Maria Spies,Richard Fishel
Maria Spies
Homologous recombination (HR) and mismatch repair (MMR) are inextricably linked. HR pairs homologous chromosomes before meiosis I and is ultimately responsible for generating genetic diversity during sexual reproduction. HR is initiated in ...
Larry R Squire,Adam J O Dede
Larry R Squire
The idea that memory is not a single mental faculty has a long and interesting history but became a topic of experimental and biologic inquiry only in the mid-20th century. It is now clear that there are different kinds of memory, which are...
Neil Brockdorff,Bryan M Turner
Neil Brockdorff
Many organisms show major chromosomal differences between sexes. In mammals, females have two copies of a large, gene-rich chromosome, the X, whereas males have one X and a small, gene-poor Y. The imbalance in expression of several hundred ...
Michael Lisby,Rodney Rothstein
Michael Lisby
Homologous recombination provides high-fidelity DNA repair throughout all domains of life. Live cell fluorescence microscopy offers the opportunity to image individual recombination events in real time providing insight into the in vivo bio...
Victoria L Bautch,Kathleen M Caron
Victoria L Bautch
Blood and lymphatic vessels deliver oxygen and nutrients, remove waste and CO2, and regulate interstitial pressure in tissues and organs. These vessels begin life early in embryogenesis using transcription factors and signaling pathways tha...
Tatsuya Hirano
Tatsuya Hirano
The primary goal of mitosis is to partition duplicated chromosomes into daughter cells. Eukaryotic chromosomes are equipped with two distinct classes of intrinsic machineries, cohesin and condensins, that ensure their faithful segregation d...
Marc R Freeman
Marc R Freeman
Molecular genetic approaches in small model organisms like Drosophila have helped to elucidate fundamental principles of neuronal cell biology. Much less is understood about glial cells, although interest in using invertebrate preparations ...
John H Byrne,Robert D Hawkins
John H Byrne
The simplicity and tractability of the neural circuits mediating behaviors in invertebrates have facilitated the cellular/molecular dissection of neural mechanisms underlying learning. The review has a particular focus on the general princi...
Cytokinesis in animal cells [0.03%]
动物细胞的胞质分裂
Pier Paolo D&#x;Avino,Maria Grazia Giansanti,Mark Petronczki
Pier Paolo D&#x;Avino
Cell division ends with the physical separation of the two daughter cells, a process known as cytokinesis. This final event ensures that nuclear and cytoplasmic contents are accurately partitioned between the two nascent cells. Cytokinesis ...
Bruno Weber,L Felipe Barros
Bruno Weber
Brain metabolism is characterized by fuel monodependence, high-energy expenditure, autonomy from the rest of body, local recycling, and marked division of labor between cell types. Although neurons spend most of the brain's energy on signal...