Bioinformatics Analysis Reveals the Role of DLGAP4 in the Development and Progression of Hepatocellular Carcinoma [0.03%]
生物信息学分析揭示DLGAP4在肝细胞癌发生发展中的作用
Feng Yang,Shoufeng Chang,Ruxia Li et al.
Feng Yang et al.
Purpose: Although the DLGAP4 gene is well-established in neurological disorders, its function in hepatocellular carcinoma (HCC) remains unclear. This study aims to characterize DLGAP4 expression patterns, prognostic signi...
Clinical Efficacy and Safety of Gemcitabine-Cisplatin Combination in Metastatic Gallbladder Cancer: A Prospective Study from North India [0.03%]
吉西他滨-顺铂新组合方案治疗胆囊癌转移的临床疗效和安全性：一项来自印度北部的研究
Abhinav Dewan,Vineet Talwar,Varun Goel et al.
Abhinav Dewan et al.
Background: Gemcitabine-cisplatin doublet is a standard first-line regimen for metastatic gallbladder cancer (GBC), though prospective real-world data remains scarce. We evaluated the efficacy, safety, and prognostic fact...
Re-evaluating Gastric Ulcer Re-evaluation: Low Malignancy Yield and High Cost in a 19-Year Retrospective Cohort Study [0.03%]
胃溃疡复查的再评价：19年回顾性队列研究中的低癌变率和高成本
Thomas Matthews,Mark Vesey,Aditya Billur et al.
Thomas Matthews et al.
Background: Routine endoscopic re-evaluation of gastric ulcers (GUs) is widely recommended to exclude malignancy. However, in modern practice, particularly in low-to-intermediate gastric cancer prevalence settings, the di...
Role of 18FDG PET-CT & MRI for Predicting Response to Neo-Adjuvant Therapy in Rectal Cancer [0.03%]
18FDG PET-CT及MRI在预测直肠癌新辅助治疗疗效中的作用
Kaushik Jaganathan,Shaifali Goel,Abhishek Aggarwal et al.
Kaushik Jaganathan et al.
Purpose: Neoadjuvant chemoradiotherapy (NACRT) is standard for locally advanced rectal cancer. Accurate response assessment is essential, particularly to identify complete responders eligible for organ-preserving strategi...
Radioembolization in Hepatocellular Carcinoma: Indications and Outcomes [0.03%]
放射性微球栓塞治疗肝细胞癌的指征和疗效研究进展
Bahareh Gholami,Ali Afrasiabi,Paolo Varela et al.
Bahareh Gholami et al.
Hepatocellular carcinoma (HCC) continues to rank among the most common causes of cancer-associated deaths, especially since a large number of patients cannot undergo curative resection or transplantation. For HCC patients, transarterial rad...
Local Recurrence Rates in Locally Advanced Rectal Cancer Are Higher with KRAS Codon 13 Mutations [0.03%]
KRAS第13密码子突变的局部进展期直肠癌局部复发率更高
Richard Sassun,Annaclara Sileo,Jyi Cheng Ng et al.
Richard Sassun et al.
Purpose: Despite advances in oncology regimens and standardization of technical approaches such as total mesorectal excision (TME), local recurrences (LR) remain a significant concern in rectal cancer. This may be due to ...
Prehabilitation Targets Associated with the Omission of Adjuvant Chemotherapy After Surgery for Pancreatic Cancer [0.03%]
手术治疗后遗漏辅助化疗与胰腺癌相关预康复目标的关系
N C Biesma,E Lemmens,G A Cirkel et al.
N C Biesma et al.
Introduction: Curative treatment for pancreatic cancer relies on surgical resection combined with systemic chemotherapy, administered either before (neoadjuvant) or after (adjuvant) surgery. However, a considerable propor...
Observational Study
Journal of gastrointestinal cancer. 2025 Nov 25;56(1):227. DOI:10.1007/s12029-025-01357-y 2025
Association of Spirometric Lung Age with Survival Outcomes in Elderly Patients Undergoing Radical Surgery for Gastric Cancer [0.03%]
肺功能实际年龄与胃癌根治手术老年患者生存结局的关系研究
Masayuki Urabe,Mami Suzuki,Takahiro Fukai et al.
Masayuki Urabe et al.
Background: The proportion of elderly patients among those diagnosed with gastric cancer (GC) is increasing worldwide. Given that physiological reserves are often diminished in this population, reliable tools for preopera...
Proton Pump Inhibitors Attenuate the Effectiveness of Nivolumab Monotherapy in Patients with Advanced Gastric Cancer: A Retrospective Study [0.03%]
质子泵抑制剂可减弱纳武利尤单抗单药治疗晚期胃癌患者的疗效：一项回顾性研究
Mikumi Yamaguchi,Hitoshi Kawazoe,Yusuke Kasai et al.
Mikumi Yamaguchi et al.
Purpose: This study aimed to investigate the effects of concomitant proton pump inhibitor (PPI) use on the effectiveness of nivolumab in Japanese patients with advanced gastric cancer. ...
Observational Study
Journal of gastrointestinal cancer. 2025 Nov 21;56(1):226. DOI:10.1007/s12029-025-01354-1 2025