Use [0.03%]
一种新型的用于微量给药应用到更广泛分析使用的分光测色法量化二乙基胺莉 Sergic 酸的方法
Mahima Bansal,Estelle Miller,Rachael Sumner et al.
Mahima Bansal et al.
With the rising interest in therapeutic potential of microdosing lysergic acid diethylamide (LSD), accurate quantification and stability analysis are imperative for both scientific research and end-user safety. Currently, high throughput qu...
Analysis of Chemical Constituents in Asarum Heterotropoides Based on High Performance Liquid Chromatography Fingerprint and Ultra Performance Liquid Chromatography Quadrupole Exactive Mass Spectrometry [0.03%]
基于高效液相色谱指纹图和超高效合相色谱四极杆轨道阱质谱的独活化学成分分析
Lian-Yun Du,Zhi Pan,Lu-Sheng Han et al.
Lian-Yun Du et al.
Asarum heterotropoides (AH) is a notable medicinal plant in traditional Chinese medicine (TCM), but distinguishing and assessing its quality from various origins is challenging due to similar morphology and chemical profiles, using traditio...
Validated Environmentally Friendly Chromatographic Determinations of Dacarbazine and its Related Substances [0.03%]
一种新的高效液相色谱法同时测定达卡巴嗪及其有关物质的方法学研究及方法验证
Ibrahim A Naguib,Eglal A Abdelaleem,Eman S Hassan et al.
Ibrahim A Naguib et al.
Sensitive and specific eco-friendly chromatographic approaches were developed to quantitatively determine Dacarbazine along with its United States Pharmacopeia (USP) related impurities simultaneously. Method I was reveresed phase HPLC (RP-H...
Development of a Quantification Method for Procyanidin B1 and B3 in Pine Bark Extracts Using Heart-Cutting HPLC [0.03%]
一种用于测定松树皮提取物中原花青素B1和B3的心切割HPLC定量方法的开发
Ippei Suzuki,Yasuhito Kumai,Jun Takebayashi
Ippei Suzuki
Pine bark extract (PBE) is a material used as a health food. Its functionality is attributed to the antioxidant effect of its contained procyanidins, and quantification of the procyanidin content is important to monitor its quality. However...
Simultaneous Determination of 8, 11, 12, 20-HETEs and 13 s-HODE in Paraquat and Diquat Poisoning Patients Via the UPLC-MS/MS Method [0.03%]
基于UPLC-MS/MS方法同时检测八异构体和十三异前列腺素E2型稳定代谢物在百草枯和双杀灭中毒患者中的意义
Zheng Yu,Xiaofang Ke,Minjie You et al.
Zheng Yu et al.
An Ultra Performance Liquid Chromatography - Mass Spectrometry/Mass Spectrometry (UPL-MS/MS) method for simultaneous determination of 8, 11, 12, 20- hydroxyeicosatetraenoic acids (HETEs) and 13 s-hydroxyoctadecadienoic acid (13 s-HODE) in p...
Harmonized Approach of Design of Experiments with Green and White Analytical Chemistry in Unified Framework for Synchronous Chromatographic Assay of Diverse Combinations of Anti-diabetic Drugs in Pharmaceutical Dosage Forms [0.03%]
基于统一框架的绿色与传统分析化学联合设计实验同步测定药品剂型中多种降糖药组合的方法
Pintu Prajapati,Bageshree Rana,Veerashakar Pulusu et al.
Pintu Prajapati et al.
Antidiabetic drugs, including metformin hydrochloride, are typically used to treat diabetes mellitus. Current methods for evaluating these drug combinations often involve the use of harmful solvents and specific conditions, leading to envir...