Clinical remission in patients with severe eosinophilic asthma treated with benralizumab over 24 months: Post hoc analysis of the ANANKE study [0.03%]
利培珠单抗治疗重度嗜酸粒细胞哮喘患者24个月后达到临床缓解:ANANKE研究的事后分析
Giorgio Walter Canonica,Gianenrico Senna,Luisa Brussino et al.
Giorgio Walter Canonica et al.
Background: Clinical remission is an emerging treatment goal in severe eosinophilic asthma (SEA). While benralizumab, an anti-IL-5Rα monoclonal antibody, has demonstrated efficacy in SEA, its ability to induce clinical r...
Prevalence and risk factors of papular urticaria among school children in Cartagena, Colombia [0.03%]
哥伦比亚卡塔赫纳地区学龄儿童流行性丘疹性荨麻疹及危险因素
Josefina Zakzuk,Juliana Quintero,Devian Parra et al.
Josefina Zakzuk et al.
Introduction: Papular urticaria (PU) is a chronic allergic reaction to arthropod bites and is a common cause of pediatric dermatologic consultations in tropical regions. This study aimed to assess the prevalence and assoc...
Bronchiolitis and recurrent respiratory infections: The role of oxidative stress from early life inflammation to long-term outcomes - A narrative review [0.03%]
支气管炎和反复呼吸道感染:从早期生命炎症到长期结局的氧化应激作用——综述
Michele Piazza,Alessandra Gori,Carlo Capristo et al.
Michele Piazza et al.
Bronchiolitis, primarily caused by respiratory syncytial virus (RSV), is a common respiratory infection in infants and a known precursor to recurrent wheezing and asthma. This review explores the role of oxidative stress and trace element d...
Retrospective analysis of the efficacy and safety of 100 mg abrocitinib in patients with moderate to severe atopic dermatitis: Real-world study [0.03%]
艾罗西替尼治疗中重度特应性皮炎患者的疗效和安全性回顾性分析:真实世界研究
Maoying Li,Cuihong Lian,Xi Wang
Maoying Li
Objective: This study aimed to evaluate the real-world efficacy and safety of abrocitinib in Chinese patients with moderate to severe atopic dermatitis, while exploring the influence of prior dupilumab treatment on therap...
Early control or gradual relief? Gender-specific real-world insights into omalizumab response in chronic spontaneous urticaria patients [0.03%]
奥马珠单抗治疗慢性自发性荨麻疹患者早期控制与渐进缓解的性别差异及真实世界启示
Sarah Preis,Milena Lisiecki,Tilo Biedermann et al.
Sarah Preis et al.
Background: Chronic spontaneous urticaria (CSU) disproportionately affects women, yet gender-specific analyses in treatment response remain scarce. Real-world data on the impact of gender on omalizumab efficacy are limite...
Increased glucose transporter 1 contributes to epithelial barrier dysfunction in allergic rhinitis [0.03%]
过敏性鼻炎中葡萄糖转运蛋白1的上调参与上皮屏障功能障碍
Cui Xia,Kang Zhu,Chao Yu et al.
Cui Xia et al.
Background: Epithelial barrier impairment is a characteristic pathological hallmark of allergic rhinitis (AR), yet the mechanisms contributing to this dysfunction remain incompletely understood. Our aim is to assess the i...
Distinct treatment response trajectories to allergen immunotherapy in allergic asthma and rhinitis: Insights from a multicenter study in routine clinical practice [0.03%]
基于常规临床实践的多中心研究揭示了过敏性哮喘和变应性鼻炎免疫治疗反应的独特轨迹
Pingan Zhang,Rundong Qin,Weixi Zhang et al.
Pingan Zhang et al.
Background: While allergen-specific immunotherapy (AIT) is recognized as an effective treatment, its efficacy varies widely. However, whether clinical response trajectories to AIT differ among individuals and influence it...
Efficacy and acceptability of lanadelumab for long-term prophylaxis in hereditary angioedema: A Chinese multicenter real-world analysis [0.03%]
兰奥达用于遗传性血管水肿长期预防的有效性和可接受性:中国多中心真实世界研究分析
Yijing Xu,Ruoyu Ji,Juan Liu et al.
Yijing Xu et al.
Background: Hereditary angioedema (HAE) is a rare and potentially life-threatening genetic disorder. Lanadelumab, a monoclonal antibody inhibiting plasma kallikrein, has been approved for long-term prophylaxis (LTP) in HA...
The definition of asthma remission in children: A scoping review by the WAO Paediatric Asthma Committee [0.03%]
儿童哮喘缓解的定义:世界过敏组织儿科哮喘委员会的系统综述研究报告
Eleni Anastasiou,Michael Miligkos,Yuichi Adachi et al.
Eleni Anastasiou et al.
Background: Asthma remission has emerged as a potential therapeutic goal. However, definitions of remission have primarily focused on adult populations, with limited consensus on how remission should be defined in childre...
Characterization of Pana g 1, an important cause of pollen-food allergy syndrome from Korean ginseng, Panax ginseng [0.03%]
韩国人参(Panax ginseng)重要致敏原Pana g 1的鉴定
Kyoung Yong Jeong,Yoon Ji Shin,Haeun Kim et al.
Kyoung Yong Jeong et al.
Background: Ginseng is a widely consumed herbal supplement. However, ginseng, especially raw ginseng, can cause allergic reactions, including pollen-food allergy syndrome (PFAS). This study aimed to identify the PFAS-caus...