Nuclear Receptor Subfamily 4 Group A Member 3: A Potential Marker of Endometriosis [0.03%]
核受体亚家族4组A成员3：一种潜在的子宫内膜异位症标志物
Yunxiu Huang,Yichuan Guo,Xiaoyan Luo
Yunxiu Huang
Background: Nuclear receptor subfamily 4 group A member 3 (NR4A3) is lowly expressed in ectopic endometrium and can be degraded by ubiquitination in vascular endothelial cells. Murine double minute 2 (MDM2) is predicted t...
Protective Role of TAOK1-CDC20 Axis in Atherosclerosis: Modulation of Endothelial Apoptosis and Senescence [0.03%]
TAOK1-CDC20轴在动脉粥样硬化中的保护作用：调节内皮细胞凋亡和衰老
Yun Qiu,Haiwen Zhou,Haiqiang Ding et al.
Yun Qiu et al.
Background: Atherosclerosis, a chronic inflammatory condition characterized by the accumulation of lipid and fibrous elements in the arterial wall, is a major contributor to cardiovascular disease. This study aimed to inv...
Plasma Extracellular Vesicle-Associated Proteins as Promising Diagnostic Biomarkers of Age-Related Macular Degeneration [0.03%]
血浆外泌体相关蛋白作为诊断年龄相关性黄斑变性的潜在生物标志物
Rouan Chen,Yuxuan Wu,Yiming Fang et al.
Rouan Chen et al.
Background: Age-related macular degeneration (AMD) is a significant factor causing blindness in adults. However, the clinical diagnosis of AMD is relatively challenging, due to the shortcomings of the existing clinical ex...
Mechanism of Interleukin-17A Regulation of Mesenchymal Stroma/Stem Cell Osteogenic Differentiation [0.03%]
白细胞介素17A调节基质/干细胞成骨分化的机制研究
Juan F Santibanez
Juan F Santibanez
The immune and musculoskeletal systems closely interplay in bone repair and regeneration. After bone injury, the body produces high levels of cytokines and signaling molecules to balance bone formation and resorption. Interleukin (IL)-17A, ...
Uncommon but Significant: Onset, Characteristics and Management of Vasculitis and Connective Tissue Diseases Induced by Immunomodulators during Cancer Treatment [0.03%]
不常见但重要：免疫调节剂诱导的癌症治疗期间血管炎和结缔组织病的发生、特点及处理措施
Caterina Gagliano,Roberta Foti,Elisa Visalli et al.
Caterina Gagliano et al.
The introduction of immunomodulators as adjuvant therapies in cancer treatment has represented a significant advancement in oncology, improving therapeutic response and patient survival. Emerging targets and molecules could provide new ther...
Photodynamic Therapy as a Future Method in the Treatment of Parotid Gland Tumor: A Review [0.03%]
光动力疗法作为治疗腮腺肿瘤的未来方法：综述研究
Lidia Bieniasz,Wojciech Domka,David Aebisher et al.
Lidia Bieniasz et al.
Photodynamic therapy (PDT) is emerging as a promising treatment for many diseases. This non-invasive approach uses photosensitizing agents and light to selectively destroy abnormal cells, providing a valuable alternative to traditional trea...
Amélie Foucault,Olivier Hérault
Amélie Foucault
Aldehyde dehydrogenases (ALDHs) constitute a group of enzymes that catalyze the oxidation of aldehydes to carboxylic acids. The human ALDH superfamily, including 19 different isoenzymes (ALDH1A1, ALDH1A2, ALDH1A3, AHDH1B1, ALDH1L1, ALDH1L2,...
Monkeypox Resurgence: A Global Health Challenge Navigating Zoonotic Spillover, Genomic Evolution, and Strategic Response [0.03%]
全球猴痘疫情挑战：人畜共患病溢出、基因组演化及战略应对
Abdelazeem Mohamed Algammal,Muhammad Shafiq
Abdelazeem Mohamed Algammal
Wnt/β-Catenin Pathway-Mediated PD-L1 Overexpression Facilitates the Resistance of Non-Small Cell Lung Cancer Cells to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors [0.03%]
WNT/β-catenin信号介导的PD-L1高表达促进非小细胞肺癌细胞EGFR酪氨酸激酶抑制剂耐药性生成
Zhangdan Huang,Jianjun Wang,Zehai Xia et al.
Zhangdan Huang et al.
Background: Epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) is considered highly effective treatment for advanced non-small cell lung cancer (NSCLC), who often develop drug resistance after 10 months...
Dysregulated Vitamin D, CYP2R1, TCF7L2, and CCR5 Δ32 Gene Variations are Associated with Coronary Artery Disease [0.03%]
维生素D、CYP2R1、TCF7L2和CCR5Δ32基因失调与冠状动脉疾病相关性研究
Jamsheed Javid,Rashid Mir,Imadeldin Elfaki et al.
Jamsheed Javid et al.
Background: Insufficient vitamin D (vit D) levels are associated with various chronic conditions such as cancers, autoimmune diseases, diabetes, and cardiovascular diseases, notably coronary artery disease (CAD). The enzy...