Breaking Tumor Chemoresistance via METTL3 Regulation Enhanced by Sequential Delivery of Dexamethasone [0.03%]
序贯递送糖皮质激素破肿瘤化疗耐药及其METTL3调控机制增强效应
Yan Tang,Changhao Jia,Honglong Ning et al.
Yan Tang et al.
The frequent occurrence of chemoresistance in breast tumors remains a challenge to achieving satisfactory therapeutic efficacy, and a smart drug delivery system with flexible properties is urgently needed to achieve an all-in-one combinatio...
TUBB3/DTX LNPs Dry Powder Inhaler and an Efficient Delivery Device for Targeted Therapy of Lung Cancer [0.03%]
用于肺癌靶向治疗的TUBB3 / DTXLNPs干粉吸入剂及高效给药装置
Mingyuan Li,Xianglong Wang,Mengsi Yin et al.
Mingyuan Li et al.
Lung cancer is the most prevalent and deadly tumor globally, marked by drug resistance and a poor prognosis. Specialized formulations with strong lung targeting are currently lacking. Docetaxel (DTX) and TUBB3-siRNA represent chemotherapy a...
Electronic Structure Modulation Coupled with Vacancy Defect Engineering in FeCoNiCrV High-Entropy Alloy Electrocatalyst for Enhanced Oxygen Evolution Reaction [0.03%]
用于增强氧气析出反应的FeCoNiCrV高熵合金电催化剂的电子结构与空位缺陷工程耦合调控
Deqiang Wang,Yu Zhang,Chuang Zhao et al.
Deqiang Wang et al.
Strategic engineering of composition and defects in high-entropy alloy (HEA) catalysts represents a critical frontier for advancing catalytic technologies, yet this synergistic approach remains underexplored in current materials research. I...
Modification, Degradation, and Mitigation of Perfluorosulfonic Acid Proton Exchange Membranes for Fuel Cells: A Review [0.03%]
燃料电池用全氟磺酸质子交换膜的改性、降解及缓减研究进展综述
Tibebu Shiferaw Kassa,Abdurohman Mengesha Yessuf,Mohamedazeem M Mohideen et al.
Tibebu Shiferaw Kassa et al.
Proton exchange membrane fuel cells (PEMFCs) offer a transformative solution to mitigate climate change by reducing carbon emissions and global carbon footprints. Perfluorosulfonic acid (PFSA) membranes are crucial components of fuel cell s...
Self-Templated Engineering of W3N4 Active Sites on CTF-Derived Tungsten Catalysts: Synergistic Regulation of Mass Transfer, Reaction Pathway, and Oxygen Reduction Activity [0.03%]
CTF衍生的钨催化剂上的W3N4活性位点的自模板工程：协同调节传质，反应路径和氧还原活性
Huan Ye,Yuanzhi Zhu,Qicheng Zhang et al.
Huan Ye et al.
The urgent demand for Pt-free oxygen reduction catalysts drives exploration of tungsten-based alternatives, motivated by its Pt-mimetic valence electron configuration and optimal oxygen binding energy (ΔEO ≈ - 2.05 eV) revealed in oxygen ...
Low-Voltage Tunable Polyvinyl Chloride/Ionic Liquid Gel-Based Lenticular Microlens Arrays for 2D/3D Switchable Displays [0.03%]
基于低电压可调聚氯乙烯/离子液体凝胶的柱面微透镜阵列用于二维/三维可切换显示
Miao Xu,Jing Li,Xueying Chang et al.
Miao Xu et al.
Polyvinyl chloride (PVC) gel is a soft and highly transparent electroactive polymer. Compared to liquid crystal lenses and liquid lenses, PVC gel-based lenses offer advantages such as compactness, polarization independence, and immunity to ...
Integrating DNA-Based Memory in Water-Resistant Electrospun Polymer Fibers for Nondestructive Data Retrieval [0.03%]
用于非破坏性数据检索的耐水聚氨酯纤维电纺丝集成DNA存储
Cecilia Wetzl,Diana Soukarie,Jokin Yeregui Elosua et al.
Cecilia Wetzl et al.
DNA is a digital memory storage medium with advantageous properties, including longevity and high information density. Embedding information-bearing oligonucleotides into materials for long-term storage has gained traction by leveraging mod...
A Simple Method to Prepare a Bioinspired Fog Collection System Combined with Wettability Patterns and Slippery Liquid Infused Porous Surfaces [0.03%]
一种简单的制备结合亲疏水图案与滑移液膜多孔表面仿生集雾系统的方法
Yunjie Guo,Jie Li,Xinchi Li et al.
Yunjie Guo et al.
Freshwater shortage is a growing problem, and inspired by the ultrafast directional water transport structure of the Sarracenia trichomes and the excellent lubrication effect of SLIPS, bionic hierarchical structured surfaces with wettabilit...
Direct Bonding of 6-in. SiC/Si Wafer with Enhanced Thermal Interface [0.03%]
一种改进热界面的六英寸SiC/Si衬底直接键合技术
Szuyu Huang,Fachen Liu,Jiaxin Liu et al.
Szuyu Huang et al.
Silicon-based complementary metal-oxide-semiconductor (CMOS) technology dominates the semiconductor industry but faces fundamental limitations in high-temperature and high-power applications due to its low thermal conductivity and narrow ba...
Self-Delivery Nanotherapeutics for Tumor Low-Temperature Photothermal Immunotherapy through Cascade Heat Shock Protein and Inflammation Inhibition [0.03%]
通过热休克蛋白级联炎症抑制进行肿瘤低温光热免疫治疗的自主递送纳米药物
Xiaoliang Deng,Xianquan Feng,Xiaohui Tang et al.
Xiaoliang Deng et al.
The clinical efficacy of immunotherapy in triple-negative breast cancer (TNBC) faces dual barriers: poor immunogenicity and a suppressive tumor microenvironment. While low-temperature photothermal therapy (LTPTT) has emerged as a potential ...