An individual participant data meta-analysis of breast cancer detection and recall rates for digital breast tomosynthesis versus digital mammography population screening [0.03%]
数字乳房断层摄影术与数字化乳腺钼靶摄影人群筛查的乳腺癌检出率和征召回率的个体患者数据meta分析
Sol Libesman,Sophia Zackrisson,Solveig Hofvind et al.
Sol Libesman et al.
Background: Although digital breast tomosynthesis (DBT) improves breast cancer screen-detection compared to digital mammography (DM), there is less evidence on comparative screening outcomes by age and breast density, and...
The Cardioprotective Effect of Vitamin D in Breast Cancer Patients Receiving Adjuvant Doxorubicin Based Chemotherapy [0.03%]
维生素D对接受多柔比星化疗乳腺癌患者心脏保护作用的影响
Noha A El-Bassiouny,Maged W Helmy,Mostafa Alaa Eldin Hassan et al.
Noha A El-Bassiouny et al.
Purpose: The primary objective of this study was to investigate the potential protective effect of Vitamin D (Vit D) on DOX induced cardio toxicity (DIC) in early breast cancer patients receiving adjuvant DOX based chemot...
Randomized Controlled Trial
Clinical breast cancer. 2022 Jun;22(4):359-366. DOI:10.1016/j.clbc.2022.01.008 2022
The Interaction of NTN4 and miR-17-92 Polymorphisms on Breast Cancer Susceptibility in a Chinese Population [0.03%]
中国人群NTN4基因和miR-17-92多态性与乳腺癌易感性的关联分析
Yi-Shan Wang,Rong Guo,De-Chun Yang et al.
Yi-Shan Wang et al.
Introduction: Genome-wide association studies have identified a genetic variant rs17356907 in netrin 4 (NTN4) as a risk locus of breast cancer (BC) in Europeans. NTN4 is a target gene of miR-17-92 cluster that is an oncog...
lncRNA LINC000466 Predicts the Prognosis and Promotes the Progression of Triple-negative Breast Cancer via Modulating miR-539-5p [0.03%]
长链非编码RNA LINC00046通过调控miR-539-5p预测三阴性乳腺癌预后及促进其进展
Jiaqi Liu,Heshan Yu,Haiyun Cui et al.
Jiaqi Liu et al.
Background: Triple-negative breast cancer (TNBC) is one of the most malignant subtypes of breast cancer with an unsatisfied prognosis. Effective biomarkers could predict the risk and improve patients' survival. Whether LI...
Neoadjuvant Chemotherapy for Metaplastic Breast Cancer: Response Rates, Management, and Outcomes [0.03%]
黏液乳腺癌新辅助化疗的疗效、处理和预后
Waqar Haque,Vivek Verma,Mary R Schwartz et al.
Waqar Haque et al.
Introduction: Neoadjuvant chemotherapy (NAC) for breast cance has not been well studied for metaplastic breast cancer (MBC), a rare but aggressive type of breast cancer. ...
Factors Associated With the Decision to Decline Chemotherapy in Patients With Early-stage, ER+/HER2- Breast Cancer and High-risk Scoring on Genomic Assays [0.03%]
基因检测高危评分的早期期雌激素受体阳性/HER2阴性乳腺癌患者放弃化疗决策的影响因素分析
Nadeem Bilani,Shereen El Ladki,Marita Yaghi et al.
Nadeem Bilani et al.
Introduction: The rate of refusal of chemotherapy ranges from 3% to 19%, but varies widely by patient profile and treatment setting. Using a large national registry, we explore factors significantly associated with the de...
The use of neoadjuvant therapy increases the rate of breast conservation in men with locally advanced breast cancer [0.03%]
新辅助治疗可提高男性局部晚期乳腺癌保乳率
Austin D Williams,Robin Ciocca,Jennifer L Sabol et al.
Austin D Williams et al.
Background: Male breast cancer (MBC) is often diagnosed at a later stage and with a more unfavorable tumor-to-breast ratio compared to women, prompting lower rates of breast conservation (BCT). We sought to assess the pra...
Concurrent Chemo-radiation As a Means of Achieving Pathologic Complete Response in Triple Negative Breast Cancer [0.03%]
三阴性乳腺癌病理完全缓解的同期化学放射治疗手段研究
Maryam Nemati Shafaee,Shalini Makawita,Bora Lim et al.
Maryam Nemati Shafaee et al.
Management of triple negative breast cancer (TNBC) that is resistant to chemotherapy remains a challenge. Many studies have investigated the unconventional approach of concurrent chemotherapy with radiation in management of TNBC that is res...
Claudia Martins Galindo,Fernando Augusto de Oliveira Ganzella,Giseli Klassen et al.
Claudia Martins Galindo et al.
The enzyme 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) is a critical engine that supports glucose catabolism. PFKFB3 produces the signaling molecule fructose-2,6-biphosphate (F2,6BP), which activates the second gatekeepe...
Cardiac Function Checkup During Trastuzumab Therapy Among Patients With Breast Cancer [0.03%]
乳腺癌曲妥珠单抗治疗过程中心脏功能检查
Taisuke Ishii,Eriko Nakano,Tomone Watanabe et al.
Taisuke Ishii et al.
Background: Appropriate cardiac function evaluation before trastuzumab therapy is recommended. However, there are no data that show the current practice of appropriate cardiac evaluation for patients receiving postsurgica...