The Landscape of Genomic Alterations in Receptor Tyrosine Kinase Pathways in Biliary Cancers: Implications for Targeted Therapies [0.03%]
受体酪氨酸激酶信号通路在胆系癌中的基因组改变及靶向治疗的临床应用研究现状与挑战
Ioannis A Voutsadakis
Ioannis A Voutsadakis
Background: Biliary carcinomas are aggressive cancers with a high mortality rate. When metastatic, biliary cancers are associated with a short survival and low response to treatments. The first line therapy of metastatic ...
Does Malignant Ascites Define Prognosis in Gastric Cancer with Peritoneal Spread? A Systematic Review and Meta-analysis [0.03%]
恶性的腹水能定义胃癌伴腹膜转移的预后吗？一项系统回顾及荟萃分析
Francisco Cezar Aquino de Moraes,Luis Henrique Rios Moreira Rego,Gustavo Tadeu Freitas Uchôa Matheus et al.
Francisco Cezar Aquino de Moraes et al.
Background: Gastric cancer (GC) is the fifth most common cancer and a leading cause of cancer-related death. Peritoneal metastases occur in up to 25% of patients, with nearly half developing malignant ascites (MA), which ...
Overcoming the Challenge: A Comprehensive Review of Neoadjuvant Treatment Resistance in Rectal Cancer [0.03%]
直肠癌新辅助治疗耐药的挑战及对策综述
Alexandru Micu,Andrei Diaconescu,Corina-Elena Minciuna et al.
Alexandru Micu et al.
Colorectal cancer (CRC) is the third most commonly diagnosed cancer and remains a leading cause of cancer-related mortality, particularly among younger men. Approximately one-third of colorectal cancers occur in the rectum. For patients wit...
Comparative Outcomes of Spleen Preservation and Splenectomy in Total Gastrectomy for Proximal Gastric Cancer: A Systematic Review and Meta-Analysis [0.03%]
全胃切除术治疗高位胃癌患者保脾与切脾的临床结局比较：系统评价和 meta 分析
Ana Luíza Rocha Soares Menegat,Brenda Luana Rocha Soares Menegat,Bárbara Corrêa Garcia Simões et al.
Ana Luíza Rocha Soares Menegat et al.
Objective: This systematic review and meta-analysis evaluated whether spleen-preserving surgery with gastrectomy reduces the risk of intra-and postoperative complications compared with splenectomy in patients with proxima...
Area Deprivation Index as a Predictor of Hepatocellular Carcinoma Prognosis: Limited Predictive Utility in an Integrated Care Model [0.03%]
地区剥夺指数对肝细胞癌预后的预测作用：综合护理模式下的有限预测效用
Avi Toiv,Hope B O&#x;Brien,Anqi Wang et al.
Avi Toiv et al.
Purpose: Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death worldwide, yet mortality outcomes in patients with HCC can vary widely. Socioeconomic disparities are known to influence health outcomes i...
Oligometastatic Gastric Cancer: Novel Considerations for Personalized Approach [0.03%]
寡转移性胃癌：个性化治疗的新考虑因素
Gerasimia D Kyrochristou,Georgios D Lianos,Ilektra D Kyrochristou et al.
Gerasimia D Kyrochristou et al.
Background: Metastatic disease traditionally classifies gastric cancer as stage M1, precluding surgical intervention and enrolling patients in palliative treatment protocols. This principle holds regardless of the number,...
Comparing ICG-Guided vs. Conventional Laparoscopic Lymphadenectomy in Gastric Cancer: A Systematic Review and Meta-Analysis [0.03%]
近红外荧光素靛氰绿指导与传统腹腔镜胃周淋巴结清扫的差异：系统回顾和 meta 分析
Abdullah Afridi,Maria Qadri,Fatima Sajjad et al.
Abdullah Afridi et al.
Background: Gastric cancer remains one of the leading causes of cancer-related mortality worldwide, with surgical intervention being a critical aspect of treatment. Lymphadenectomy plays a significant role in managing gas...
C. difficile Infection in Colorectal Cancer: Risk Determinants, Outcomes, and Evolving Management Approaches [0.03%]
难辨梭菌在结直肠癌患者中的感染危险因素、结局及管理措施的演变趋势
Mustafa Khalid AbdulJabbar,Susan Saab Manfi Al-Rawi,Bilal Khaleel Midhin et al.
Mustafa Khalid AbdulJabbar et al.
Background: Colorectal cancer (CRC) ranks as the third most prevalent cancer globally and poses a considerable public health challenge; concurrently, Clostridioides difficile infection (CDI) represents a significant hospi...
Primary Malignant Melanoma of the Oesophagus Treated With Immunotherapy: A Case Report and Scoping Review of the Literature [0.03%]
免疫治疗的一例原发性食管恶性黑色素瘤的病例报告和文献综述
Eve Hopping,Lauren Kennedy,Antonio Barbaro et al.
Eve Hopping et al.
Purpose: Primary malignant melanoma of the oesophagus is extremely rare. Given this, there is a paucity of evidence to guide treatment decisions. Traditionally, treatment has included standard modalities of surgery, chemo...
Do Incretin-Based Therapies Influence the Risk of Cholangiocarcinoma in Type 2 Diabetes Patients? Insights from a Systematic Review and Meta-Analysis [0.03%]
基于肠泌素的疗法会增加2型糖尿病患者的胆管癌风险吗？系统评价和Meta分析的新启示
Eric Ricardo Yonatan,Louis Fabio Jonathan Jusni,Steven Alvianto et al.
Eric Ricardo Yonatan et al.
Introduction: Incretin-based therapies, including glucagon-like peptide-1 receptor agonists (GLP-1RAs) and dipeptidyl peptidase-4 inhibitors (DPP-4Is), are widely used in the management of type 2 diabetes mellitus (T2DM)....