Eric S McLamore,Shoumen P A Datta
Eric S McLamore
The goal of protecting the health of future generations is a blueprint for future biosensor design. Systems-level decision support requires that biosensors provide meaningful service to society. In this review, we summarize recent developme...
Enhancing the Depth of Analyses with Next-Generation Ion Mobility Experiments [0.03%]
采用下一代离子淌度实验增强分析深度
Benjamin P Zercher,Theresa A Gozzo,AnneClaire Wageman et al.
Benjamin P Zercher et al.
Recent developments in ion mobility (IM) technology have expanded the capability to separate and characterize gas-phase ions of biomolecules, especially when paired with mass spectrometry. This next generation of IM technology has been ushe...
Advances and Emerging Medical Applications of Direct Mass Spectrometry Technologies for Tissue Analysis [0.03%]
直接质量分析技术在组织分析中的进展和新兴医学应用
Mary E King,Monica Lin,Meredith Spradlin et al.
Mary E King et al.
Offering superb speed, chemical specificity, and analytical sensitivity, direct mass spectrometry (MS) technologies are highly amenable for the molecular analysis of complex tissues to aid in disease characterization and help identify new d...
Pei-Heng Lin,Hsin-Hua Nien,Bor-Ran Li
Pei-Heng Lin
The development of wearable devices provides approaches for the realization of self-health care. Easily carried wearable devices allow individual health monitoring at any place whenever necessary. There are various interesting monitoring ta...
Kira L Rahn,Umesha Peramune,Tianyi Zhang et al.
Kira L Rahn et al.
Label-free electrochemical biosensing leverages the advantages of label-free techniques, low cost, and fewer user steps, with the sensitivity and portability of electrochemical analysis. In this review, we identify four label-free electroch...
Nondestructive 3D Pathology with Light-Sheet Fluorescence Microscopy for Translational Research and Clinical Assays [0.03%]
用于转化研究和临床检验的非破坏性三维病理光片荧光显微镜技术
Jonathan T C Liu,Adam K Glaser,Chetan Poudel et al.
Jonathan T C Liu et al.
In recent years, there has been a revived appreciation for the importance of spatial context and morphological phenotypes for both understanding disease progression and guiding treatment decisions. Compared with conventional 2D histopatholo...
Bailey L Bowser,Renã A S Robinson
Bailey L Bowser
The identification of thousands of proteins and their relative levels of expression has furthered understanding of biological processes and disease and stimulated new systems biology hypotheses. Quantitative proteomics workflows that rely o...
Saliva Diagnostics [0.03%]
saliva诊断学
Taichiro Nonaka,David T W Wong
Taichiro Nonaka
Cancer remains one of the leading causes of death, and early detection of this disease is crucial for increasing survival rates. Although cancer can be diagnosed following tissue biopsy, the biopsy procedure is invasive; liquid biopsy provi...
Samantha M Grist,Kevin L Bennewith,Karen C Cheung
Samantha M Grist
Oxygen plays a fundamental role in respiration and metabolism, and quantifying oxygen levels is essential in many environmental, industrial, and research settings. Microdevices facilitate the study of dynamic, oxygen-dependent effects in re...
Mass Spectrometry Measurements of Neuropeptides: From Identification to Quantitation [0.03%]
神经肽的质谱测定：从鉴定到定量
Eduardo A De La Toba,Sara E Bell,Elena V Romanova et al.
Eduardo A De La Toba et al.
Neuropeptides (NPs), a unique class of neuronal signaling molecules, participate in a variety of physiological processes and diseases. Quantitative measurements of NPs provide valuable information regarding how these molecules are different...