Quality-Adjusted Survival with Ribociclib Plus Fulvestrant Versus Placebo Plus Fulvestrant in Postmenopausal Women with HR±HER2- Advanced Breast Cancer in the MONALEESA-3 Trial [0.03%]
MONALEESA-3研究中瑞博西利联合氟维司群对比安慰剂联合氟维司群后线治疗HR阳性/HER2阴性绝经后晚期乳腺癌患者的质量调整生存分析
Guy Jerusalem,Thomas E Delea,Migule Martin et al.
Guy Jerusalem et al.
Background: MONALEESA-3 demonstrated an overall survival (OS) benefit for ribociclib plus fulvestrant (R+F) in postmenopausal women with hormone receptor (HR) positive, HER2 negative advanced breast cancer (ABC). This stu...
Clinical Trial
Clinical breast cancer. 2022 Jun;22(4):326-335. DOI:10.1016/j.clbc.2021.12.008 2022
An Update on the Molecular and Clinical Characteristics of Apocrine Carcinoma of the Breast [0.03%]
apocrine乳腺癌的分子和临床特征的最新研究进展
Semir Vranic,Zoran Gatalica
Semir Vranic
Apocrine carcinoma of the breast is a rare malignancy. According to 2019 WHO classification, apocrine cellular features and a characteristic steroid receptor profile (Estrogen receptor (ER)-negative and androgen receptor (AR)-positive) defi...
Factors Associated With Hospitalization Among Breast Cancer Patients With COVID-19: A Diverse Multi-Center Los Angeles Cohort Study [0.03%]
与乳腺癌患者新冠住院相关的因素：一项多元的洛杉矶多中心队列研究
Nikhita Kathuria-Prakash,Lauren Antrim,Nicholas Hornstein et al.
Nikhita Kathuria-Prakash et al.
Background: The SARS-CoV-2 virus has infected and killed millions of people worldwide. Breast cancer is the most prevalent cancer in women and few studies have investigated the outcomes of patients with a history of breas...
Physical Activity Levels of Breast Cancer Patients Before Diagnosis Compared to a Reference Population: A Cross-Sectional Comparative Study [0.03%]
乳腺癌患者诊断前体育锻炼水平与普通人群的对比研究：横断面比较性研究
An De Groef,Heleen Demeyer,Carlijn de Kinkelder et al.
An De Groef et al.
Purpose: We hypothesize that prediagnosis physical activity (PA) levels of breast cancer patients are below those of a reference population without breast cancer. Therefore, the aim of the present study was to compare pre...
Detailed Morphologic Evaluation of Breast Papillary Lesions on Core Biopsy Is Critical for Accurate Classification and Clinical Management: The Experience of an Academic Institute [0.03%]
细针穿刺活检乳腺乳头状病变的详细形态学评估对准确分类和临床治疗至关重要：学术机构的经验总结
Amber Petrolla,David G Hicks,Kristin A Skinner et al.
Amber Petrolla et al.
Background: Distinguishing between a breast intraductal papilloma and a papillary lesion with atypia or malignancy can be very challenging on core biopsy. There has been a long ongoing debate over whether or not it is nec...
Beta-2 Adrenergic Receptor Gene Expression in HER2-Positive Early-Stage Breast Cancer Patients: A Post-hoc Analysis of the NCCTG-N9831 (Alliance) Trial [0.03%]
一项关于NCCTG-N9831（联盟）试验中HER2阳性早期乳腺癌患者β2肾上腺素能受体基因表达的探索性分析
Rafael Caparica,Yaohua Ma,Claudia De Angelis et al.
Rafael Caparica et al.
Background: Beta-2 adrenergic receptor (ß2AR) modulates immune activation and may enhance trastuzumab activity. We assessed the impact of ß2AR gene (ADRB2) expression on the outcomes of patients with HER2-positive early...
Clinical Trial
Clinical breast cancer. 2022 Jun;22(4):308-318. DOI:10.1016/j.clbc.2021.11.012 2022
Metabolic Syndrome and Risk of Breast Cancer by Molecular Subtype: Analysis of the MEND Study [0.03%]
代谢综合征与乳腺癌分子亚型发病风险的关系——MENd研究分析
Tomi Akinyemiju,Taofik Oyekunle,Omolola Salako et al.
Tomi Akinyemiju et al.
Background: Metabolic syndrome (MetS) is characterized by a cluster of biological irregularities. The purpose of this analysis was to examine the association of MetS with BC among Nigerian women, and for the first time ev...
Determinants of Breast-Conserving Therapy in Early-Stage Breast Cancer Patients: A Nationwide Study [0.03%]
保乳治疗早中期乳腺癌患者的决定因素——一项全国性研究
Maria Paz Galeano Machuca,Wen-Ching Wu,Ben-Long Yu et al.
Maria Paz Galeano Machuca et al.
Introduction: Evidence from previous studies and treatment guidelines suggested that breast-conserving therapy (BCT) is the treatment of choice for early-stage breast cancer. However, in the last decades, surgeons have no...
Jakob H Viuff,Iben K Greiber,Mona Aa Karlsen et al.
Jakob H Viuff et al.
Introduction: Pregnancy rarely coincides with breast cancer, but when it does, uncertainties remain about how survival is affected. In a nation-wide study, we investigated survival in women diagnosed with breast cancer du...
Combination of Neutrophil-to-Lymphocyte Ratio and Red Cell Distribution Width With Serum Tumor Markers for the Differential Diagnosis of Breast Cancer and its Association With Pathological Features and Molecular Types [0.03%]
中性粒细胞与淋巴细胞比率及红细胞分布宽度联合血清肿瘤标志物鉴别乳腺癌的价值及其与病理特征和分子分型的关系
Hong Zou,Shu-Han Liu,Rong Yang et al.
Hong Zou et al.
Objective: To explore the neutrophil-to-lymphocyte ratio (NLR), red cell distribution width (RDW) and serum tumor markers as differential diagnostic markers of breast cancer (BC) and breast fibroadenoma (FA) and their ass...