Traditional and Non-traditional Caregivers Define "Family" and Caregiving Obligations [0.03%]
传统看护者和非传统的看护者定义“家庭”以及看护义务的方式
Sarah E Patterson,Kelsi Caywood,Samantha M Pantelic et al.
Sarah E Patterson et al.
Narrow definitions of family can constrain survey items about obligations regarding who should care for older adults. Current measurement often does not account for the increased prevalence of diverse family forms and support received among...
Restoration of Memory Along With Neurogenic Enhancement by Therapeutic Botulinum Neurotoxin in a Preclinical Model of Parkinson's Disease [0.03%]
肉毒杆菌毒素改善帕金森病的临床前模型中的神经发生及记忆恢复机制研究
Jerly Helan Mary Joseph,Mahesh Kandasamy
Jerly Helan Mary Joseph
Parkinson's disease (PD) is characterized by degeneration of dopaminergic neurons in the substantia nigra (SN), leading to motor impairments, while hippocampal dysfunction contributes to memory deficits. Botulinum neurotoxin (BoNT), a thera...
Predicting and Evaluating Cognitive Status in Aging Populations Using Decision Tree Models [0.03%]
基于决策树模型的老年群体认知状态的预测与评估
Zhidi Luo,Stella Ping Wang,Emily H Ho et al.
Zhidi Luo et al.
Objective: To improve the identification of cognitive impairment by distinguishing normal cognition (NC), mild cognitive impairment (MCI), and Alzheimer's disease (AD). Methods: A recursive partitioning tree model was developed using ARMADA...
Alzheimer's Disease Dementia Prevalence in the United States: A County-Level Spatial Machine Learning Analysis [0.03%]
美国阿尔茨海默病痴呆症的县水平空间机器学习分析
Abolfazl Mollalo,George Grekousis,Hermes Florez et al.
Abolfazl Mollalo et al.
A growing body of literature has examined the impact of neighborhood characteristics on Alzheimer's disease (AD) dementia, yet the spatial variability and relative importance of the most influential factors remain underexplored. We compiled...
Risk Factors Profile in Dementia Patients at a Tertiary Care Hospital in Nepal: A Cross-Sectional Study [0.03%]
尼泊尔三级护理医院痴呆患者的风险因素特征：一项横断面研究
Omkar Dhungel,Pawan Sharma,Nidesh Sapkota
Omkar Dhungel
Dementia is attributable to 12 known risk factors in 40% cases. This study aimed to assess the prevalence of defined risk factors among people living with dementia. 174 patients with dementia and caregivers were interviewed using semi-struc...
Automatic Detection of Cognitive Impairment in Patients With White Matter Hyperintensity Using Deep Learning and Radiomics [0.03%]
利用深度学习和放射组学实现含脑白质高信号患者认知障碍的自动检测
Junbang Feng,Xingyan Le,Li Li et al.
Junbang Feng et al.
White matter hyperintensity (WMH) is associated with cognitive impairment. In this study, 79 patients with WMH from hospital 1 were randomly divided into a training set (62 patients) and an internal validation set (17 patients). In addition...
Study on Effect of Different Pulses of rTMS on Visual Working Memory in Elderly With SCD [0.03%]
不同脉冲频率的经颅磁刺激对轻度认知损伤老人视觉工作记忆的影响研究
Liu Meng,Ren-Ren Li,Zhang Wei et al.
Liu Meng et al.
Previous research has shown that rTMS improves visual working memory (VWM) performance in older people with subjective cognitive decline (SCD). However, the influence of stimulation parameters on the effect is unclear. We focus on the total...
Birth Rate as a Determinant of Dementia Incidence: A Comprehensive Global Analysis [0.03%]
生育率与痴呆症发病率关系的全球综合分析
Wenpeng You
Wenpeng You
Background: The role of parity in predicting dementia risk in women is debated. This study examines how birth rate affects global dementia incidence. Meth...
Shruti Sharma,Christina Ilse,Kiri Brickell et al.
Shruti Sharma et al.
Timely diagnosis of young-onset dementia (YOD) is critical. This study aimed to identify factors that increased time to diagnosis at each stage of the diagnostic pathway. Participants were patients diagnosed with YOD (n = 40) and their care...
Heart Rate and its Variability From Short-Term ECG Recordings as Potential Biomarkers for Detecting Mild Cognitive Impairment [0.03%]
心率和短期心电图记录的心率变异性作为检测轻度认知障碍潜在生物标志物的潜力
Anjo Xavier,Sneha Noble,Justin Joseph et al.
Anjo Xavier et al.
Background: Alterations in Heart Rate (HR) and Heart Rate Variability (HRV) reflect autonomic dysfunction associated with neurodegeneration making them biomarkers suitable for detecting Mild Cognitive Impairment (MCI). Methods: The study in...