Secretion of GPNMB from Neural Stem Cells Induced by ET-1 Contributes to Angiogenesis after Spinal Cord Injury [0.03%]
脊髓损伤后内源性神经干细胞分泌GPNMB促进血管生成的作用及机制研究
Zhongju Du,Bo Wang,Jie He et al.
Zhongju Du et al.
Background: The feeble plasticity of spinal cord microvascular endothelial cells (SCMECs) after trauma is one of the major causes of spinal cord injury (SCI). Neural stem cells (NSCs) play an important role in nerve repai...
CCT2 Regulates ZEB1-Induced EMT Gene Transcription to Promote the Metastasis and Tumorigenesis of Papillary Thyroid Carcinoma [0.03%]
CCT2通过调节ZEB1诱导的上皮间质转化基因转录促进乳头状甲状腺癌的转移和肿瘤发生
Weiping Liu,Renzhi Lin,Chumeng Zhu et al.
Weiping Liu et al.
Background: Papillary thyroid carcinoma (PTC) is the most common malignant tumor of the thyroid, and its invasiveness and metastatic ability are closely related to patient prognosis. Chaperonin containing TCP1 subunit 2 (...
The Impact of Dibutyl Phthalate on Insulin Signaling in Human Skeletal Muscle Cells [0.03%]
邻苯二甲酸二丁酯对人骨骼肌细胞胰岛素信号的影响
Dan Shan,Yan Chen,Kunyan Zhou
Dan Shan
Background: In China, the environmental concern of Dibutyl Phthalate (DBP) exposure significantly endangers human health by inducing insulin resistance (IR). Skeletal muscle tissue plays a critical role in this process. H...
PCGF2 Acts as an Oncogenic Driver in Colon Cancer through the Upregulation of CENPE [0.03%]
PCGF2通过上调CENPE在结肠癌中充当致癌驱动基因
Qingwei Luo,Xiaoli Chen,Jun Tang et al.
Qingwei Luo et al.
Background: Colon cancer (CC) is a highly prevalent malignancy that contributes significantly to global morbidity and mortality. The polycomb group ring finger 2 (PCGF2) has been identified as a relevant factor influencin...
Hamza Islam,Areeba Siddiqui,Rabia Islam et al.
Hamza Islam et al.
Gastric ulcers induced by non-steroidal anti-inflammatory drug (NSAID) usage have become a common public health problem, and several studies have established chronic NSAID usage to be one of the risk factors for the pathogenesis of peptic u...
Cytogenetics and the Revolution of Optical Genome Mapping in the Diagnosis of Diseases [0.03%]
细胞遗传学和光学基因组测绘在疾病诊断中的革命
Osama M Al-Amer,Yahya Khubrani
Osama M Al-Amer
The study of chromosomal shape, characteristics, and behavior in somatic cell division (mitosis) during growth and development and in germ cell division (meiosis) during reproduction is known as cytogenetics. Many techniques can be used for...
Inflammaging, Epigenetic Damage, Mitochondrial Dysfunctions, and Macrophage Alterations are the Main Missing Pieces in the Complex Mosaic of Stem Cell Physiology [0.03%]
炎症老化、表观遗传损伤、线粒体功能障碍和巨噬细胞改变是干细胞生理复杂马赛克中的主要缺失部分。
Marco Tatullo,Sandro Rengo,Gilberto Sammartino et al.
Marco Tatullo et al.
Aging is frequently associated with a progressive increase in chronic low-grade inflammation, known as "inflammaging". Numerous studies have shown that inflammaging is closely linked to the development of several age-related diseases. Howev...
Valeria Moreno,Ludovic Saba,Sara Tama-Shekan et al.
Valeria Moreno et al.
Systemic light-chain (AL) amyloidosis is a rare and complex clonal plasma cell neoplasm characterized by the production of misfolded and unstable immunoglobulin light-chains leading to multisystem amyloid deposition, which progresses to org...
" Matters Arising" on a Recent Biologic (Ab-IPL-IL-17™) for IL-17-Mediated Diseases [0.03%]
关于最近一种治疗IL-17介导疾病的生物制剂（Ab-IPL-IL-17TM）的几点思考
Anella Saviano,Adel Abo Mansour,Paolo Grieco et al.
Anella Saviano et al.
Regulation of Nrf2/A20/eEF1A2 Axis by Ginsenoside Rb1: A Key Pathway in Alleviating Cerebral Ischemia-Reperfusion Injury [0.03%]
人参皂苷Rb1调节Nrf2/A20/eEF1A2轴：缓解缺血再灌注脑损伤的关键途径
Haijuan He,Yanqing Yang,Xia Zhang et al.
Haijuan He et al.
Background: Cerebral ischemia-reperfusion injury (CIRI) is a prevalent neurological disorder, characterized by the oxidative stress and inflammatory response induced during the ischemia-reperfusion process, leading to sig...