Angiotensin II and AGTR1 in ESCC Proliferation and Invasion: Insights from the JAK/STAT3 Pathway [0.03%]
血管紧张素II和AGTR1在食管鳞状细胞癌增殖和侵袭中的作用：来自JAK/STAT3通路的启示
Bo Xie,Yuanyuan Gu,Jing Li et al.
Bo Xie et al.
Background: Angiotensin II (Ang II) and its receptor, Angiotensin II receptor type 1 (AGTR1), have been implicated in the proliferation of cancer cells across various tumor types. This study aims to examine the impact of ...
Development of a Radiomic Model to Detect the Retromolar Canal on Panoramic Radiographs [0.03%]
开发用于检测全景片中乙状切迹 canal 的放射模型
Dongjing Zhan,Fei Wang,Donglin Zeng et al.
Dongjing Zhan et al.
Background: The retromolar canal (RMC) is an extension of the mandibular canal located in the distal region of the mandibular third molar. Accurately detecting the RMC using conventional two-dimensional images is challeng...
Effects of Four Main Active Flavonoids of Coreopsis tinctoria Nutt. on Oleic Acid-Induced Lipid Metabolism and Oxidative Stress in HepG2 Cells [0.03%]
紫松果菊四种主要黄酮对油酸诱导的HepG2细胞脂质代谢及氧化应激的影响
Li-Sha Zhao,Rui-Feng Liu,Yu-Tong Kang et al.
Li-Sha Zhao et al.
Background: Traditional Chinese medicines exhibit tremendous beneficial effects on the control of hyperlipidemia and hyperlipidemia-associated disorders. In the present study, we investigated the effects of four Coreopsis...
The Relationship between Hematocrit Levels and Major Adverse Cardiovascular Events in Patients with Acute Myocardial Infarction [0.03%]
血红蛋白水平与急性心肌梗死患者主要心血管事件的关系研究
Yihui Shi,Bin Xu,Jiehong Yang et al.
Yihui Shi et al.
Background: The relationship between hematocrit (HCT) levels and the occurrence of major adverse cardiovascular events (MACEs) in patients with acute myocardial infarction (AMI) remains unexplored. A better understanding ...
Multicenter Study
Discovery medicine. 2025 Feb;37(193):360-371. DOI:10.24976/Discov.Med.202537193.29 2025
Constructing a Multivariate Predictive Model for Postoperative 90-Day Depression Risk in Non-Small Cell Lung Cancer Based on Preoperative Peripheral Blood NLR, LMR, and PLR [0.03%]
基于术前外周血NLR、LMR和PLR构建非小细胞肺癌术后90天抑郁风险的多变量预测模型
Xuefeng Wu,Li Dai,Huajing Guo et al.
Xuefeng Wu et al.
Background: Depression represents a significant clinical concern for individuals diagnosed with non-small cell lung cancer (NSCLC) following surgical resection. This study aimed to investigate the potential of preoperativ...
Mechanisms of Age Differences in the Effectiveness of Phototherapy of Glioblastoma [0.03%]
光疗对胶质母细胞瘤疗效年龄差异的机制
Alexander Shirokov,Nikita Navolokin,Alla Bucharskaya et al.
Alexander Shirokov et al.
Background: Glioblastoma is an incurable and aggressive oncological disease of the brain. Recent studies have shown that transcranial non-invasive photobiomodulation is a promising new alternative method for suppression o...
GNPNAT1 Regulation: A Key Role in Radioimmune Function and NK Cell Resistance in NSCLC [0.03%]
GNPNAT1调节：在非小细胞肺癌中放射免疫功能和NK细胞抵抗的关键作用
Fei Xiang,Yuanfei Dai,Chunfei Yao et al.
Fei Xiang et al.
Background: Glucosamine-6-phosphate N-acetyltransferase 1 (GNPNAT1) is an enzyme involved in the hexosamine biosynthetic pathway, which is critical for glycosylation processes. In the context of non-small cell lung cancer...
ELF1's Role in Colorectal Cancer: Up-Regulating DCLK1 Expression to Propel Malignant Progression and Stemness Features [0.03%]
ELF1在结直肠癌中的作用：通过上调DCLK1的表达促进恶性进展和干性特征
Dongai Zhou,Xiaocai Tian,Hong Yang et al.
Dongai Zhou et al.
Background: Exploring the pathological mechanism of colorectal cancer (CRC) onset and advancement is critical to clinical diagnosis and treatment. In this context, our study brings a novel perspective by investigating the...
Prognostic Significance of a 9-Gene Signature Related to Tertiary Lymphoid Structures in Male Stomach Adenocarcinoma Patients [0.03%]
与男性胃腺癌患者三级淋巴结构相关的9基因标记的预后意义
Zongxiang Yuan,Shihui Huang,Fang Qin et al.
Zongxiang Yuan et al.
Background: The role of tertiary lymphoid structures (TLSs) in stomach adenocarcinoma (STAD) remains unclear despite their known potential effects on tumor progression and prognosis. ...
Urolithin B Promotes Meniscal Regeneration and Prevents the Development of Osteoarthritis in Mice [0.03%]
Urolithin B 促进小鼠半月板再生并防止骨关节炎发展
Wenjun Wang,Husheng Wang,Lin Wang et al.
Wenjun Wang et al.
Background: Osteoarthritis (OA) is one of the most prevalent arthritis types globally, with the knee being particularly susceptible due to its frequent and strenuous use. Urolithin B (UB) exhibits various biological prope...