Ryan E Leighton,Ariel M Alperstein,Renee R Frontiera
Ryan E Leighton
Biological and material samples contain nanoscale heterogeneities that are unresolvable with conventional microscopy techniques. Super-resolution fluorescence methods can break the optical diffraction limit to observe these features, but th...
Angelika B Harbauer,Annika Schneider,Dirk Wohlleber
Angelika B Harbauer
Cellular organelles are highly specialized compartments with distinct functions. With the increasing resolution of detection methods, it is becoming clearer that same organelles may have different functions or properties not only within dif...
Kenneth Marshall Seaton,Morgan Leigh Cable,Amanda Michelle Stockton
Kenneth Marshall Seaton
One of the greatest and most long-lived scientific pursuits of humankind has been to discover and study the planetary objects comprising our solar system. Information gained from solar system observations, via both remote sensing and in sit...
W Russ Algar,Katherine D Krause
W Russ Algar
Förster resonance energy transfer (FRET) is a widely used fluorescence-based sensing mechanism. To date, most implementations of FRET sensors have relied on a discrete donor-acceptor pair for detection of each analytical target. FRET netwo...
Quantitative Stimulated Raman Scattering Microscopy: Promises and Pitfalls [0.03%]
定量刺激拉曼散射显微镜：希望与挑战
Bryce Manifold,Dan Fu
Bryce Manifold
Since its first demonstration, stimulated Raman scattering (SRS) microscopy has become a powerful chemical imaging tool that shows promise in numerous biological and biomedical applications. The spectroscopic capability of SRS enables ident...
Giada Caniglia,Gözde Tezcan,Gabriel N Meloni et al.
Giada Caniglia et al.
Surface charge density and distribution play an important role in almost all interfacial processes, influencing, for example, adsorption, colloidal stability, functional material activity, electrochemical processes, corrosion, nanoparticle ...
Overcoming Major Barriers to Developing Successful Sensors for Practical Applications Using Functional Nucleic Acids [0.03%]
利用功能性核酶和核酸克服传感器开发中的主要障碍以用于实际应用中
JingJing Zhang,Tian Lan,Yi Lu
JingJing Zhang
For many years, numerous efforts have been focused on the development of sensitive, selective, and practical sensors for environmental monitoring, food safety, and medical diagnostic applications. However, the transition from innovative res...
David S Kinnamon,Jacob T Heggestad,Jason Liu et al.
David S Kinnamon et al.
Immunoassays are a powerful tool for sensitive and quantitative analysis of a wide range of biomolecular analytes in the clinic and in research laboratories. However, enzyme-linked immunosorbent assay (ELISA)-the gold-standard assay-require...
Jean-François Lemineur,Hui Wang,Wei Wang et al.
Jean-François Lemineur et al.
An optical microscope is probably the most intuitive, simple, and commonly used instrument to observe objects and discuss behaviors through images. Although the idea of imaging electrochemical processes operando by optical microscopy was in...
Surface Analysis Techniques in Forensic Science: Successes, Challenges, and Opportunities for Operational Deployment [0.03%]
表面分析技术在法医科学中的应用：成功、挑战及实战部署的机会
Melanie J Bailey,Marcel de Puit,Francesco Saverio Romolo
Melanie J Bailey
Surface analysis techniques have rapidly evolved in the last decade. Some of these are already routinely used in forensics, such as for the detection of gunshot residue or for glass analysis. Some surface analysis approaches are attractive ...