Clinical Implications of Mutations in the PI3K Pathway in HER2+ Breast Cancer: Prognostic or Predictive? [0.03%]
HER2阳性乳腺癌中PI3K通路突变的临床意义：预后因素或预测标志？
Ingrid A Mayer
Ingrid A Mayer
Recent advances in tumor genetics and drug development have led to the generation of a wealth of anti-cancer-targeted therapies. These drugs aim at targeting a particular vulnerability in the tumor generated in most cases as a result of dep...
Weight Loss Intervention for Breast Cancer Survivors: A Systematic Review [0.03%]
乳腺癌幸存者的体重管理干预措施：系统综述
Mary Playdon,Gwendolyn Thomas,Tara Sanft et al.
Mary Playdon et al.
To determine the effectiveness of weight loss intervention for breast cancer survivors. From October 2012 until March 2013, Pubmed was searched for weight loss intervention trials that reported body weight or weight loss as a primary outcom...
Illness Perceptions in Women with Breast Cancer-a Systematic Literature Review [0.03%]
乳腺癌患者的疾病认知-系统文献综述
Ad A Kaptein,Jan W Schoones,Maarten J Fischer et al.
Ad A Kaptein et al.
Women with breast cancer respond to the illness and its medical management in their own personal way. Their coping behavior and self-management are determined by their views (cognitions) and feelings (emotions) about symptoms and illness: t...
Best Practice Guidelines in Assessment, Risk Reduction, Management, and Surveillance for Post-Breast Cancer Lymphedema [0.03%]
乳腺癌后淋巴水肿评估、风险降低、管理和监测的最佳实践指南
Jane M Armer,Jennifer M Hulett,Michael Bernas et al.
Jane M Armer et al.
Breast cancer-related lymphedema (LE) is a progressive, chronic disease that affects millions of cancer survivors and primarily results from surgical lymphatic vessel/node removal and radiation therapy. Patient education and support for imp...
The Evolving Role of Circulating Tumor Cells in the Personalized Management of Breast Cancer: from Enumeration to Molecular Characterization [0.03%]
循环肿瘤细胞在乳腺癌个性化管理中的作用演变：从计数到分子表征
Sasmit Sarangi,Kailash Mosulpuria,Michaela J Higgins et al.
Sasmit Sarangi et al.
Circulating Tumor cells (CTCs) represent tumor cells in the blood stream dislodged from the primary tumor. The presence of CTCs in the bloodstream provides a unique opportunity to sample cancer tissue by means of a relatively less-invasive ...
Vandana G Abramson,Ingrid A Mayer
Vandana G Abramson
Triple-negative breast cancers (TNBCs) are known to be an aggressive group of breast cancers with higher rates of relapse stage for stage compared to ER/PR positive and HER2 positive breast cancers despite optimal loco-regional and systemic...
Therapeutic Considerations in Treating HER2-Positive Metastatic Breast Cancer [0.03%]
HER2阳性转移性乳腺癌的治疗考量
Ciara C O&#x;Sullivan,Karen L Smith
Ciara C O&#x;Sullivan
Despite advances in detection and treatment, metastatic breast cancer (MBC) remains the second highest cause of cancer-related death for women in the United States. Human epidermal growth factor receptor-2 (HER2) is amplified in 25-30% of b...
Understanding Drug Resistance in Breast Cancer with Mathematical Oncology [0.03%]
数学肿瘤学在理解乳腺癌耐药性中的作用
Terisse Brocato,Prashant Dogra,Eugene J Koay et al.
Terisse Brocato et al.
Chemotherapy is mainstay of treatment for the majority of patients with breast cancer, but results in only 26% of patients with distant metastasis living 5 years past treatment in the United States, largely due to drug resistance. The compl...
Importance of Breast Cancer Subtype in the Development of Androgen Receptor Directed Therapy [0.03%]
乳腺癌亚型在开发雄激素受体定向治疗中的重要性
Elgene Lim,Min Ni,Shiliang Cao et al.
Elgene Lim et al.
The androgen receptor (AR) has re-emerged as a potential therapeutic target in breast cancer. This stems from recent progress made in preclinical models, that have recognized important differences in the effect of AR expression on patient o...
Advances in Preventive Therapy for Estrogen-Receptor-Negative Breast Cancer [0.03%]
雌激素受体阴性乳腺癌的预防疗法新进展
Beate C Litzenburger,Powel H Brown
Beate C Litzenburger
Preventing breast cancer is an effective strategy for reducing breast cancer deaths. The purpose of chemoprevention (also termed preventive therapy) is to reduce cancer incidence by use of natural, synthetic, or biological agents. The effic...