Comparing Operative Outcomes and Resection Quality in Robotic vs Open Pancreaticoduodenectomy: A Meta-analysis of 54,000 Patients [0.03%]
荟萃分析：机器人胰十二指肠切除术与开腹胰十二指肠切除术的手术结果和切除质量对比（共54,000例患者）
Muhammad Hassan Waseem,Zain Ul Abideen,Rafia Durrani et al.
Muhammad Hassan Waseem et al.
Background: High morbidity and mortality make pancreaticoduodenectomy (PD) one of the most complicated surgical procedures. This meta-analysis aimed to compare the outcomes of robotic pancreaticoduodenectomy (RPD) versus ...
Makiko Kawano,Yoko Oshima,Fumiaki Shiratori et al.
Makiko Kawano et al.
Purpose: Basophils play a crucial role in immunoglobulin E-mediated allergic reactions and parasitic infections. Recently, a low basophil count was reported to be a poor prognostic indicator in patients with malignant tum...
Trends and Disparities in Intrahepatic Cholangiocarcinoma-related Mortality in the United States from 1999 to 2020 [0.03%]
1999至2020年美国肝内胆管癌死亡率的变化和差异
Obaid Ur Rehman,Malik Saad Hayat,Muhammad Mukarram Shoaib et al.
Obaid Ur Rehman et al.
Purpose: Intrahepatic cholangiocarcinoma (ICC) arises from the epithelial cells of the bile ducts present inside the liver parenchyma and is associated with an overall poor prognosis due to advanced disease stage at the t...
PI3K/AKT/mTOR Targeting in Colorectal Cancer Radiotherapy: A Systematic Review [0.03%]
磷脂酰肌醇-3-激酶/蛋白激酶B/哺乳动物雷帕霉素靶点在结直肠癌放射治疗中的作用：系统性综述
S N Mousavikia,L Darvish,A A Firouzjaei et al.
S N Mousavikia et al.
Background: Radioresistance is a major challenge in the treatment of patients with colorectal cancer (CRC) and impairs the efficacy of radiotherapy. The PI3K/AKT/mTOR signaling pathway plays a critical role in CRC and con...
Trends in Colorectal Cancer Peritoneal Metastases Research: A Comprehensive Bibliometric Analysis [0.03%]
结直肠癌腹膜转移研究趋势：全面的计量学分析
Yuzhe Zhang,Zi Jin,Zhongqing Wang et al.
Yuzhe Zhang et al.
Background: Colorectal cancer (CRC) stands as the third most prevalent malignancy globally and is recognized as the second leading cause of cancer-related mortality. Notably, nearly 50% of individuals diagnosed with CRC u...
A Review of Circulating Tumor DNA (ctDNA) in Pancreatic Cancer: Ready for the Clinic? [0.03%]
循环肿瘤DNA（ctDNA）在胰腺癌中的研究进展：准备应用于临床吗？
Purvi Jonnalagadda,Virginia Arnold,Benjamin A Weinberg
Purvi Jonnalagadda
Pancreatic ductal adenocarcinoma is a devastating disease which is associated with an increase in cancer-related death in the USA. The minority of patients are cured by surgery alone and typically require adjuvant chemotherapy in order to i...
Identification of Metabolic Characteristic-Pancreatic Ductal Adenocarcinoma Associations Using Mendelian Randomization and Metabolomics [0.03%]
利用孟德尔随机化和代谢组学鉴定代谢特征与胰腺导管腺癌关联性
Yaoxian Xiang,Chan Zhang,Jing Wang et al.
Yaoxian Xiang et al.
Background: Metabolic reprogramming is increasingly recognized as a crucial factor influencing the development, progression, and prognosis of pancreatic ductal adenocarcinoma (PDAC). Despite this, the potential associatio...
PD-1/PD-L1 Inhibitors Increase Pathological Complete Response in Locally Advanced Gastric Cancer: A Meta-analysis and Trial Sequential Analysis [0.03%]
程序性死亡受体1/配体1抑制剂可提高局部晚期胃癌病理完全缓解率：Meta分析与试验序贯分析
Francisco Cezar Aquino de Moraes,Vitor Kendi Tsuchiya Sano,Barbara Lins Silva et al.
Francisco Cezar Aquino de Moraes et al.
Background and objective: Gastric cancer (GC) remains a leading cause of morbidity and mortality worldwide. The current standard of care involves neoadjuvant chemotherapy (NACT) followed by radical gastrectomy. This study...
Evolving Paradigms in the Treatment of Oligometastatic Pancreatic Ductal Adenocarcinoma [0.03%]
寡转移胰腺导管腺癌治疗理念的演变
Enoch Chang,Alexander D Sherry,Jakob Liermann et al.
Enoch Chang et al.
Multiple randomized trials have suggested that the addition of comprehensive metastasis-directed therapy to best systemic therapy improves disease control and survival among patients with oligometastatic disease, even for histologies with a...
Preoperative Carcinoembryonic Antigen as a Predictor of 5-Year Survival in Rectal Cancer: Proposing a New Prognostic Cutoff [0.03%]
术前癌胚抗原预测直肠癌五年生存率的新临界值
Amir Keshvari,Seyed Mohsen Ahmadi Tafti,Mohammad Reza Keramati et al.
Amir Keshvari et al.
Purpose: Carcinoembryonic antigen (CEA) is an important prognostic factor for rectal cancer. This study aims to introduce a novel cutoff point for CEA within the normal range to improve prognosis prediction and enhance pa...