TNFAIP3 Overexpression Inhibits Diffuse Large B-Cell Lymphoma Progression by Promoting Autophagy through TLR4/MyD88/NF-κB Signaling Pathway [0.03%]
TNFAIP3过表达通过促进TLR4/MyD88/NF-κB信号通路自噬抑制弥漫性大B细胞淋巴瘤进展
Fangying Ning,Huafang Wang,Zuyu Liang et al.
Fangying Ning et al.
Background: Tumor necrosis factor alpha induced protein 3 (TNFAIP3) is reportedly to have significant implications for autophagy regulation in various cancers. The current study aimed to decipher the role and mechanism of...
USP7 Promotes TGF-β1 Signaling by De-Ubiquitinating Smad2/Smad3 in Pulmonary Fibrosis [0.03%]
去泛素化激活Smad2/3促进转化生长因子-β1信号通路在肺纤维化中的作用
Fang Tang,Hongyan Gong,Tiantian Ke et al.
Fang Tang et al.
Background: Idiopathic pulmonary fibrosis (IPF) is a long-term, progressive, and irreversible pulmonary interstitial disease. The activation of Smad family member 2 (Smad2) and Smad3 transcription factors by transforming ...
Data Analysis of Heart Rate Variability and Arrhythmia in Patients with Paroxysmal Atrial Fibrillation [0.03%]
阵发性房颤患者心率变异性及心律失常的数据分析
Huayong Jin,Lijiang Ding,Binglei Li et al.
Huayong Jin et al.
Background: Atrial fibrillation (AF) is the most common type of arrhythmia. Heart rate variability (HRV) may be associated with AF risk. The aim of this study was to test HRV indices and arrhythmias as predictors of parox...
Remimazolam Alleviates Ventilator-Induced Lung Injury by Activating TSPO to Inhibit Macrophage Pyroptosis [0.03%]
雷米唑胺通过激活TSPO抑制巨噬细胞吡啶化以缓解机械通气所致肺损伤
Lei Zhang,Dong Zhao,Huayan Lv et al.
Lei Zhang et al.
Background: Macrophages are activated in ventilator-induced lung injury (VILI), accompanied by macrophage pyroptosis. Remimazolam (Re) plays a role in inhibiting macrophage activation. In this study, we aimed to investiga...
The Effect of Riboflavin on Neurological Rehabilitation after Traumatic Brain Injury in Children [0.03%]
核黄素对儿童创伤性脑损伤后神经康复的影响
Qiao Cai,Bei Zhao,Yuanxiang Ke
Qiao Cai
Background: Traumatic brain injury (TBI), which is the brain impairment and lesion caused by the external force injuring the head and the underlying brain, can cause pediatric death, disability, neurological disorders, an...
Idebenone-Loaded Nanocomposite Microspheres for Nasal Administration-A Perspective in the Treatment of Alzheimer's Disease [0.03%]
用于鼻给药的 Idebenone 载药纳米复合微球在阿尔茨海默病治疗中的应用前景研究
Radka Boyuklieva,Plamen Katsarov,Plamen Zagorchev et al.
Radka Boyuklieva et al.
Background: Alzheimer's disease results in neurodegeneration and is characterized by an accumulation of abnormal neuritic lesions and intracellular aggregates of hyperphosphorylated Tau proteins in the cerebrum. That lead...
Peiyan Wu,Jiaxiang Gao,Guangming Lan et al.
Peiyan Wu et al.
As advances in RNA modification research progress, the significance of 5-methylcytosine (m5C) modification is being increasingly acknowledged. m5C undergoes modification by the methyltransferase NOP2/Sun domain (NSUN) family/DNA methyltrans...
Tailored-Biomaterials Based Potential Strategies for Cardiovascular Disease [0.03%]
基于定制生物材料的心血管疾病潜在治疗策略
Sukhwinder K Bhullar,Haimanti Mondal,John Thomas et al.
Sukhwinder K Bhullar et al.
Cardiovascular disease is a significant health concern worldwide, and varied effective treatment and prevention methods have been developed. Among these, tailored biomaterials-based strategies such as stents, scaffolds, patches, and drug de...
Dietary Diversity and Associated Factors among Children 6-23 Months Old in Ethiopia: Systematic Review and Meta-Analysis [0.03%]
埃塞俄比亚6-23月龄儿童饮食多样性及其影响因素的系统评价和 meta 分析
Sileshi Mulatu,Gebrehiwot Berie Mekonnen,Yeshimebet Tamir Tsehay et al.
Sileshi Mulatu et al.
Background: Feeding diversified food for children is the major indicator of nutritional quality and adequacy that is crucial during the complementary feeding period for infants and young children aged 6-23 months. Ensurin...
Whole-Exome Sequencing Detecting a Recurrent Pathogenic Mutation, HFE p.His63Asp (H63D) in COVID-19 Patients and Its Effect on Mortality [0.03%]
针对COVID-19患者进行全外显子组测序鉴定出一个复发的致病突变HFE p.His63Asp(H63D)及其对死亡率的影响
Rashid Mir,Imadeldin Elfaki,Mohammad A Alanazi et al.
Rashid Mir et al.
Background: In recent years, various coronaviruses have caused severe respiratory illnesses worldwide. For example the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infections of COVID-19 outbreak in 2019 i...