Jos J M Westenberg
Jos J M Westenberg
Prevalence of heart failure with preserved left ventricular ejection fraction amounts to 50% of all cases with heart failure. Diagnosis assessment requires evidence of left ventricular diastolic dysfunction. Currently, echocardiography is t...
Damian J Tyler
Damian J Tyler
Many applications of MRI are limited by an inherently low sensitivity. Previous attempts to overcome this insensitivity have focused on the use of MRI systems with stronger magnetic fields. However, the gains that can be achieved in this wa...
Andrew G Howarth,Matthias G Friedrich
Andrew G Howarth
Imaging of cardiac function and anatomy has advanced at an exponential rate over the past two decades. Our ability to quantitatively assess the degree of myocardial ischemia and accurately define the vascular anatomy using noninvasive techn...
Noninvasive Positron Emission Tomography Imaging of Coronary Arterial Inflammation [0.03%]
非侵入性正电子发射断层扫描成像评估冠状动脉炎症
Amr Abdelbaky,Ahmed Tawakol
Amr Abdelbaky
The importance of inflammation to atherothrombosis has led to the pursuit of noninvasive imaging methods to measure inflammation within the arterial wall. There is substantial evidence supporting the use of (18)F-fluorodeoxyglucose positron...
Yijen L Wu,Qing Ye,Chien Ho
Yijen L Wu
Heart transplantation is now an established treatment for patients suffering from end-stage heart diseases. With the advances in immunosuppressive treatment, the survival rate for transplant patients has improved greatly. However, allograft...
F-FDG PET Imaging of Atherosclerosis-A New Approach to Detect Inflamed, High-Risk Coronary Plaques? [0.03%]
FDG PET在动脉粥样硬化中的应用——一种检测易损斑块炎性的新方法吗？
William J Hucker,Farouc A Jaffer
William J Hucker
Imaging of Oxidation-Specific Epitopes in Atherosclerosis and Macrophage-Rich Vulnerable Plaques [0.03%]
动脉粥样硬化和富含巨噬细胞的易损斑块中的氧化特异性表位影像学研究
Karen C Briley-Saebo,Young Seok Cho,Sotirios Tsimikas
Karen C Briley-Saebo
Oxidative stress, and in particular oxidation of lipoproteins, is a hallmark of atherosclerosis. Upon entry of lipoproteins into the vessel wall, a cascade of pro-atherogenic pathways is initiated whereby the reaction of reactive oxygen spe...
Katie L Ciesienski,Peter Caravan
Katie L Ciesienski
This review focuses on recent approaches in using targeted MRI probes for noninvasive molecular imaging of thrombosis. Probe design strategies are discussed: choice of molecular target; nanoparticle versus small-molecule probe; and gadolini...
Yasumi Uchida,Yasuto Uchida
Yasumi Uchida
Drug-eluting stents (DES) reduce coronary restenosis significantly; however, late stent thrombosis (LST) occurs, which requires long-term antiplatelet therapy. Angioscopic grading of neointimal coverage of coronary stent struts was establis...
Shuning Huang,David E Sosnovik
Shuning Huang
The past year has witnessed ongoing progress in the field of molecular MRI of the myocardium. In addition, several novel fluorescent agents have been introduced and used to image remodeling in the injured myocardium. New techniques to image...