Hypoxia-Induced Up-Regulation of ACSS2 Drives the PI3K/AKT/mTOR Pathway Through HMGCS1 to Enhance the Proliferation and Stemness of Pancreatic Cancer Cells [0.03%]
缺氧通过HMGCS1上调ACSS2驱动PI3K/AKT/mTOR途径以增强胰腺癌细胞的增殖和干细胞特性
Zhangcheng Zhao,Gengyu Li,Beibei Zhang et al.
Zhangcheng Zhao et al.
Objective: Pancreatic cancer (PC) is a type of highly malignant tumor associated with poor prognosis, whose progression is driven by hypoxia in the tumor microenvironment. This study aims to explore the effects of hypoxia...
Impact of Unilateral Chemical Injury on Contralateral Unaffected Eyes: A Clinical and Experimental Study [0.03%]
单侧化学伤对侧眼的影响：临床和实验研究
Dan Wu,Jun Xiang,Jing Zhang et al.
Dan Wu et al.
Background: Corneal chemical burns are a common form of ocular injury that can result in severe visual impairment and complications. In recent years, studies have shown that unilateral ocular diseases can induce changes i...
Mechanism of AGT-Mediated Magnesium Ion Uptake in Age-Related Olfactory Dysfunction [0.03%]
AGT介导的镁离子摄取在年龄相关性嗅觉功能障碍中的机制研究
Dong Wang,Jinxiong Yang,Bo Liu et al.
Dong Wang et al.
Background: Ageing is associated with a significant decline in olfactory function, though the underlying mechanisms remain unclear. Angiotensinogen (AGT) participates in multiple cellular processes, including inflammation...
Harnessing the Power of Chlorogenic Acid: Inhibiting IL-2-Mediated Treg Upregulation to Combat Post-Traumatic Osteomyelitis [0.03%]
利用氯ogenic酸抑制IL-2介导的Treg上调对抗创伤后骨髓炎
Yongpei Lin,Zhoutong Wu,Yan Ni et al.
Yongpei Lin et al.
Background: Chlorogenic acid (CGA) exerts immunomodulatory effects by regulating the proportion of regulatory T cells (Tregs), and T-cell dysregulation is a known feature of post-traumatic osteomyelitis (PTO). This study ...
Molecular Characterization and Impact of the Genetic Variants GSTP1, LncRNA H19, TCF7L2 and HNF1A on the Risk of Coronary Artery Disease With and Without T2DM Comorbidity: A Genomic Biomarker Study [0.03%]
GSTP1，基因变异LncRNA H19，TCF7L2和HNF1A的分子特征及其对合并与不合并T2DM的冠心病风险的影响：一种基因生物标志物研究
Pradeep Kumar Dabla,Rashid Mir,Mohammad Fahad Ullah et al.
Pradeep Kumar Dabla et al.
Background: Cardiovascular diseases, including coronary artery disease (CAD), represent one of the leading causes of death worldwide. Individuals with type 2 diabetes mellitus (T2DM) are susceptible to more severe forms o...
Robust and Specific Association Between Seizure at Presentation and Improved Survival in Patients With Primary Brain Tumors [0.03%]
原发性脑肿瘤患者初诊时癫痫发作与生存期改善之间的强相关性研究
Alec G Chen,Truong H Do,Kai Y Chen et al.
Alec G Chen et al.
Background: Whether seizure presentation in patients afflicted with primary brain tumors (PBT) is associated with clinical prognosis remains an open question. We explore this association using the Nationwide Readmission D...
A Review Article: Evaluation of the Frequency of Genetic Mutations in Leukemia [0.03%]
一篇综述文章：评估遗传变异在白血病中的频率
Abdullah Hamadi
Abdullah Hamadi
Leukemia, a group of malignant blood disorders, arises from the uncontrolled proliferation of abnormal white blood cells. Genetic mutations play a critical role in the initiation and progression of leukemia. This review aims to provide an o...
Unveiling Prognostic and Diagnostic Biomarkers in Knee and Hip Osteoarthritis: A Targeted Review [0.03%]
膝骨关节炎和髋骨关节炎的预后及诊断生物标志物的研究进展：靶向综述
Sergiu Andrei Iordache,Adrian Cursaru,Bogdan Serban et al.
Sergiu Andrei Iordache et al.
Osteoarthritis is a multifactorial condition marked by the gradual deterioration of joint cartilage, synovial inflammation, alterations in the subchondral bone and changes in the surrounding soft tissues. Clinical assessments and patient-re...
Carlos Marques Dos Santos,Emanuella Graciela Borges Fonseca,Ana Tereza Amoedo Martinez et al.
Carlos Marques Dos Santos et al.
Investigating Anti-Tumor Effects of Irisin in Cervical Cancer Cells: Cell Viability, Migration, and Tumor-Associated Macrophage Polarization [0.03%]
irisin的抗肿瘤作用及机制研究
Guanyu Cao,Yan Wei,Xiaojie Ma
Guanyu Cao
Background: Cervical cancer is a major concern in women's health. Investigating the biological behavior of cancer cells can help to understand the underlying pathogenesis and offer novel insights into disease management. ...