Habitat-Based MRI Radiomics for Predicting Breast-Conserving Surgery Feasibility After Neoadjuvant Chemotherapy in Breast Cancer: A Multicenter Study [0.03%]
基于乳腺癌新辅助化疗后保乳手术可行性的影像组学研究：多中心研究报告
Jinrui Liu,Mingsong Tang,Fei Jia et al.
Jinrui Liu et al.
Background: Neoadjuvant chemotherapy (NAC) is widely used in the management of breast cancer, as it can downstage tumors and increase the rate of breast-conserving surgery (BCS). Accurate preoperative prediction of BCS el...
Minimal Clinically Important Differences to Determine Meaningful Change in the Skin Symptom Assessment (SSA) Questionnaire for the Randomized Controlled Trial of Mepitel Film Versus Standard of Care for the Prevention of Acute and Chronic Dermatitis in Breast Cancer Radiation Treatment [0.03%]
评估皮肤症状评分量表的最小临床重要差异以确定乳腺癌放射治疗中生物膜敷料预防急性及慢性皮炎的随机对照研究中变化的意义
Christina Yang,Laura Tang,Liying Zhang et al.
Christina Yang et al.
Background: Changes in patient-reported outcomes may be statistically significant, but not necessarily clinically significant. This study determined the minimal clinically important differences (MCIDs) in the Skin Symptom...
Tucatinib in Combination With Trastuzumab Deruxtecan in Patients With Previously Treated HER2+ Unresectable Locally Advanced or Metastatic Breast Cancer: An Open-Label Phase 2 Study [0.03%]
Tucatinib联合Trastuzumab Deruxtecan治疗HER2阳性不可切除局部晚期或转移性乳腺癌患者的开放性II期临床研究
Shanu Modi,Rashmi K Murthy,A Jo Chien et al.
Shanu Modi et al.
Introduction: Recent advances in HER2-directed therapies have improved outcomes for patients with HER2+ advanced/metastatic breast cancer (a/mBC), but disease progression ultimately occurs in most cases. Dual targeting of...
Refining Stratification in Premenopausal Node-Positive HR+/HER2- Breast Cancer With a Novel AI-Based Test [0.03%]
新型AI检测在绝经前淋巴结阳性HR+/HER2-乳腺癌中的分层优化研究
Jailan Elayoubi,Cerise Tang,Kathryn J Ruddy et al.
Jailan Elayoubi et al.
Background: Genomic assays are considered the standard of care for stratification and chemotherapy benefit prediction in postmenopausal women with breast cancer. However, clinical trials indicate that these tools have lim...
A Cohort Study of the Effectiveness of Trastuzumab Deruxtecan for Treating Metastatic Progressive HER2-Positive Breast Cancer [0.03%]
一项关于tramstuzumab deruxtecan治疗转移性HER2阳性乳腺癌疗效的队列研究
Ameer Basta,Kyle Lien,Gabris Ni et al.
Ameer Basta et al.
Introduction: The FDA approved trastuzumab deruxtecan (T-DXd) for treating human epidermal growth factor receptor 2-positive (HER2+) metastatic breast cancer (mBC) based on the phase II trial DESTINY-Breast01. The phase I...
COVID-19 as a Catalyst for Ultra-Hypofractionated Radiotherapy in Early Breast Cancer: Trends, Predictors, and Estimated Cost Savings [0.03%]
新冠肺炎疫情下早期乳腺癌超低分割放疗的现状、预测因素及成本节约估算
Riley McDougall,Yangyang Shi,Jared Robbins et al.
Riley McDougall et al.
Background: COVID-19 significantly impacted radiation treatment trends in early breast cancer. An ASCO survey showed a 40% shift worldwide toward ultra-hypofractionated (UHF) or radiation omission in eligible patients. Th...
LINC01234 Coordinates Protein Interactions and ceRNA Networks to Enhance YWHAZ-Driven Malignancy in Triple-Negative Breast Cancer [0.03%]
LINC01234通过协调蛋白质相互作用和ceRNA网络增强YWHAZ驱动的三阴性乳腺癌恶性进展
Diping Yu,Li Chen,Huimin Li et al.
Diping Yu et al.
Background: Triple-negative breast cancer (TNBC) lacks effective therapies. Long noncoding RNA LINC01234 is upregulated in TNBC and promotes progression, but its molecular mechanism requires elucidation. ...
The Clinical Impact of Not Performing Axillary Lymph Node Dissection in pN+sn Breast Cancer Patients Undergoing Total Mastectomy [0.03%]
pN+乳腺癌患者行乳房切除术后未行腋窝淋巴结廓清的临床影响
Beatriz Maganinho,Bárbara Peleteiro,Ricardo Pereira et al.
Beatriz Maganinho et al.
Background: The sentinel lymph node (SLN) concept has changed the paradigm of surgical staging of breast cancer (BC) patients, allowing fewer patients to undergo axillary lymph node dissection (ALND) when the SLN is metas...
Reducing Clip Migration in Mammographic-Guided Vacuum Assisted Biopsy With Direct Insertion of the UltraCor Twirl Clip Marker: A Quality Improvement Project [0.03%]
改良Vacuum Breast Biopsy定位标记物的放置方法以降低标记物移位的概率：质量改进项目报告
Sabrina Omar Bintalib,Shiu Suwn Yeo,Hin Yeung Marcus Loh et al.
Sabrina Omar Bintalib et al.
Background: Clip migration is frequently observed in mammographic-guided vacuum-assisted biopsies (VAB) and is associated with greater tissue excision and re-excision rates. Our institutional baseline clip migration rate ...
Tracking Utilization of Neoadjuvant Endocrine Therapy (NET) and Neoadjuvant Chemotherapy (NCT) for Hormone Receptor-Positive Breast Cancer (HR + BC) in the U.S.A. Over Time - A TriNetX Database Study [0.03%]
美国三联数据库研究：随访一段时间内激素受体阳性乳腺癌患者对新辅助内分泌治疗（NET）和新辅助化疗（NCT）的利用情况
Jubin K Lim,Anna E Gibson,Jian He et al.
Jubin K Lim et al.
Purpose: Hormone receptor-positive breast cancer (HR + BC) responds well to neoadjuvant endocrine therapy (NET), increasing chances for breast conserving surgery with less toxicity than neoadjuvant chemotherapy (NCT). A N...