Peptides and serotonin control feeding-related events in Rhodnius prolixus [0.03%]
多肽和血清素控制Rhodnius prolixus的摄食相关事件
Ian Orchard
Ian Orchard
Rhodnius prolixus periodically gorges on a blood meal that could compromise salt and water balance. This, however, is prevented by rapid production of urine within minutes of feeding. The Malpighian tubules increase their rate of secretion ...
X Long Zheng,Yasunori Kitamoto,J Evan Sadler
X Long Zheng
Enteropeptidase, a type II transmembrane serine protease, is localized to the brush border of the duodenal and jejunal mucosa. It is synthesized as a zymogen (proenteropeptidase) that requires activation by another protease, either trypsin ...
Different strategies for controlling DNA conformation: compaction and decompaction [0.03%]
调控DNA构象的两种策略：紧缩与舒展
Alfredo Gonzalez-Perez,Rita S Dias
Alfredo Gonzalez-Perez
In the present review we summarize different strategies to induce DNA compaction and decompaction. DNA compaction is achieved using different cationic co-solutes, such as trivalent ions, surfactant, and polycations. In addition, single-chai...
Peng Huang,Lee-Yuan Liu-Chen
Peng Huang
In general, it has been difficult to obtain antibodies which are useful for immunoblotting of endogenous seven-transmembrane receptors (7TMRs) despite the claims made by many companies on commercially available antibodies. In this review, w...
Richard Horuk,Amanda E I Proudfoot
Richard Horuk
The identification of a large cytokine sub-family responsible for the control of the directional migration of leukocytes over 20 years ago brought much excitement to the pharmaceutical industry with the promise of a new family of targets to...
Joan Montaner
Joan Montaner
The use of specific brain biomarkers might aid stroke diagnosis and that approach might permit rapid referral of stroke patients to hospitals with acute treatments, such as t-PA being available. Although thrombolytic therapy in acute stroke...
Carla C Judice,Talita M Marin,Kleber G Franchini
Carla C Judice
Mechanical stress is a major triggering stimulus for the installation of cardiac hypertrophy as well as for the structural and functional deterioration occurring in the hypertrophy decompensation. The sensing of mechanical forces and their ...
Mechanisms of the suppression of free radical overproduction by antioxidants [0.03%]
抗氧化剂抑制自由基过度产生的机制
Vladimir A Kostyuk,Alla I Potapovich
Vladimir A Kostyuk
In accordance with the mechanism of suppression of free radical overproduction in biological systems all antioxidants can be divided into two main groups: chain-breaking antioxidants and preventive antioxidants. Chain-breaking antioxidants,...
Prospects for introducing deferiprone as potent pharmaceutical antioxidant [0.03%]
戴普瑞酮作为高效药物型抗氧化剂的前景研究
George J Kontoghiorghes
George J Kontoghiorghes
Free radical formation is primarily initiated from metal catalytic centers involving iron and copper. Under certain conditions, free radical reactions can lead to free radical cascades and oxidative stress, which can cause biomolecular, cel...
Igor Afanasev
Igor Afanasev
The radical anion of dioxygen superoxide (O2.-) is a physiological free radical formed in various enzymatic processes. On the one hand superoxide is a precursor of reactive oxygen and nitrogen species (hydroxyl radicals, peroxy radicals, hy...