Adilia Warris,Thomas Lehrnbecher
Adilia Warris
Purpose of review: This review summarizes the fungal diagnostic measures currently available for use in paediatric patients at high risk for developing invasive fungal disease (IFD) and those suspected of having an IFD. T...
Craig Williams,Ranjith Ranjendran,Gordon Ramage
Craig Williams
For a long time, the microbiology of cystic fibrosis has been focussed on Pseudomonas aeruginosa and associated Gram-negative pathogens. An increasing body of evidence has been compiled demonstrating an important role for moulds and yeasts ...
Bart G J Dekkers,Martijn Bakker,Kim C M van der Elst et al.
Bart G J Dekkers et al.
Posaconazole is a second-generation triazole agent with a potent and broad antifungal activity. In addition to the oral suspension, a delayed-release tablet and intravenous formulation with improved pharmacokinetic properties have been intr...
Point of Care Testing for the Diagnosis of Fungal Infections: Are We There Yet? [0.03%]
现场检测在真菌感染诊断中的应用：我们现在达到目标了吗？
Juergen Prattes,Sven Heldt,Susanne Eigl et al.
Juergen Prattes et al.
Diagnostic tools for invasive fungal infections have continuously improved within the last decades. Nowadays, cultural methods, antigen testing, and molecular tests, such as polymerase chain reaction, are widely used. These methods, however...
Jan Zoll,Eveline Snelders,Paul E Verweij et al.
Jan Zoll et al.
New state-of-the-art techniques in sequencing offer valuable tools in both detection of mycobiota and in understanding of the molecular mechanisms of resistance against antifungal compounds and virulence. Introduction of new sequencing plat...
Elizabeth Nalintya,Reuben Kiggundu,David Meya
Elizabeth Nalintya
Over the last decade, an upsurge in both the frequency and severity of fungal infections due to the HIV/AIDS epidemic and the use of immunosuppressive therapy has occurred. Even diagnostic methods like culture and microscopy, which have low...
The European Paediatric Mycology Network (EPMyN): Towards a Better Understanding and Management of Fungal Infections in Children [0.03%]
欧洲儿童真菌学会（EPMyN）：提高对儿童真菌感染的认识和管理能力以应对儿童真菌感染挑战
Adilia Warris;European Paediatric Mycology Network (EPMyN)*
Adilia Warris;European Paediatric Mycology Network (EPMyN)*
The European Paediatric Mycology Network (EPMyN) was launched in 2014 to create a European platform for research and education in the field of paediatric mycology. The EPMyN aims to address the lack of paediatric specific evidence and knowl...
Therapeutic Drug Monitoring and Genotypic Screening in the Clinical Use of Voriconazole [0.03%]
伏立康唑临床应用中的治疗药物监测及基因型筛查
Brad Moriyama,Sameer Kadri,Stacey A Henning et al.
Brad Moriyama et al.
Voriconazole is an antifungal triazole that is the first line agent for treatment of invasive aspergillosis. It is metabolized by CYP2C19, CYP2C9, and CYP3A4 and demonstrates wide interpatient variability in serum concentrations. Polymorphi...
Neonatal Candidiasis: New Insights into an Old Problem at a Unique Host-Pathogen Interface [0.03%]
新生儿念珠菌病：一个独特宿主-病原体界面的老问题新见解
Amanda B Arsenault,Joseph M Bliss
Amanda B Arsenault
Candida species are the leading cause of invasive fungal infections in premature infants. Associated with substantial morbidity and mortality, these infections represent serious and sometimes catastrophic complications in the course of hosp...
Recent Taxonomic Developments with Candida and Other Opportunistic Yeasts [0.03%]
近年来机会致病酵母菌（主要是毕赤氏酵母）的分类学进展
Mary E Brandt,Shawn R Lockhart
Mary E Brandt
Increases in susceptible patient populations and advances in identification methods have resulted in the continued recognition of novel yeasts as agents of human infection. Most of these agents are members of the well-recognized genera Cand...