Postmastectomy Radiotherapy With Immediate Implant Reconstruction: Treatment Fractionation, Implant Plane, and Clinical Outcomes [0.03%]
乳房切除术后立即植入物重建的放疗：分割方式、植入平面和临床结局
Sara Falivene,Micaela Motta,Gokoulakrichenane Loganadane et al.
Sara Falivene et al.
Immediate implant-based breast reconstruction (IBR) after mastectomy raises concerns when postmastectomy radiotherapy (PMRT) is required. While conventional PMRT has traditionally used 50 Gy in 25 fractions, hypofractionated schedules are i...
Immune Checkpoint Inhibitors in Elderly Patients With Triple-Negative Breast Cancer: A Systematic Review and Meta-Analysis of Subgroup Evidence [0.03%]
免疫检查点抑制剂在老年三阴性乳腺癌患者中的应用：亚组证据的系统评价和meta分析
Maria Isadora Rodrigues Carlos,Julia Scaramal Mello,Ana Luiza Marçalo de Tolosa et al.
Maria Isadora Rodrigues Carlos et al.
Background: Immune checkpoint inhibitors (ICIs) have advanced the treatment for triple-negative breast cancer (TNBC), but evidence in older adults remains limited. This study assessed the efficacy and safety of ICIs in el...
Severe Adverse Events in Neoadjuvant Therapy of Triple-Negative Breast Cancer: A Systematic Review and Meta-Analysis of Randomized Phase 3 Trials [0.03%]
三阴性乳腺癌新辅助治疗严重不良事件的系统评价和Meta分析
Marcelo Antonini,André Mattar,Marcelo Madeira et al.
Marcelo Antonini et al.
Neoadjuvant therapy (NAT) is standard treatment for triple-negative breast cancer (TNBC) but toxicity is a major concern. This study aimed to assess the incidence and risk of grade ≥ 3 adverse events (AEs) associated with NAT in nonmetasta...
Expectation Versus Reality: Impact of the Choosing Wisely Campaign on Routine Use of Sentinel Lymph Node Biopsy in Women Over 70 With Early-Stage Breast Cancer in an Academic Institution [0.03%]
选择智慧运动对学术机构中70岁以上早期乳腺癌女性常规使用哨点淋巴结活检的影响：期望与现实
Andrea Lifrieri,Simran Malhotra,Allen T Yu et al.
Andrea Lifrieri et al.
Introduction: In 2016, the Society of Surgical Oncology issued a Choosing Wisely recommendation to omit routine sentinel lymph node biopsy (SLNB) in patients ≥ 70 years of age with early stage, low risk, clinically node-...
Impact of Typical Somatic Gene Mutation Characteristics on Homologous Recombination Deficiency in Breast Cancer [0.03%]
乳腺癌中典型体细胞基因突变特征对同源重组修复缺陷的影响
Jinsui Du,Chenglong Duan,Jiaqi Zhang et al.
Jinsui Du et al.
Background: Homologous recombination deficiency (HRD) is an important contributor to genomic instability in breast cancer. This study aimed to characterize the mutational landscape of HRD breast cancer in a Shaanxi cohort...
Clinical and Demographic Characteristics of Patients With Long-Term Disease Control With First-Line Endocrine Therapy Alone for Hormone Receptor Positive, HER2 Negative, Metastatic Breast Cancer [0.03%]
单用一线内分泌治疗长期控制激素受体阳性、HER2阴性转移性乳腺癌患者的临床和人口学特征
Gretchen Kimmick,Asal Pilehvari,Wen You et al.
Gretchen Kimmick et al.
Purpose: To describe characteristics of patients with hormone receptor positive, HER2 negative, metastatic breast cancer (HR + MBC) who have long-term disease control with single-agent, first-line endocrine therapy (ET). ...
The Mediating Role of Serum Phosphate in the BMI-Breast Cancer Association: A Prospective Study from the UK Biobank [0.03%]
英国生物银行队列中BMI与乳腺癌关联中的血磷介导作用：一项前瞻性研究
Wenwen Yang,Yanan Zhang,Min Chen et al.
Wenwen Yang et al.
Background: Globally, breast cancer (BC) represents the most commonly diagnosed malignancy in women. This research explores the relationship between BC risk and both body mass index (BMI) classifications and serum phospha...
Taxane-Induced Peripheral Neuropathy-Driven Treatment Modification and Pathologic Complete Response After Neoadjuvant TCHP in HER2-Positive Breast Cancer: A Retrospective Cohort Study [0.03%]
紫杉烷诱导的外周神经病变驱动的术前TCHP治疗调整和HER2阳性乳腺癌的病理完全缓解：一项回顾性队列研究
Răzvan Adrian Negreanu,Nicolae Verga,Estera Găinariu
Răzvan Adrian Negreanu
Background: Neoadjuvant docetaxel/carboplatin/trastuzumab/pertuzumab (TCHP) is a widely used regimen for human epidermal growth factor receptor 2 (HER2)-positive breast cancer, achieving high rates of pathologic complete ...
Global Burdens and Trends of Breast Cancer Attributable to Dietary and Metabolic Risks: A 30-Year Analysis With Projections to 2050, Including Males and Females [0.03%]
1990-2019年全球乳腺癌归因于饮食和代谢风险的疾病负担及趋势：包括男性和女性，以及2050年预测
Ranze Zhang,Xingpeng Qiu,Xiangzhan Kong et al.
Ranze Zhang et al.
Objectives: Modifiable dietary and metabolic factors are leading risk factors for breast cancer (BC). This study comprehensively analyzed their attributable burdens and trends across global, regional, sex, and age dimensi...
A Decade of Human Epidermal Growth Factor Receptor 2 (HER2) Testing in Breast Cancer in Spain: A Comprehensive Real-World Data Analysis (2013-2023) [0.03%]
西班牙乳腺癌人表皮生长因子受体2（HER2）检测十年回顾：2013-2023真实世界数据分析综合分析
Vicente Peg,Octavio Burgués,Irune Ruiz et al.
Vicente Peg et al.
Background: Evaluating human epidermal growth factor receptor 2 (HER2) expression is essential for guiding targeted therapies in breast cancer (BC). In Spain, the CONFIRMA-HER2 registry is the main source of information o...