Analysis and Investigation of Bioinformatics and Epigenetics Reveal the Underlying Mechanisms by which FLOT2 Modulates the Progression of Diffuse Large B-cell Lymphoma [0.03%]
生物信息学和表观遗传学分析揭示FLOT2调控弥漫性大B细胞淋巴瘤进展的潜在机制
Yujing Zhang,Yao Chen,Qiang Guo et al.
Yujing Zhang et al.
Background: Diffuse large B-cell lymphoma (DLBCL) poses a significant threat to the quality of life for people worldwide. Regrettably, effective treatment strategies for this disease remain elusive in clinical practice du...
Formononetin Restrains Tumorigenesis of Breast Tumor by Restraining STING-NF-κB and Interfering with the Activation of PD-L1 [0.03%]
染料木素通过抑制STING-NF-κB信号轴并干扰PD-L1的激活来限制乳腺肿瘤的发生发展
Hongmei Liu,Zhipeng Wang,Zhigang Liu
Hongmei Liu
Background: Breast cancer (BC), a common tumor in women, has high morbidity and mortality. Formononetin, an active ingredient in red clover and Astragalus membranaceus, has a wide range of pharmacological applications, in...
LncRNA Meg3 Aggravates Renal Fibrosis Caused by Unilateral Ureteral Obstruction in Rats by Activating the Hedgehog Pathway [0.03%]
长链非编码RNA Meg3通过激活Hedgehog信号通路加重单侧输尿管梗阻大鼠肾纤维化
Pei Dong,Sheng Zhang,Da-Jun Hu et al.
Pei Dong et al.
Background: The hedgehog signaling pathway exerts vital functions in regulating epithelial-to-mesenchymal transition (EMT) in renal interstitial fibrosis (RIF). It was reported that lncRNA-maternally expressed gene 3 (lnc...
The Value of Combined Detection of Serum BNP, Cardiac Troponin-I and Dynamic Electrocardiogram in Early Clinical Diagnosis and Prognosis of Patients with Acute Myocardial Infarction [0.03%]
血清BNP、心肌肌钙蛋白-I联合检测和动态心电图在急性心梗患者中的临床应用价值分析
Qinxia Yu,Shuyan Yu
Qinxia Yu
Background: Acute myocardial infarction (AMI) is a prevalent cardiovascular disease resulting from myocardial ischemia and necrosis due to coronary artery occlusion. AMI is characterized by a sudden onset and high mortali...
Application of Acoustic Radiation Force Pulse Imaging Technology in the Evaluation of the Efficacy of Calf Intermuscular Vein Thrombosis [0.03%]
声辐射力脉冲成像技术在评价犊牛股内静脉血栓疗效中的应用
Chengfang Wang,Yijia Zhou,Ruhui Ruan
Chengfang Wang
Background: The continuous advancement in ultrasound technology has given rise to Acoustic Radiation Force Impulse (ARFI) elastography, which boasts non-invasiveness, ease of operation, rapid inspection, and high accuracy...
Phentolamine Protects against Apoptosis and Inflammation in a Neonatal Pneumonia Cell Model Induced by LPS by Regulating the TrkA/Akt Signaling Pathways [0.03%]
酚妥拉明通过调节TrkA/Akt信号通路保护脂多糖诱导的新生儿肺炎细胞模型免受凋亡和炎症的影响
Qian Liu,Shengwei Wu,Zhenlin Chen et al.
Qian Liu et al.
Background: Phentolamine is an α-adrenergic receptor blocker that can be used to treat neonatal pneumonia, but its underlying mechanism is unclear. The purpose of this study is to probe the function of phentolamine on li...
Knockdown of LINC01128 Downregulates FUT8 to Inhibit OxLDL-Induced Vascular Smooth Muscle Cell Apoptosis in Atherosclerosis [0.03%]
LINC01128敲低通过下调FUT8抑制氧化型低密度脂蛋白诱导的动脉粥样硬化血管平滑肌细胞凋亡
Guozhen Ni,Jian Xu
Guozhen Ni
Background: The apoptosis of vascular smooth muscle cells (VSMCs) contributes to the progression of atherosclerosis (AS). Long intergenic non-protein coding RNA 1128 (LINC01128) has been implicated in AS, and this study a...
DNA Methylation-Regulated HOXC8's Role in HER2-Positive Breast Cancer Function and its Contribution to Herceptin Resistance [0.03%]
DNA甲基化调控HOXC8在HER2阳性乳腺癌功能及赫赛汀耐药中的作用
Xiaofeng Xie,Sijia Tang,Zhengyang Yu
Xiaofeng Xie
Background: The epidermal growth factor receptor 2 (HER2) is overexpressed in 30% of breast cancers, and this overexpression is strongly correlated with a poor prognosis. Herceptin is a common treatment for HER2-positive ...
Unlocking the Therapeutic Potential of LncRNA BLACAT1 in Hypopharynx Squamous Cell Carcinoma [0.03%]
探究长链非编码RNA BLACAT1在低咽部鳞状细胞癌治疗中的潜能
Fan-Li Liu,Zhan-Cheng Zhang,Sheng-Li Zhou et al.
Fan-Li Liu et al.
Background: Identifying the key molecular targets in hypopharynx squamous cell carcinoma (HSCC) is crucial for understanding this prevalent and highly fatal type of head and neck tumor. The study aims to enhance comprehen...
Creation of an Atherosclerosis Model Using Palmitic Acid and Oleic Acid in the Vascular Smooth Muscle Cells of Rats [0.03%]
棕榈酸和油酸诱导的大鼠血管平滑肌细胞动脉粥样硬化模型的建立
Fan Zhang,Guangping Li,Xueyin Li et al.
Fan Zhang et al.
Background: Atherosclerosis (AS) is a chronic vascular inflammatory disease resulting from vascular endothelial injury and lipid deposition, closely linked to abnormal lipid metabolism within the body. The critical proces...