Value of Personalized Dementia-Specific Quality of Life Scales: An Explorative Study in 3 European Countries [0.03%]
欧洲三国针对痴呆症的个性化生存质量评价体系探索性研究价值分析
Iris Hendriks,Raquel Demetrio,Franka J M Meiland et al.
Iris Hendriks et al.
Measuring Quality of Life (QOL) can be difficult due to its individual character. To explore the value of personalized QOL measurement for people with dementia, personalized versions of two dementia-specific QOL scales (Dementia quality of ...
Neuropsychiatric Symptoms in Patients With Alzheimer's Disease During SARS-COV-2 Pandemic in Peru [0.03%]
疫情期间秘鲁阿尔茨海默病患者的精神行为症状病理学变化
Nilton Custodio,Sheila Castro-Suárez,Rosa Montesinos et al.
Nilton Custodio et al.
To evaluate neuropsychiatric symptoms in patients with Alzheimer's disease (AD) and their association with cognition and functionality during lockdown of the COVID-19's first wave. We included 91 patients and caregivers of people with AD fr...
Mechanism of Autonomic Exercise Improving Cognitive Function of Alzheimer's Disease by Regulating lncRNA SNHG14 [0.03%]
自主运动通过调控长链非编码RNA SNHG14改善阿尔茨海默病认知功能的机制研究
Yuchen He,Yi Qiang
Yuchen He
This paper studied the influence of exercise on the cognitive ability of AD patients and elucidated potential mechanisms. The expression of SNHG14 was validated by qRT-PCR. The cognitive impairment of mice was examined by MWM Test. ELISA te...
Preliminary Validation of the Triana Test: A New Story Recall Test Based on Emotional Material [0.03%]
基于情感材料的新故事回忆测验Triana检验的初步验证
Andrea Luque-Tirado,Silvia Rodrigo-Herrero,María Bernal Sánchez-Arjona et al.
Andrea Luque-Tirado et al.
Objective: To first validate the diagnostic accuracy of the "Triana Test," a new story recall test based on emotional material. Method: ...
Oral Amylin Treatment Reduces the Pathological Cascade of Alzheimer's Disease in a Mouse Model [0.03%]
舌下给予AMY治疗可减少阿尔茨海默病小鼠模型的病理进程
Hana Na,Hua Tian,Zhengrong Zhang et al.
Hana Na et al.
Intraperitoneal injection of amylin or its analog reduces Alzheimer's disease (AD) pathology in the brains. However, self-injecting amylin analogs is difficult for patients due to cognitive deficits. This work aims to study the effects of a...
MiR-130a-3p Has Protective Effects in Alzheimer's Disease via Targeting DAPK1 [0.03%]
MiR-130a-3p通过靶向DAPK1在阿尔茨海默病中发挥保护作用
Yanbo Wang,Min Shi,Zhenmei Hong et al.
Yanbo Wang et al.
The present study investigated the role and potential mechanisms of miR-130a-3p in AD. SH-SY5Y cells were treated with Aβ 1-42 to construct AD cell models. APP/PS1 mice were used for the animal experiments. MiR-130a-3p was downregulated in...
Liu Lu,Wen-Zhuo Dai,Xi-Chen Zhu et al.
Liu Lu et al.
This paper was aimed to analyze the microRNA (miRNA) signatures in Alzheimer disease (AD) and find the significant expressions of miRNAs, their target genes, the functional enrichment analysis of the confirmed genes, and potential drug trea...
Clinical Markers May Identify Patients at Risk for Early Parkinson's Disease Dementia: A Prospective Study [0.03%]
临床标志物或可识别早发帕金森病痴呆患者的危险因素：一项前瞻性研究
Anamaria Jurcau,Vharoon Sharma Nunkoo
Anamaria Jurcau
Background: The study aims at identifying features predictive of early onset of dementia in Parkinson's disease (PD). Methods: 103 non-...
Incidence of Mild Cognitive Impairment, Conversion to Probable Dementia, and Mortality [0.03%]
轻度认知障碍的发病率、可能痴呆的转化率和死亡率
Yun Zhang,Ginny Natale,Sean Clouston
Yun Zhang
Background: Few studies have jointly estimated incidence of MCI, conversion to probable dementia, and mortality in a nationally representatie sample. Meth...
The Role of Cilostazol and Inflammation in Cognitive Impairment After Ischemic Stroke [0.03%]
西洛他唑和炎症在缺血性卒中后认知障碍中的作用
Ling-Chun Huang,Sun-Wung Hsieh,Chia-Chan Tsai et al.
Ling-Chun Huang et al.
Purpose: The aim of this study is to examine the potential effect of cilostazol and inflammation on cognitive impairment after stroke in an Asian population. ...