Hearing Impairment and Cognitive Function: Mediating Role of Social Isolation and Depression [0.03%]
听力障碍与认知功能：社会隔离和抑郁症的中介作用
Fan Wu,Chenxi Zhou
Fan Wu
ObjectivesTo examine the relationship between hearing impairment and cognitive function and the mediating role of social isolation and depression. Methods: Data came from the 2018 China Health and Retirement Longitudinal Study wave. A self-...
Neuropsychiatric Behavioral Assessments in Mice After Acute and Long-Term Treatments of Low-Intensity Pulsed Ultrasound [0.03%]
低强度脉冲超声对小鼠进行急性及长期治疗后神经精神行为评估研究
Ye Li,Yiqing Wu,Qi Luo et al.
Ye Li et al.
Introduction: To evaluate whether both acute and chronic low-intensity pulsed ultrasound (LIPUS) affect brain functions of healthy male and female mice. Methods: Ultrasound (frequency: 1.5 MHz; pulse: 1.0 kHz; spatial average temporal avera...
Serum Protein-Based Profiles for the Diagnostic Model of Alzheimer's Disease [0.03%]
基于血清蛋白的阿尔茨海默病诊断模型特征研究
Li Yang,Liang He,Zhibin Bu et al.
Li Yang et al.
Background: Determining a non-invasive, serum-based diagnostic panel for early diagnosis of AD will play a significant role in the prevention and treatment of the disease. ...
A 12-Year Comparison of Alzheimer's Dementia Patients With Their Informants in Taiwan [0.03%]
台湾痴呆症患者及其照顾者的12年比较研究
Kai-Ming Jhang,Wen-Fu Wang,Kuang-Nan Hsu et al.
Kai-Ming Jhang et al.
Background: To update the characteristics of patients with Alzheimer's disease (AD) and their informants in Taiwan and compare them from 12 years ago. Met...
Lee Wolff,Yixue Quan,Gemma Perry et al.
Lee Wolff et al.
Music engagement is a ubiquitous activity that is thought to have cognitive benefits for the rapidly aging population. In the absence of robust treatment approaches for many age-related and neuropathological health issues, interest has emer...
Aerobic Treadmill Exercise Upregulates Epidermal Growth Factor Levels and Improves Learning and Memory in d-galactose-Induced Aging in a Mouse Model [0.03%]
有氧跑台运动通过上调表皮生长因子水平改善D-半乳糖衰老模型小鼠的学习记忆能力
Cheng Guo,Xiaoyang Kong,Yongzhao Fan et al.
Cheng Guo et al.
Previous studies have demonstrated that exercise improves cognitive function in Alzheimer's disease mice but the exact mechanism needs further studies. This research aimed to study the effects of aerobic treadmill exercise on epidermal grow...
The Neuropathological Impacts of COVID-19: Challenges and Alternative Treatment Options for Alzheimer's Like Brain Changes on Severely SARS-CoV-2 Infected Patients [0.03%]
Covid-19的神经病理影响：针对严重感染Sars-Cov-2患者的阿尔茨海默类脑变化的挑战及替代治疗方案
Md Rashidur Rahman,Raushanara Akter,Sharmind Neelotpol et al.
Md Rashidur Rahman et al.
Recently, some researchers claimed neuropathological changes lead to Alzheimer's-like brains after severe infection of SARS-CoV-2. Several mechanisms have been postulated on how SARS-CoV-2 neurological damage leads to Alzheimer's disease (A...
Intervention and Prevention of Dementia in the Greater Bay Area (GBA) of China [0.03%]
中国大湾区痴呆干预和预防项目
Brendan Weekes,Maria Teresa Carthery-Goulart
Brendan Weekes
Reserve and resilience are recognized as essential for effective intervention and prevention of dementia. However, it is not known if these factors also protect against risk for dementia in the Greater Bay Area (GBA) of Mainland China. Stud...
The Protective Effect of IDO1 Inhibition in Aβ-Treated Neurons and APP/PS1 Mice [0.03%]
IDO1抑制在Aβ处理的神经元和APP/PS1小鼠中的保护作用
Zhenzhen Duan,Lei Shi,Zhen Ning Tony He et al.
Zhenzhen Duan et al.
Alzheimer's disease (AD) is an inflammatory associated disease, in which dysregulated kynurenine pathway (KP) plays a key role. Through KP, L-tryptophan is catabolized into neurotoxic and neuroprotective metabolites. The overactivation of i...
Measurement of Five Emotions Defined by Traditional Chinese Medicine With a Focus on Preventing Mild Cognitive Impairment [0.03%]
基于中医五志理论的轻度认知障碍易患人群的情绪特征研究
Xiaoyu Wu,Jiaojiao Zou,Ziqiu He et al.
Xiaoyu Wu et al.
Objectives: This study aimed to develop a novel Measurement of the Five Emotions (MFE) based on traditional Chinese medicine for assessing cognitive impairment in elderly individuals. Methods: Surveys were collected from 184 participants, o...