Urinary AD7c-NTP Evaluates Cognition Impairment and Differentially Diagnoses AD and MCI [0.03%]
尿AD7c-NTP评估认知损害及鉴别诊断阿尔茨海默病和轻度认知障碍
Ming-Ran Xu,Rong-Fang Dai,Qing-Qi Wei et al.
Ming-Ran Xu et al.
The AD7c-NTP is a promising biomarker for AD diagnosis. However, the exact urinary AD7c-NTP concentration to differentiate AD from the mild cognitive impairment (MCI) remains inconclusive. We enrolled 98 and 90 clinical defined AD and MCI p...
Progesterone Receptor Membrane Component-1 May Promote Survival of Human Brain Microvascular Endothelial Cells in Alzheimer's Disease [0.03%]
孕酮受体膜成分-1可能通过阿尔茨海默病患者的血脑屏障内皮细胞存活起作用
Xin Xu,Xiangyan Ruan,Rui Ju et al.
Xin Xu et al.
Cerebrovascular changes occur in Alzheimer's disease (AD). The progesterone receptor membrane component-1 (PGRMC1) is a well identified hormone receptor with multiple functions in AD. This study aims to explore the involvement of PGRMC1 in ...
A Functional Assessment Tool to Distinguish Controls From Alzheimer's Disease in Lima, Peru [0.03%]
一种功能评估工具可将秘鲁利马的正常人与阿尔茨海默病患者区分开来
Nilton Custodio,Rosa Montesinos,Diego Chambergo-Michilot et al.
Nilton Custodio et al.
Background: The Alzheimer's Disease Cooperative Study-Activities of Daily Living (ADCS-ADL) scale is a versatile functional assessment tool for patients with Alzheimer's disease (ad). We evaluated its performance in contr...
Bilingualism as a Contributor to Cognitive Reserve: What it Can do and What it Cannot do [0.03%]
双语主义作为认知储备的贡献因素：它能做什么以及不能做什么
Matthias Berkes,Ellen Bialystok
Matthias Berkes
In the absence of effective pharmacological interventions for the prevention of dementia, attention has turned to lifestyle factors that contribute to cognitive reserve. Although cognitive reserve cannot prevent the occurrence of disease, t...
Validation of Picture Free and Cued Selective Reminding Test for Illiteracy in Lima, Peru [0.03%]
秘鲁首都利马文盲人群画面对应选择性提醒测试的有效性评估
Rosa Montesinos,Jose F Parodi,Monica M Diaz et al.
Rosa Montesinos et al.
Dementia in Latin America is a crucial public health problem. Identifying brief cognitive screening (BCS) tools for the primary care setting is crucial, particularly for illiterate individuals. We evaluated tool performance characteristics ...
The Involvement of lncRNA HOTAIR/miR-130a-3p Axis in the Regulation of Voluntary Exercise on Cognition and Inflammation of Alzheimer's Disease [0.03%]
长链非编码RNA HOTAIR/miR-130a-3p轴在自愿运动调节阿尔茨海默病认知和炎症中的作用
Jianxia Lu,Lihua Liu,Jin Chen et al.
Jianxia Lu et al.
Background: Alzheimer's disease (AD) is an age-related neurodegenerative disease and exercises might mitigate the progression of AD. This investigation aimed to manifest the potential mechanism of exercises in AD. ...
Emotion Processing Dysfunction in Alzheimer's Disease: An Overview of Behavioral Findings, Systems Neural Correlates, and Underlying Neural Biology [0.03%]
阿尔茨海默病情绪处理障碍：行为发现、系统神经相关及潜在神经生物学研究综述
Shefali Chaudhary,Simon Zhornitsky,Herta H Chao et al.
Shefali Chaudhary et al.
We described behavioral studies to highlight emotional processing deficits in Alzheimer's disease (AD). The findings suggest prominent deficit in recognizing negative emotions, pronounced effect of positive emotion on enhancing memory, and ...
Different Exercise Time on 5-HT and Anxiety-like Behavior in the Rat With Vascular Dementia [0.03%]
不同运动时间对血管性痴呆大鼠5-ht及焦虑样行为的影响
Yongzhao Fan,Linlin Zhang,Xiaoyang Kong et al.
Yongzhao Fan et al.
Background: Previous studies have demonstrated that pre-exercise suppresses anxiety-like behavior, but the effects of different exercise times on vascular dementia induced anxiety-like behavior have not been well investig...
Using a Non-Wearable Actigraphy in Nursing Care for Dementia With Lewy Bodies [0.03%]
在利-施耶兹体痴呆照护中使用非可穿戴活动节律计測仪
Chiaki Fukuda,Yoko Higami,Kazue Shigenobu et al.
Chiaki Fukuda et al.
People who have dementia with Lewy bodies often have sleep disorders. We used non-wearable devices to record and categorize the sleep patterns of patients with Lewy body dementia. Individual sleep data at a dementia-care unit in Japan were ...
Regulation of the Late Onset alzheimer's Disease Associated HLA-DQA1/DRB1 Expression [0.03%]
迟发型阿尔茨海默病相关HLA-DQA1 / DRB1表达的调节
Xiaoyu Zhang,Meijaun Zou,Yuwei Wu et al.
Xiaoyu Zhang et al.
(Genome-wide Association Studies) GWAS have identified ∼42 late-onset Alzheimer's disease (LOAD)-associated loci, each of which contains multiple single nucleotide polymorphisms (SNPs) in linkage disequilibrium (LD) and most of these SNPs ...