Differential associations of IgG-aFcεRI and IgG-aIgE autoantibodies with clinical phenotypes of type IIb chronic spontaneous urticaria [0.03%]
IgG-aFcεRI和IgG-aIgE自身抗体与IIb型自发性慢性荨麻疹临床表型的关联性研究
Lāsma Lapiņa,Stefan Frischbutter,Jween Mohammad et al.
Lāsma Lapiņa et al.
Background: Chronic spontaneous urticaria (CSU) is a common mast cell-driven skin disorder characterized by recurrent wheals and/or angioedema lasting more than 6 weeks. A subset of patients shows type IIb autoimmune feat...
Knowledge of chronic spontaneous urticaria management among Italian general practitioners: Baseline findings from the BRIDGE study [0.03%]
BRIDGE研究中的意大利全科医师对慢性自发性荨麻疹管理的认知：基线结果
Piergiacomo Calzavara-Pinton,Enrico Iemoli,Pallavi Saraswat et al.
Piergiacomo Calzavara-Pinton et al.
Introduction: Patients with chronic spontaneous urticaria (CSU) often experience diagnostic delays and uncontrolled disease, highlighting the need to improve CSU care. The BRIDGE study, a hybrid type 1 effectiveness-imple...
Rhizoma Dioscoreae Nipponicae attenuates airway remodeling and angiogenesis-related changes in asthma with altered mTOR/4EBP1/HIF-1α/VEGF pathway markers [0.03%]
地黄连根茎通过调节mTOR/4EBP1/HIF-1α/VEGF通路标记物改变来减轻哮喘相关气道重构和血管生成变化
Xiaoqing Zhou,Zhen Wang,Suqun Zheng
Xiaoqing Zhou
Background: Asthma is a chronic inflammatory airway disease characterized by airway remodeling and hyperresponsiveness. Angiogenesis is a key contributor to airway remodeling and disease progression. Rhizoma Dioscoreae Ni...
Olfactory mucosal inflammation and barrier disruption correlate with perceived CRSwNP-associated olfactory dysfunction [0.03%]
嗅觉黏膜炎症和屏障功能障碍与CRSwNP相关联的感知到的嗅觉功能障碍有关
Linghui Meng,Shengyang Liu,Peng Yu et al.
Linghui Meng et al.
Objective: This study aimed to characterize the local inflammatory and histopathological features of the olfactory mucosa (OM) in patients with CRSwNP and to clarify how these local changes are associated with perceived o...
Comparison of the efficacy of different doses of omalizumab (150 mg vs 300 mg) in patients with seasonal allergic rhinitis and low total IgE: A randomized, double-blind, controlled study [0.03%]
不同剂量奥马珠单抗（150毫克和300毫克）治疗低总IgE季节性过敏性鼻炎患者疗效的比较：随机、双盲、对照研究
Lisha Li,Yingyang Xu,Sainan Bian et al.
Lisha Li et al.
Objective: This study compares the efficacy of monthly subcutaneous injections of 150 mg versus 300 mg omalizumab in patients with seasonal allergic rhinitis (AR) caused by cypress pollen allergy and with total immunoglob...
Subcutaneous immunotherapy-induced IgG1 suppresses allergic airway inflammation through FcγRIIb-mediated inhibition of group 2 innate lymphoid cell proliferation [0.03%]
皮下免疫治疗诱导的IgG1通过FcγRIIb介导抑制组2固有淋巴样细胞增殖来抑制过敏性气道炎症
Masaya Matsuda,Asuka Hirano,Momo Morishita et al.
Masaya Matsuda et al.
Background: Subcutaneous immunotherapy (SCIT), a form of allergy immunotherapy, can alter the natural course of allergic diseases and induce tolerance to causative allergens by modulating type 2 immune responses. While th...
Clinical characteristics and IgE-binding protein profiles of patients with buckwheat allergy in China [0.03%]
中国荞麦过敏患者的临床特征及IgE结合蛋白谱型分析
Sainan Bian,Zhenjing Geng,Yanjun Zhou et al.
Sainan Bian et al.
Background: To characterize patients with buckwheat allergy in China and to investigate the associations between clinical manifestations and different buckwheat IgE-binding proteins. ...
Vitamin B12 desensitization and provocation: Ten-year clinical experience [0.03%]
维生素B12脱敏和激发治疗的十年临床经验
Fatma Dindar Çelik,Kurtuluş Aksu,Özge Göktürk et al.
Fatma Dindar Çelik et al.
Background: Vitamin B12 is an essential micronutrient and hypersensitivity reactions (HSR) are considered rare. Objective: To present t...
Response to reader comments on "clinical features of Hereditary Angioedema involving the gastrointestinal tract: A retrospective analysis" [0.03%]
“遗传性肠血管水肿的临床特征”读者来信回应
Haiyuan Ma,Danping Zheng,Baili Chen
Haiyuan Ma
Concurrent hereditary angioedema type I and common variable immunodeficiency presenting as suspected antibiotic hypersensitivity: Case report and literature discussion [0.03%]
遗传性血管水肿1型伴常见可变免疫缺陷症的并发病例报告及文献讨论：作为疑似抗生素过敏反应出现
Delia Urdea,Deniss V Mereuta,Raluca E Iorga et al.
Delia Urdea et al.
Hereditary angioedema (HAE) and common variable immunodeficiency (CVID) are rare disorders with heterogeneous clinical presentations that pose significant diagnostic challenges. HAE is characterized by recurrent episodes of subcutaneous or ...