Advances and Challenges in the Application of Novel Oral Anticoagulants for Venous Thromboembolism Prevention Following Colorectal Cancer Surgery [0.03%]
新型口服抗凝药物在结直肠癌术后静脉血栓预防中的应用进展与挑战
Yang Kun,Zhao Song
Yang Kun
Background: Venous thromboembolism (VTE) is a common but severe complication following colorectal cancer (CRC) surgery. Traditional anticoagulants such as low molecular weight heparin (LMWH) and vitamin K antagonists face...
Homologous Recombination Deficiency Is Associated with Shorter Survival in Colorectal Cancer Patients [0.03%]
同源重组缺陷与结直肠癌患者生存期缩短有关
Xuan Zhang,Pan Zhang,Hua Dong et al.
Xuan Zhang et al.
Background: Colorectal cancer (CRC) patients benefit more from immune checkpoint inhibitor therapy, but they only account for around 15% of all patients. The remaining patients still lack effective therapeutic biomarkers ...
Immune-Based Therapies in Pancreatic Cancer: a Systematic Review of Ongoing Clinical Trials (2020-2022) [0.03%]
基于免疫的胰腺癌治疗的系统性回顾：临床试验（2020-2022）
Justine T Hung,Ritwick S Mynam,Monica A Patel et al.
Justine T Hung et al.
Introduction: Immune-based treatment strategies have emerged across solid organ malignancies largely with the development of immune checkpoint inhibitors. To date, these strategies have not improved clinical outcomes in p...
Effects of Palliative Esophageal External Beam Radiation Therapy in Patients with Stent for Esophageal Cancer: A Retrospective Cohort Study [0.03%]
食管癌置管患者的姑息性食管外照射疗效回顾队列研究
Emily Adams,Héloïse Lavoie-Gagnon,Farhana Islam et al.
Emily Adams et al.
Purpose: Self-expandable metallic stents (SEMS) provide immediate but nondurable dysphagia relief in esophageal cancer, while external beam radiotherapy (EBRT) provides slower, more durable dysphagia relief. While the com...
Surgical Resection Versus Microwave Ablation for Colorectal Liver Oligometastases: A Multicenter Cohort Study of 1027 Patients [0.03%]
colorectal liver寡转移灶的手术切除与微波消融效果比较：一项纳入1027例患者的多中心队列研究
Bin Li,Lei Li,He Ren
Bin Li
Background: The choice between surgical resection (SR) and microwave ablation (MWA) as first-line treatments that prolong survival duration for colorectal liver oligometastases (CRLOM) remains controversial. ...
Comparative Study
Journal of gastrointestinal cancer. 2025 Apr 17;56(1):101. DOI:10.1007/s12029-025-01222-y 2025
A Case Study on Complete Pathological Response in Advanced Rectal Cancer Patient with Oxaliplatin-based Chemotherapy without Cumulative Neurotoxicity [0.03%]
一例以奥沙利铂为基础的化疗获得完全病理学反应的晚期直肠癌患者且无累积神经毒性的病例研究
Rehab A M Jawad,Bahir Abdul-Razzaq Mshimesh,Qasim S Al-Mayah et al.
Rehab A M Jawad et al.
Background: The pathological response in rectal cancer treatment provides insight into the molecular mechanisms, including genetic alterations and signaling pathways that influence tumor behavior and resistance to treatme...
Identification of Novel Protein Biomarkers for Intrahepatic Cholangiocarcinoma by Integrating Human Plasma Proteome with Genome [0.03%]
整合人类血浆蛋白质组与基因组识别新的蛋白生物标志物以用于肝内胆管癌诊断
Yu-Sen Chen,Wei-Bang Yang,Yi-Hu Li et al.
Yu-Sen Chen et al.
Background: The proteome serves as a key source for the discovery of therapeutic targets. This study utilized proteome-wide Mendelian randomization (MR) to identify protein biomarkers potentially associated with intrahepa...
Supportive Care Needs and Related Interventions in Patients with Pancreatic Cancer and Their Informal Caregivers: A Scoping Review [0.03%]
胰腺癌患者及其非正式照顾者的支持性护理需求和相关干预措施的综述研究
Liang Fu,Su Hyun Kim,Deanna Dolores Garcia et al.
Liang Fu et al.
Purpose: This scoping review aims to provide a comprehensive literature review regarding supportive care needs and related interventions for patients with pancreatic cancer and/or their informal caregivers. ...
Regulatory T Cell Infiltration-Driven Single-Cell Transcriptomic Analysis Identifies SAP18 as a Prognostic Marker for Esophageal Squamous Cell Carcinoma [0.03%]
调节性T细胞浸润驱动的单细胞转录组分析鉴定SAP18作为食管鳞状细胞癌预后标志物
Jianxiang Huang,Hanshuo Zhang,Xinyue Lin et al.
Jianxiang Huang et al.
Background: Advanced esophageal squamous cell carcinoma (ESCC) is characterized by molecular heterogeneity and distinct patterns of immune cell infiltration. Regulatory T cells (Tregs), in particular, play a critical role...
FGFR as a Predictive Marker for Targeted Therapy in Gastrointestinal Malignancies: A Systematic Review [0.03%]
FGFR作为胃肠恶性肿瘤靶向治疗预测标记物的系统评价
Nika Seraji,Irina Berger
Nika Seraji
Background: Gastrointestinal (GI) cancers constitute approximately 25% of cancers worldwide. The fibroblast growth factor receptor (FGFR) family is a promising target for immunotherapy aiming to enhance survival rates. FG...