Samuel Wieser,Jonathon Pines
Samuel Wieser
In this article, we will discuss the biochemistry of mitosis in eukaryotic cells. We will focus on conserved principles that, importantly, are adapted to the biology of the organism. It is vital to bear in mind that the structural requireme...
Won-Suk Chung,Nicola J Allen,Cagla Eroglu
Won-Suk Chung
Astrocytes, through their close associations with synapses, can monitor and alter synaptic function, thus actively controlling synaptic transmission in the adult brain. Besides their important role at adult synapses, in the last three decad...
May-Britt Moser,David C Rowland,Edvard I Moser
May-Britt Moser
The hippocampal system is critical for storage and retrieval of declarative memories, including memories for locations and events that take place at those locations. Spatial memories place high demands on capacity. Memories must be distinct...
May-Britt Moser,David C Rowland,Edvard I Moser
May-Britt Moser
The hippocampal system is critical for storage and retrieval of declarative memories, including memories for locations and events that take place at those locations. Spatial memories place high demands on capacity. Memories must be distinct...
Tom Sexton,Eitan Yaffe
Tom Sexton
Despite a growing understanding of how epigenetic marks such as histone modifications locally modify the activity of the chromatin with which they are associated, we know little about how marked regions on different parts of the genome are ...
Andrew B Reams,John R Roth
Andrew B Reams
Changes in gene copy number are among the most frequent mutational events in all genomes and were among the mutations for which a physical basis was first known. Yet mechanisms of gene duplication remain uncertain because formation rates ar...
DNA-pairing and annealing processes in homologous recombination and homology-directed repair [0.03%]
同源重组和同源 directed 修复过程中的 DNA 配对及退火过程
Scott W Morrical
Scott W Morrical
The formation of heteroduplex DNA is a central step in the exchange of DNA sequences via homologous recombination, and in the accurate repair of broken chromosomes via homology-directed repair pathways. In cells, heteroduplex DNA largely ar...
Jingyan Fu,Iain M Hagan,David M Glover
Jingyan Fu
The centrosome was discovered in the late 19th century when mitosis was first described. Long recognized as a key organelle of the spindle pole, its core component, the centriole, was realized more than 50 or so years later also to comprise...
Jingyan Fu,Iain M Hagan,David M Glover
Jingyan Fu
The centrosome was discovered in the late 19th century when mitosis was first described. Long recognized as a key organelle of the spindle pole, its core component, the centriole, was realized more than 50 or so years later also to comprise...
Ivana Y Kuo,Barbara E Ehrlich
Ivana Y Kuo
Signaling pathways regulate contraction of striated (skeletal and cardiac) and smooth muscle. Although these are similar, there are striking differences in the pathways that can be attributed to the distinct functional roles of the differen...