Toward Unrivaled Chromatographic Resolving Power in Proteomics: Design and Development of Comprehensive Spatial Three-Dimensional Liquid-Phase Separation Technology [0.03%]
迈向蛋白质组学中无与伦比的色谱分辨率：综合性空间三维液相分离技术的设计与开发
Sebastiaan Eeltink,Jelle De Vos,Gert Desmet
Sebastiaan Eeltink
Spatial comprehensive three-dimensional chromatography (3D-LC) offers an innovative approach to achieve unprecedented resolving power in terms of peak capacity and sample throughput. This advanced technique separates components within a 3D ...
Label-Free Optical Technologies to Enhance Noninvasive Endoscopic Imaging of Early-Stage Cancers [0.03%]
无标签光学技术提高非侵入性内窥镜成像早期癌症的能力
Shuang Chang,Halina Krzyzanowska,Audrey K Bowden
Shuang Chang
White light endoscopic imaging allows for the examination of internal human organs and is essential in the detection and treatment of early-stage cancers. To facilitate diagnosis of precancerous changes and early-stage cancers, label-free o...
Maximizing Analytical Performance in Biomolecular Discovery with LC-MS: Focus on Psychiatric Disorders [0.03%]
液质联用(LC-MS)在生物分子发现中对精神障碍的分析性能最大化
Bradley J Smith,Paul C Guest,Daniel Martins-de-Souza
Bradley J Smith
In this review, we discuss the cutting-edge developments in mass spectrometry proteomics and metabolomics that have brought improvements for the identification of new disease-based biomarkers. A special focus is placed on psychiatric disord...
Emerging Areas in Undergraduate Analytical Chemistry Education: Microfluidics, Microcontrollers, and Chemometrics [0.03%]
本科分析化学教育中的新兴领域：微流控、微控制器和化学计量学
Amber M Hupp,Michelle L Kovarik,Daniel A McCurry
Amber M Hupp
Analytical chemistry is a fast-paced field with frequent introduction of new techniques via research labs; however, incorporation of new techniques into academic curricula lags their adoption in research and industry. This review describes ...
Raman and Surface-Enhanced Raman Scattering Detection in Flowing Solutions for Complex Mixture Analysis [0.03%]
流动溶液中的拉曼和表面增强拉曼散射检测在复杂混合物分析中的应用
Monika Poonia,Courtney J Morder,Hannah C Schorr et al.
Monika Poonia et al.
Raman scattering provides a chemical-specific and label-free method for identifying and quantifying molecules in flowing solutions. This review provides a comprehensive examination of the application of Raman spectroscopy and surface-enhanc...
Justin C Rolando,Arek V Melkonian,David R Walt
Justin C Rolando
Nucleic acid testing is the cornerstone of modern molecular diagnostics. This review describes the current status and future directions of molecular diagnostics, focusing on four major techniques: polymerase chain reaction (PCR), next-gener...
Blanca H Lapizco-Encinas
Blanca H Lapizco-Encinas
Nonlinear electrokinetic phenomena offer label-free, portable, and robust approaches for particle and cell assessment, including selective enrichment, separation, sorting, and characterization. The field of electrokinetics has evolved subst...
Lisa A Holland,Laura D Casto-Boggess
Lisa A Holland
Gel matrices are fundamental to electrophoresis analyses of biopolymers in microscale channels. Both capillary gel and microchannel gel electrophoresis systems have produced fundamental advances in the scientific community. These analytical...
Trung Duc Nguyen,Yuan-I Chen,Limin H Chen et al.
Trung Duc Nguyen et al.
Since the early 1990s, single-molecule detection in solution at room temperature has enabled direct observation of single biomolecules at work in real time and under physiological conditions, providing insights into complex biological syste...
Emerging Chemical Methods for Petroleum and Petroleum-Derived Dissolved Organic Matter Following the Deepwater Horizon Oil Spill [0.03%]
深水地平线漏油事件后石油及石油衍生的溶解有机质化学分析法的发展研究进展
Phoebe Zito,David C Podgorski,Matthew A Tarr
Phoebe Zito
Despite the fact that oil chemistry and oils spills have been studied for many years, there are still emerging techniques and unknown processes to be explored. The 2010 Deepwater Horizon oil spill in the Gulf of Mexico resulted in a revival...