Hsp72-Based Effect and Mechanism of Microwave Radiation-Induced Cardiac Injury in Rats [0.03%]
微波辐射致大鼠心脏损伤的热休克蛋白72介导效应及机制研究
Dayan Li,Xinping Xu,Yabing Gao et al.
Dayan Li et al.
The purpose of this study was to determine the role of heat shock protein 72 (Hsp72) changes in cardiac injury caused by microwave radiation, aimed at providing novel insights into the mechanism of this damage. A digital thermometer was use...
Marine-Derived Piericidin Diglycoside S18 Alleviates Inflammatory Responses in the Aortic Valve via Interaction with Interleukin 37 [0.03%]
海洋来源的穿孑L酸二糖苷S18通过与白细胞介素37相互作用缓解主动脉瓣炎症反应
Shunyi Li,Jianglian She,Jingxin Zeng et al.
Shunyi Li et al.
Calcific aortic valve disease (CAVD) is a valvular disease frequently in the elderly individuals that can lead to the valve dysfunction. Osteoblastic differentiation of human aortic valve interstitial cells (HAVICs) induced by inflammation ...
HDAC8 Promotes Liver Metastasis of Colorectal Cancer via Inhibition of IRF1 and Upregulation of SUCNR1 [0.03%]
组蛋白去乙酰化酶8通过抑制IRF1和上调SUCNR1促进结直肠癌肝转移
Jierong Chen,Lixue Cao,Jianhong Ma et al.
Jierong Chen et al.
Histone deacetylases (HDACs) are well-characterized for their involvement in tumor progression. Herein, the current study set out to unravel the association of HDAC8 with colorectal cancer (CRC). Bioinformatics analyses were carried out to ...
Qinbaohong Zhike Oral Liquid Attenuates LPS-Induced Acute Lung Injury in Immature Rats by Inhibiting OLFM4 [0.03%]
秦宝虹止咳口服液通过抑制OLFM4减轻内毒素诱导的幼年大鼠急性肺损伤
Fangbo Zhang,Yu Li,Yujie Xi et al.
Fangbo Zhang et al.
Acute respiratory infections (ARIs) are a common public safety threat with high morbidity and mortality in pediatric patients worldwide. Qinbaohong Zhike oral liquid (QBH), a marketed traditional Chinese medicine product, has been widely us...
Pharmacotherapies for Central Post-Stroke Pain: A Systematic Review and Network Meta-Analysis [0.03%]
卒中后中枢性疼痛的药物治疗：系统评价和网络 meta 分析
Zheng Bo,Yang Jian,Li Yan et al.
Zheng Bo et al.
Background: Central post-stroke pain (CPSP) is a common condition. Several pharmacotherapies have been applied in practice. However, the comparative effectiveness among these pharmacotherapies is unknown. ...
Integrating Transcriptomics and Free Fatty Acid Profiling Analysis Reveal Cu Induces Shortened Lifespan and Increased Fat Accumulation and Oxidative Damage in C. elegans [0.03%]
整合转录组学和游离脂肪酸谱分析揭示Cu诱导C.elegans寿命缩短、脂肪积累增加及氧化损伤产生
Ying Zhang,Qian Zhou,Lu Lu et al.
Ying Zhang et al.
Nowadays, human beings are exposed to Cu in varieties of environmental mediums, resulting in health risks needing urgent attention. Our research found that Cu shortened lifespan and induced aging-related phenotypes of Caenorhabditis elegans...
Therapeutic Effect of Melatonin in Premature Ovarian Insufficiency: Hippo Pathway Is Involved [0.03%]
褪黑素治疗早发性卵巢功能不全的疗效：Hippo信号通路参与其中
Ming Kang Qi,Tie Cheng Sun,Li Ya Yang et al.
Ming Kang Qi et al.
Objective: Premature ovarian insufficiency (POI) is a female reproductive disorder of unknown etiology with no definite pathogenesis. Melatonin (MT) is an endogenous hormone synthesized mainly by pineal cells and has stro...
Ligustilide Improves Cognitive Impairment via Regulating the SIRT1/IRE1 α/XBP1s/CHOP Pathway in Vascular Dementia Rats [0.03%]
通过调节山羊脑SIRT1/IRE1 α/XBP1s/CHOP信号通路改善血管性痴呆大鼠认知障碍作用及机制研究
Dong Peng,Yi-Xue Wang,Tian-Hua Huang et al.
Dong Peng et al.
Vascular dementia (VaD), the second cause of dementia, is caused by chronic cerebral hypoperfusion, producing progressive damage to cerebral cortex, hippocampus, and white matter. Ligustilide (LIG), one of the main active ingredients of Ang...
Herbal Ingredients in the Prevention of Breast Cancer: Comprehensive Review of Potential Molecular Targets and Role of Natural Products [0.03%]
中药在乳腺癌预防中的作用：潜在分子靶点及天然产物的作用综述
Esra Küpeli Akkol,Hilal Bardakci,Timur Hakan Barak et al.
Esra Küpeli Akkol et al.
Among various cancers, breast cancer is the most prevalent type in women throughout the world. Breast cancer treatment is challenging due to complex nature of the etiology of disease. Cell division cycle alterations are often encountered in...
Polysaccharides from Garlic Protect against Liver Injury in DSS-Induced Inflammatory Bowel Disease of Mice via Suppressing Pyroptosis and Oxidative Damage [0.03%]
大蒜多糖通过抑制焦亡和氧化损伤保护炎性肠病致小鼠肝损伤
Xinyi Zhan,Weijie Peng,Zhuqiang Wang et al.
Xinyi Zhan et al.
Inflammatory bowel disease (IBD), a widespread intestinal disease threatening human health, is commonly accompanied by secondary liver injury (SLI). Pyroptosis and oxidative stress act as an important role underlying the pathophysiology of ...