Laura M Arthur,Arran K Turnbull,Lucy R Khan et al.
Laura M Arthur et al.
Purpose of review: Pre-operative endocrine therapy can be used to down-stage large or locally advanced breast cancers in ER+ disease. In the last four decades, it has evolved from a treatment perceived as an alternative t...
Diagnostic Methods, Risk Factors, Prevention, and Management of Breast Cancer-Related Lymphedema: Past, Present, and Future Directions [0.03%]
乳腺癌相关淋巴水肿的诊断方法、危险因素、预防和管理：过去、现在和未来方向
Hoda E Sayegh,Maria S Asdourian,Meyha N Swaroop et al.
Hoda E Sayegh et al.
Purpose of review: Breast cancer-related lymphedema (BCRL) is a chronic, adverse, and much feared complication of breast cancer treatment, which affects approximately 20% of patients following breast cancer treatment. BCR...
Mechanisms of Neurotoxic Symptoms as a Result of Breast Cancer and Its Treatment: Considerations on the Contribution of Stress, Inflammation, and Cellular Bioenergetics [0.03%]
乳腺癌及其治疗引起的神经毒性症状机制：考虑压力、炎症和细胞生物能量的贡献
Tamara E Lacourt,Cobi J Heijnen
Tamara E Lacourt
Purpose of review: Breast cancer and its treatment are associated with a range of neurotoxic symptoms, such as fatigue, cognitive impairment, and pain. Although these symptoms generally subside after treatment completion,...
C C O&#x;Sullivan,K J Ruddy
C C O&#x;Sullivan
Breast cancer is the most common non-cutaneous malignancy among women, and there are over 3 million breast cancer survivors living in the United States today. Excellent cure rates with modern therapies are associated with substantial toxici...
CDK4/6 Inhibition in Breast Cancer: Mechanisms of Response and Treatment Failure [0.03%]
乳腺癌中CDK4/6抑制剂的作用机制及其耐药性机制研究进展
Ana C Garrido-Castro,Shom Goel
Ana C Garrido-Castro
Purpose of review: To describe the role of D-type cyclins and CDKs 4 and 6 in breast cancer, and to discuss potential biomarkers for sensitivity or resistance to CDK4/6 inhibitors. ...
The Abscopal Effect of Radiation Therapy: What Is It and How Can We Use It in Breast Cancer? [0.03%]
放射治疗的 абскопальный效应：它是什麼以及如何用於乳腺癌？
Zishuo I Hu,Heather L McArthur,Alice Y Ho
Zishuo I Hu
The abscopal effect refers to the ability of localized radiation to trigger systemic antitumor effects. Over the past 50 years, reports on the abscopal effect arising from conventional radiation have been relatively rare. However, with the ...
Reducing the Risk of Breast Cancer Recurrence: an Evaluation of the Effects and Mechanisms of Diet and Exercise [0.03%]
饮食和运动降低乳腺癌复发风险的效果及其机制评价研究
Christina M Dieli-Conwright,Kyuwan Lee,Jacqueline L Kiwata
Christina M Dieli-Conwright
With recent medical advances in diagnosis and treatment, the increasing numbers of long-term survivors of breast cancer is considerable and has resulted in the expansion of scientific research to include examination of lifestyle modificatio...
Susan Hum,Melinda Wu,Sandhya Pruthi et al.
Susan Hum et al.
The uptake of selective estrogen receptor modulators (SERMs) and aromatase inhibitors (AIs) for the primary prevention of breast cancer is low, despite their proven efficacy in several randomized clinical trials. This review summarizes the ...
R Douglas Macmillan,Stephen J McCulley
R Douglas Macmillan
Oncoplastic surgery is integral to all breast cancer surgeries. The use of an aesthetic approach to breast conservation or mastectomy greatly enhances the range of options that can be offered to women with breast cancer and facilitates bett...
Clinical Implications of Mutations in the PI3K Pathway in HER2+ Breast Cancer: Prognostic or Predictive? [0.03%]
HER2阳性乳腺癌中PI3K通路突变的临床意义：预后因素或预测标志？
Ingrid A Mayer
Ingrid A Mayer
Recent advances in tumor genetics and drug development have led to the generation of a wealth of anti-cancer-targeted therapies. These drugs aim at targeting a particular vulnerability in the tumor generated in most cases as a result of dep...