ACSL6-Mediated Cell Ferroptosis by Inhibiting AMPK Pathway in Periodontitis Stem Cells [0.03%]
在牙周炎干细胞中ACSL6通过抑制AMPK通路介导细胞铁死亡
YaTing Chang,LongHang Chou,ChongMai Zeng et al.
YaTing Chang et al.
Background: Periodontitis is an immunoinflammatory disease. Ferroptosis is a type of inflammation-associated cell death. The article aims to investigate the expression, role, and mechanism of the ferroptosis-related gene ...
Targeting HSF1-TLR9 Axis: Celastrol as a Potential Therapeutic for Liver Injury in Traumatic Hemorrhagic Shock [0.03%]
靶向HSF1-TLR9轴：雷公藤红素作为创伤性出血性休克肝损伤的潜在治疗药物
Jinjiang Zhu,Xiaoyun Sun,Yakun Zhan
Jinjiang Zhu
Background: One of the pharmacological effects of celastrol (Cel) is the amelioration of acute liver injury. In this study, we explored the mechanism of Cel underlying the alleviation of liver injury induced by traumatic ...
Machine Learning Models Based on Stretched-Exponential Diffusion Weighted Imaging to Predict TROP2 Expression in Nude Mouse Breast Cancer Models [0.03%]
基于拉伸指数扩散加权成像的机器学习模型预测裸鼠乳腺癌模型中TROP2表达量
Yi Deng,Chao-Gang Han,Zi-Qin Deng et al.
Yi Deng et al.
Background: Trophoblast cell surface antigen 2 (TROP2) is a promising target for various cancers, including breast cancer. The development of noninvasive techniques for assessing TROP2 expression in tumors holds considera...
Notoginsenoside R1 Promotes Osteogenic Differentiation of Dental Pulp Stem Cells via MAPK Pathway [0.03%]
人参皂苷R1通过MAPK信号通路促进牙髓干细胞的成骨分化
Jijing Yang,Xunben Weng,Cihang Chen et al.
Jijing Yang et al.
Background: Notoginsenoside R1 (NGR1) is a bioactive compound of Panax notoginseng (Burk.) F.H. Chen (PNS), which possesses desirable properties in bone fracture healing and osteogenic differentiation of human periodontal...
Gaurav Kumar Banoriya,Vineet Kumar Singh,Ranjeet Maurya et al.
Gaurav Kumar Banoriya et al.
Bone is an important connective tissue involved in the movement and mechanical support of the body. Its homeostasis refers to the equilibrium between bone formation by osteoblasts and bone resorption by osteoclasts. Hematopoietic progenitor...
Research and Application of Methods for Improving Nail Permeation: A Review [0.03%]
提高甲板渗透方法的研究与应用进展综述
Hongyan Ma,Hongwei Wang
Hongyan Ma
This review aims to explore the current methods and advancements in nail permeation, with a focus on the potential of ultrashort pulse lasers to enhance drug delivery. The treatment of nail diseases, such as onychomycosis, is particularly c...
Biological Therapy and Oral Surgery: Safety Recommendations and Practices [0.03%]
生物治疗与口腔外科手术：安全建议和实践
Atanaska Spasova Dinkova,Petko Georgiev Petrov
Atanaska Spasova Dinkova
The integration of biological therapies, including biologics and biosimilars, into the medical practice has transformed the management of numerous chronic inflammatory, autoimmune, and oncological conditions. However, these treatments can p...
Exploring the Potentials: Therapeutic Uses of Mesenchymal Stem Cells in Treating Corneal Conditions [0.03%]
探索潜能：间充质干细胞在治疗角膜疾病中的治疗应用
Marco Zeppieri,Caterina Gagliano,Fabiana D&#x;Esposito et al.
Marco Zeppieri et al.
Corneal disorders, encompassing injuries, infections, and degenerative diseases, are major contributors to visual impairment globally. Conventional procedures, including corneal transplantation and pharmacological treatments, encounter cons...
Unlocking the Potential of Immunomodulators as Synergistic Immune-Based Therapies in Cancer [0.03%]
免疫调节剂作为癌症中协同免疫疗法的潜力开发
Shivani Tomar,Saleha Siddiqui,Rajiv Pathak et al.
Shivani Tomar et al.
Over the recent years, immunomodulators have opened a new avenue in cancer treatment by virtue of their ability to boost the immune system for neoplastic cell elimination. Improving treatment outcomes by leveraging the interaction of these ...
Afsar U Ahmed
Afsar U Ahmed