Role of Apolipoprotein E in Alzheimer's Disease Pathogenesis, Prognosis and Treatment [0.03%]
载脂蛋白E在阿尔茨海默病发病机制、预后和治疗中的作用
Allison B Reiss,Mary Housny,Shelly Gulkarov et al.
Allison B Reiss et al.
Alzheimer's disease (AD) is an incurable and progressive neurodegenerative disease with increasing prevalence worldwide. Previous trials of anti-amyloid and anti-tau immunotherapy indicate that additional research needs to be conducted on o...
Daniele Focosi,Fabrizio Maggi
Daniele Focosi
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant of interest BA.2.87.1 has not driven any Coronavirus disease 2019 (COVID-19) pandemic wave. Nevertheless, it has served to test the reaction times of modern virology l...
Antimicrobial Resistance: A Global Public Health Concern that Needs Perspective Combating Strategies and New Talented Antibiotics [0.03%]
抗菌素抗性：一个需要对策和新药的全球公共卫生问题
Abdelazeem Mohamed Algammal,Payam Behzadi
Abdelazeem Mohamed Algammal
No abstract present.
METTL3 Regulates the Translation of Oncogene Myc through m6A Modification and Promotes the Occurrence and Development of Cervical Cancer [0.03%]
METTL3通过m6A修饰调控原癌基因Myc的翻译从而促进宫颈癌的发生发展
Yanyan Ma,Hongyan Shi,Wei Zheng
Yanyan Ma
Background: Cervical cancer (CC) is one of the major types of gynecological cancer, with a high global incidence and mortality rate. Methyltransferase-like 3 (METTL3), a key constituent of methyltransferase, plays a cruci...
A Comparison between Demyelinating and Omicron Variant Infection-Associated Optic Neuritis [0.03%]
脱髓鞘与奥密克戎变异株感染相关视神经炎的比较
Jing Zhang,Lian Wang,Chunli Chen et al.
Jing Zhang et al.
Background: The connection between viral infection and the onset of demyelination has garnered considerable attention. Omicron, the most recent prevalent strain of the severe acute respiratory syndrome coronavirus 2 (SARS...
Comparative Study
Discovery medicine. 2024 Sep;36(188):1891-1901. DOI:10.24976/Discov.Med.202436188.175 2024
Berberine Alleviates Sevoflurane Anesthesia-Induced Cognitive Dysfunction in Neonatal Mice via Regulating CREB1 [0.03%]
巴马汀通过调节CREB1缓解异氟醚吸入致新生小鼠认知障碍的作用及机制研究
Huajuan Wang,Wangsheng Wu,Qunyan Zheng et al.
Huajuan Wang et al.
Background: Sevoflurane has been shown to stimulate neurotoxicity and lead to cognitive impairment. Berberine is known for its role in regulating nervous system diseases, including cognitive dysfunction. This study aimed ...
Association of Microbleeds on Susceptibility-Weighted Imaging with Ferroptosis and Prognosis in Rabbits with Spinal Cord Injury [0.03%]
基于磁敏感加权成像的微出血与脊髓损伤兔模型细胞铁死亡及预后的关系研究
Xing-Zhen Liu,Bo-Cheng Wang,Kang-Ping Shen et al.
Xing-Zhen Liu et al.
Background: Susceptibility-weighted imaging (SWI) is a common imaging technique used to identify cerebral microbleeds. Given that spinal cord injury (SCI) often creates an environment that favors ferroptosis, a type of ce...
KLHDC8A Regulates M1/M2 Macrophage Polarization Through the PD-1/STAT3 Pathway to Promote Papillary Thyroid Cancer Development [0.03%]
KLHDC8A通过PD-1/STAT3信号通路调控M1/M2型巨噬细胞极化促进乳头状甲状腺癌发生发展的机制研究
Yun Peng,Meiling Wen,Jianping Yu et al.
Yun Peng et al.
Background: Papillary thyroid cancer (PTC) is one of the most frequent endocrine malignancies. Kelch domain containing 8A (KLHDC8A) is reported as an epigenetically driven oncogene, but the role of KLHDC8A in PTC is still...
Characterization of Metronidazole, Clarithromycin and Amoxicillin Resistance Genes in Helicobacter pylori Isolated from Gastroenteritis Patients [0.03%]
胃炎患者幽门螺杆菌分离株中甲硝唑、克拉霉素和阿莫西林耐药基因的表征
Somaid Iqbal,Waheed Ullah,Syed Faheem Shah et al.
Somaid Iqbal et al.
Background: Helicobacter pylori (H. pylori)is a Gram-negative, microaerophilic, and spiral shape bacterium that resides inside the human stomach. The human stomach serves as its primary reservoir. Complaints about stomach...
Association between DEFB1 rs11362 and Caries Susceptibility in Permanent Dentition: A Cross Sectional Study [0.03%]
DEFB1基因多态性与恒牙列龋病易感性的相关性研究
Qiulin Liu,Li Liu,Shaoyong Chen et al.
Qiulin Liu et al.
Background: Dental caries is a multifactorial chronic bacterial infectious disease. Variations in the predisposition of the general population to dental cavities suggest that genetic and immunological factors play signifi...