Overexpression of hsa_circ_0061817 Can Inhibit the Proliferation and Invasion of Lung Cancer Cells Based on Active Compounds [0.03%]
hsa_circ_0061817过表达通过激活化合物抑制肺癌细胞增殖和侵袭作用
Longping Ye,Youqing Zhong,Lihua Hu et al.
Longping Ye et al.
Objective: This study was aimed at investigating the expression level of hsa_circ_0061817 in lung adenocarcinoma cells and its effect on cell proliferation and invasion and the possible mechanism of hsa_circ_0061817 in lu...
Ferroptosis Induction Improves the Sensitivity of Docetaxel in Prostate Cancer [0.03%]
诱导铁死亡改善前列腺癌紫杉醇敏感性
Xiumei Chen,Yang Yu,Sudong Liang et al.
Xiumei Chen et al.
Docetaxel resistance seriously affects its clinical application in prostate cancer (PCa). Ferroptosis is a type of iron-dependent cell death driven by lipid peroxidation. It has been recently found that ferroptosis influences various biolog...
Lycopene Ameliorates Hypoxic Pulmonary Hypertension via Suppression of Oxidative Stress [0.03%]
番茄红素通过抑制氧化应激缓解缺氧性肺高血压
Dingyou Wang,Yuke Ji,Rui Wang et al.
Dingyou Wang et al.
Hypoxic pulmonary hypertension (HPH) is a progressive cardiopulmonary system disease characterized by pulmonary vascular remodeling. Its occurrence and progression are closely related to oxidative stress. Lycopene, extracted from red vegeta...
Quantitative Crotonylome Analysis Reveals the Mechanism of Shenkang Injection on Diabetic Nephropathy [0.03%]
量化分析金荞麦茋醌酰胺类成分肾康注射液治疗糖尿病肾脏疾病的定量克龙诺组学分析揭示了肾康注射液治疗糖尿病肾病的机制
Min Wang,Bin Zhang,Chenyang Zhang et al.
Min Wang et al.
Shenkang injection (SKI) has been widely used in the clinical treatment of chronic kidney diseases in China because of its efficacy and safety. However, the underlying mechanism of SKI in diabetic nephropathy (DN) remains unclear. The prese...
Coprophagy Prevention Affects the Reproductive Performance in New Zealand White Rabbits Is Mediated through Nox4-ROS-NF κ B Pathway [0.03%]
粪食预防通过Nox4-ROS-NF κ B途径影响新西兰大白兔的生殖性能
Zhichao Li,RuiTing Li,Jing Li et al.
Zhichao Li et al.
Coprophagy is of great significance to the growth, development, and reproductive performance of rabbits. This study is aimed at exploring the effect of coprophagy on the reproductive performance of New Zealand white rabbits by coprophagy pr...
RBM10 Is a Biomarker Associated with Pan-Cancer Prognosis and Immune Infiltration: System Analysis Combined with In Vitro and Vivo Experiments [0.03%]
基于体内外实验的泛癌分析：揭示RBM10与预后和免疫浸润的相关性
Yingyue Cao,Luyi Pang,Shi Jin
Yingyue Cao
RNA binding motif protein 10 (RBM10) is a splicing factor that has been reported to be involved in the occurrence and progression of multiple malignancies. However, the RBM10 involvement in pan-cancer immunotherapy is not clear. In here, we...
Triptonide Inhibits the Cervical Cancer Cell Growth via Downregulating the RTKs and Inactivating the Akt-mTOR Pathway [0.03%]
三尖杉碱通过下调受体酪氨酸激酶抑制宫颈癌细胞的生长
Li-Na Zhou,Shi-Qing Peng,Xue-Lian Chen et al.
Li-Na Zhou et al.
The high incidence and mortality of cervical cancer (CC) require an urgent need for exploring novel valuable therapeutics. Triptonide (TN) is a small molecule monomer extracted from the Chinese herb Tripterygium wilfordii Hook. Our results ...
Protective Effect of Brassica rapa Polysaccharide against Acute High-Altitude Hypoxia-Induced Brain Injury and Its Metabolomics [0.03%]
芸苔多糖对急性高缺氧致脑损伤的保护作用及代谢组学研究
Xuemei Zou,Hailing Yang,Qiuyue Li et al.
Xuemei Zou et al.
Brassica rapa L., a traditional Tibetan medicine, has been wildly used for treating plateau disease. Polysaccharide is an important chemical component in B. rapa. The present study aimed to evaluate the effect of B. rapa polysaccharide (BRP...
Relationship among Dietary Intake of Vitamin E, Lipid Peroxidation Markers, and C-Reactive Protein in Flu-Like Patients Diagnosed with COVID-19 [0.03%]
维生素E摄入量、脂质过氧化标志物和C反应蛋白在新冠肺炎导致的类流感症状患者中的关系研究
Maísa Guimarães Silva Primo,Liriane Andressa Alves da Silva,Vanessa Brito Lira de Carvalho et al.
Maísa Guimarães Silva Primo et al.
Objective: This research aimed to assess the intake of vitamin E and its relationship with lipid peroxidation markers and C-reactive protein levels in patients with flu symptoms and COVID-19 diagnosis. ...
The Effects of Silymarin on Calcium Chloride-Induced Arrhythmia in Male Rat [0.03%]
水飞蓟素对大鼠钙氯化钙致心律失常的影响
Fereshteh Toghroli,Mohammad Foad Noorbakhsh,Javad Sajedianfard
Fereshteh Toghroli
Antioxidants play an important role in protecting cardiac arrhythmias. Silymarin, strong antioxidant, is effective in reducing the complications caused by arrhythmias. This study was conducted to determine the effect of silymarin on the pre...