The Shifting and Evolving Neoadjuvant Treatments and Surgical Platforms on Oncological Outcomes and Sphincter Preservation in Distal Rectal Cancer: A 23-Year Retrospective Experience [0.03%]
新辅助治疗和手术方式对低位直肠癌的肿瘤学结局及保肛率的影响：一项23年的回顾性研究经验
Niyaz Shadmanov,Vusal Aliyev,Barıs Bakır et al.
Niyaz Shadmanov et al.
Purpose: This study aims to evaluate how advancements in surgical technology and evolving neoadjuvant treatment (NAT) protocols have influenced clinical, pathological, and long-term oncological outcomes in patients with l...
Does Omitting Additional Surgery After Local Resection Affect Oncological Outcomes in Patients with High-Risk pT1 Colorectal Cancer? [0.03%]
初治高危pT1期结直肠癌患者遗漏额外手术是否影响肿瘤结局？
Begoña Oronoz,Javier Suárez,Susana Oquiñena et al.
Begoña Oronoz et al.
Introduction: Colorectal cancer (CRC) is a leading cause of cancer-related mortality in Spain, with pT1 adenocarcinomas often managed via endoscopic polypectomy (EP). Determining the necessity of additional surgery post-E...
Neutrophil-to-Lymphocyte Ratio (NLR) as a Predictive Biomarker in Advanced Hepatocellular Carcinoma Treated with First-Line Immunotherapy [0.03%]
中性粒细胞与淋巴细胞比率（NLR）作为一线免疫治疗的晚期肝细胞癌患者的预测标志物
Tiago Felismino,Luanna Martins,Matheus Barroso et al.
Tiago Felismino et al.
Purpose: Hepatocellular carcinoma (HCC) is a globally prevalent malignancy with high mortality and limited predictive biomarkers. The neutrophil-to-lymphocyte ratio (NLR), a systemic inflammation marker, has been proposed...
The Prevalence of Gastric Atrophy in Western and Northern European Populations: A Systematic Review and Meta-Analysis [0.03%]
西方和北欧人群中胃黏膜萎缩的流行病学特征：系统评价和 meta 分析
Eoghan Burke,Patricia Harkins,Mayilone Arumugasamy
Eoghan Burke
Background: Gastric atrophy (GA) is a pre-neoplastic condition leading to gastric cancer (GC). Early GA detection is critical for guiding surveillance and preventing advanced GC. Histology is the current gold standard for...
FOLFIRINOX vs. Gemcitabine Nab-Paclitaxel in Pancreatic Cancer: A Real-World Single-Center Analysis of Efficacy and Safety [0.03%]
一线接受FOLFIRINOX与吉西他滨联合白蛋白结合型紫杉醇治疗胰腺导管腺癌的疗效和安全性的真实世界研究：单中心分析
Arif Mohammed Khan,Vamshi Krishna Muddu,Naga Avinash Bonda et al.
Arif Mohammed Khan et al.
Background: Pancreatic cancer is among the most lethal malignancies, with limited real-world data comparing frontline chemotherapy regimens across disease stages. FOLFIRINOX and gemcitabine plus nab-paclitaxel (G + P) are...
Efficacy and Safety of Neoadjuvant Chemotherapy with or without Immune Checkpoint Inhibitors for Resectable Esophageal Squamous Cell Carcinoma: a Meta-analysis of Randomized Controlled Trials [0.03%]
新辅助化疗联合或不联合免疫检查点抑制剂治疗可切除食管鳞癌的疗效和安全性：随机对照试验的meta分析研究
Ting Zheng,Xingxing Li,Li Zhou et al.
Ting Zheng et al.
Background: Recently, there has been significant attention focused on neoadjuvant immune checkpoint inhibitors combined with chemotherapy (NICT) for the treatment of resectable esophageal squamous cell carcinoma (ESCC). I...
Effects of Sarcopenia on Patient Outcomes in Gastrointestinal Cancer: An Umbrella Review of Published Meta-Analyses [0.03%]
肌少症对胃肠肿瘤患者预后影响的伞式评价研究META分析
Camilo Ramírez-Giraldo,Luis Carlos Venegas-Sanabria,Antonio Pesce et al.
Camilo Ramírez-Giraldo et al.
Background: Gastrointestinal tumors represent a significant proportion of malignant neoplasms worldwide. Sarcopenia has emerged as a clinically relevant prognostic factor. Defined as the progressive and generalized loss o...
Systematic Analysis of the Differential Effects of Red Meat on Colorectal Cancer Risks: A Meta-Analytic Approach [0.03%]
系统分析红肉对结直肠癌风险的差异化影响：元分析方法
Jun Yu Woon,Gihani Vidanapathirana,Alfred K Lam et al.
Jun Yu Woon et al.
Objectives: Colorectal cancer (CRC) is the third most common cancer worldwide, with rising incidence in younger populations. Red meat consumption has been proposed as a risk factor for CRC, though the evidence remains inc...
Gallbladder Cancer and Peritoneal Metastasis: Is there any role of Cytoreductive Surgery (CRS) and/or Hyperthermic Intraperitoneal Chemotherapy (HIPEC)? A Narrative Review [0.03%]
胆囊癌和腹膜转移：减瘤术（CRS）和/或腹腔热灌注化疗(HIPEC)的作用如何？叙述性综述
Kailash Chand Kurdia,Vinay Kumar Kapoor
Kailash Chand Kurdia
Introduction: Gallbladder cancer (GBC) is the most common biliary tract cancer (BTC) worldwide-the majority of GBC patients present with locally advanced or metastatic disease. Peritoneum is one of the most common sites o...
Trends and Disparities in Mortality Due to Gastric Malignancies the United States: A Nationwide Analysis from 1999 to 2020 [0.03%]
1999至2020年美国胃恶性肿瘤死亡率变化及差异：基于全国性数据分析
Muhammad Ahmad,Aizaz Ali,Tahreem Mari et al.
Muhammad Ahmad et al.
Purpose: Gastric malignancies remain a significant public health concern and a major contributor to cancer-related mortality worldwide. This study aimed to analyze trends and disparities in gastric malignancy mortality ac...