Energy bagging tree [0.03%]
能量装袋树
Taoyun Cao,Xueqin Wang,Heping Zhang
Taoyun Cao
This paper introduces Energy Bagging Tree (EBT) for multivariate nonparametric regression problems. The EBT makes use of a measure of dispersion constructed from a generalized Gini's mean difference as node impurity, and the tree split func...
Modeling Multiple Responses via Bootstrapping Margins with an Application to Genetic Association Testing [0.03%]
利用边际自助法建模多重响应及在基因关联性检验中的应用
Jiwei Zhao,Heping Zhang
Jiwei Zhao
The need for analysis of multiple responses arises from many applications. In behavioral science, for example, comorbidity is a common phenomenon where multiple disorders occur in the same person. The advantage of jointly analyzing multiple...
Genotype-based association models of complex diseases to detect gene-gene and gene-environment interactions [0.03%]
基于基因型的复杂疾病关联模型以检测基因-基因和基因-环境互作
Iryna Lobach,Ruzong Fan,Prashiela Manga
Iryna Lobach
A central problem in genetic epidemiology is to identify and rank genetic markers involved in a disease. Complex diseases, such as cancer, hypertension, diabetes, are thought to be caused by an interaction of a panel of genetic factors, tha...
Hongtu Zhu,Joseph G Ibrahim,Qingxia Chen
Hongtu Zhu
We establish a connection between Bayesian case influence measures for assessing the influence of individual observations and Bayesian predictive methods for evaluating the predictive performance of a model and comparing different models fi...
A cross-population extended haplotype-based homozygosity score test to detect positive selection in genome-wide scans [0.03%]
一种基于跨人群扩增单体型的杂合度检验的正向选择检测方法
Ming Zhong,Yiwei Zhang,Kenneth Lange et al.
Ming Zhong et al.
In this article, we developed a cross-population comparison test statistic to detect chromosome regions in which there is no significant excess homozygosity in one population but homozygosity remains high in the other. We treated an extende...
Estimating the Sizes of Populations At Risk of HIV Infection From Multiple Data Sources Using a Bayesian Hierarchical Model [0.03%]
利用贝叶斯分层模型从多个数据源估计面临HIV感染风险的人群规模
Le Bao,Adrian E Raftery,Amala Reddy
Le Bao
In most countries in the world outside of sub-Saharan Africa, HIV is largely concentrated in sub-populations whose behavior puts them at higher risk of contracting and transmitting HIV, such as people who inject drugs, sex workers and men w...
Coordinate great circle descent algorithm with application to single-index models [0.03%]
应用于单指标模型的协同大圆下降算法
Peng Zeng,Yichao Wu
Peng Zeng
Coordinate descent algorithm has been widely used to solve high dimensional optimization problems with a non-differentiable objective function recently. To provide theoretical justification, Tseng (2001) showed that it leads to a stationary...
A note on the relationships between multiple imputation, maximum likelihood and fully Bayesian methods for missing responses in linear regression models [0.03%]
多重插补、最大似然和完全贝叶斯方法在回归模型中的缺失响应关系注记
Qingxia Chen,Joseph G Ibrahim
Qingxia Chen
Multiple Imputation, Maximum Likelihood and Fully Bayesian methods are the three most commonly used model-based approaches in missing data problems. Although it is easy to show that when the responses are missing at random (MAR), the comple...
Accounting for linkage disequilibrium in genome-wide association studies: A penalized regression method [0.03%]
一种用于全基因组关联研究的惩罚回归方法考虑了连锁不平衡性
Jin Liu,Kai Wang,Shuangge Ma et al.
Jin Liu et al.
Penalized regression methods are becoming increasingly popular in genome-wide association studies (GWAS) for identifying genetic markers associated with disease. However, standard penalized methods such as LASSO do not take into account the...
Approximating the Geisser-Greenhouse sphericity estimator and its applications to diffusion tensor imaging [0.03%]
Geisser-Greenhouse球面对角形估计的近似及其在扩散张量成像中的应用
Meagan E Clement-Spychala,David Couper,Hongtu Zhu et al.
Meagan E Clement-Spychala et al.
The diffusion tensor imaging (DTI) protocol characterizes diffusion anisotropy locally in space, thus providing rich detail about white matter tissue structure. Although useful metrics for diffusion tensors have been defined, statistical pr...