Paola Matarrese,Rossella Puglisi,Gianfranco Mattia et al.
Paola Matarrese et al.
Vitiligo is a skin disease that affects all ethnicities and genders and is characterized by the loss of pigment essentially due to the selective loss of melanocytes. Although it is generally considered a systemic disease associated with pol...
Epithelial-Mesenchymal Transition Induced by a Metal Mixture in Liver Cells With Antioxidant Barrier Decreased [0.03%]
抗氧化屏障降低时金属混合物诱导的肝细胞上皮间质转化
M Valverde,P Rosales-Cruz,E Torrejon-Gonzalez et al.
M Valverde et al.
Occupational exposure to arsenic (As), cadmium (Cd), and lead (Pb) affects many sectors, necessitating research to understand their transformation mechanisms. In this study, we characterized the process of epithelial-mesenchymal transition ...
Justice Afrifa,Eric Gyamerah Ofori,Yeboah Kwaku Opoku et al.
Justice Afrifa et al.
Background: Schistosomiasis is considered one of the most devastating parasitic diseases globally, coming second only to malaria in terms of morbidity. The disease-causing parasite can inhabit the body for over a decade, leading to imbalanc...
Coadministration of Monophosphoryl Lipid and Curcumin Modulates Neuroprotective Effects in LPS Stimulated Rat Primary Microglial Cells [0.03%]
单磷酸脂质与姜黄素联合给药可调节LPS刺激的原代大鼠小胶质细胞中神经保护作用
Maryam Hooshmand,Ahmad Asoodeh
Maryam Hooshmand
Lipopolysaccharide (LPS)-induced activation of microglia triggers the release of neuroinflammatory molecules, contributing to the progression of neurodegenerative diseases. Targeting these neuroinflammatory molecules could serve as a potent...
Neuroprotective Effects of Trimetazidine against Cisplatin-Induced Peripheral Neuropathy: Involvement of AMPK-Mediated PI3K/mTOR, Nrf2, and NF- κ B Signaling Axes [0.03%]
曲美他嗪对顺铂诱导的外周神经病变的神经保护作用：AMPK介导的PI3K/mTOR、Nrf2和NF- κ B信号轴的参与
Marawan A Elbaset,Sherif M Afifi,Tuba Esatbeyoglu et al.
Marawan A Elbaset et al.
Cisplatin-induced peripheral neuropathy (CIPN) is a common and debilitating side effect of cisplatin chemotherapy used in cancer treatment. This study explored the neuroprotective effects of Trimetazidine (TRI) against CIPN by preserving ne...
Beniam Worku,Nafyad Tolossa
Beniam Worku
Moringa oleifera, which is known as a drumstick tree in different areas of the world, is well-known for many health benefits, which are attributed to the abundance of flavonoids, phenolic chemicals, and thiocyanates it contains. This review...
EXPRESSION OF CONCERN: Opuntiol Prevents Photoaging of Mouse Skin via Blocking Inflammatory Responses and Collagen Degradation [0.03%]
表达关切：仙人掌(Opuntia)通过阻断炎症反应和胶原蛋白降解来预防小鼠皮肤光老化
Oxidative Medicine And Cellular Longevity
Oxidative Medicine And Cellular Longevity
The Modulatory Effect of an Ethanolic Extract of Anredera cordifolia (Ten.) on the Proliferation and Migration of Hyperglycemic Fibroblasts in an In Vitro Diabetic Wound Model [0.03%]
安格勒德蔓地瓜的乙醇提取物调节体外糖尿病伤口模型中高糖诱导的成纤维细胞增殖和迁移的作用研究
Elisa Vanessa Heisler,Bárbara Osmarim Turra,Nathália Cardoso de Afonso Bonotto et al.
Elisa Vanessa Heisler et al.
Diabetes mellitus is associated with chronic wound-healing problems that significantly impact patients' quality of life and substantially increase expenditure on healthcare. Therefore, the identification of compounds that can aid healing is...
The Combined Effect of Green Tea, Saffron, Resveratrol, and Citicoline against Neurodegeneration Induced by Oxidative Stress in an In Vitro Model of Cognitive Decline [0.03%]
绿茶、藏红花、白藜芦醇和胞磷胆碱联合对抗认知衰退的氧化应激诱导神经退行性变的体内模型中的效果研究
Simone Mulè,Sara Ferrari,Giorgia Rosso et al.
Simone Mulè et al.
During ageing, the brain is vulnerable to a growing imbalance of the antioxidant defence system, resulting in increased oxidative stress. This condition may be mainly responsible for cognitive decline, resulting in synaptic transmission dis...
Emodin Attenuates the ECM Degradation and Oxidative Stress of Chondrocytes through the Nrf2/NQO1/HO-1 Pathway to Ameliorate Rat Osteoarthritis [0.03%]
大黄素通过Nrf2/NQO1/HO-1通路缓解软骨细胞外基质降解和氧化应激以改善膝关节炎
Tianwen Ma,Yuanqiang Ma,Yue Yu et al.
Tianwen Ma et al.
Osteoarthritis (OA) substantially reduces the quality of life of the elderly. OA therapy remains a challenge since no treatment options for its causes are so far available. Over recent years, researchers have speculated that emodin may repr...