Soft X-Ray Tomography Has Evolved into a Powerful Tool for Revealing Cell Structures [0.03%]
软X射线层析成像技术已进化成为揭示细胞结构的强有力工具
Venera Weinhardt,Carolyn Larabell
Venera Weinhardt
Over the past three decades, soft X-ray tomography (SXT) rapidly evolved from a proof-of-concept microscopy method into a high-throughput quantitative imaging modality. This advancement enables researchers to address central questions in ce...
Advances in Online Comprehensive Two-Dimensional Liquid Chromatography Method Development [0.03%]
在线综合二维液相色谱方法的发展进展
Eugene H J Nell,Magriet Muller,André de Villiers
Eugene H J Nell
Comprehensive two-dimensional liquid chromatography (LC×LC) is increasingly being used to provide new information on the composition of complex samples. More widespread use of the technique is, however, hampered by the complexity of method...
Forensic Analytical Chemistry for Minimizing Injustice: Advances and Challenges [0.03%]
法医分析化学在减少不公正现象中的应用：进展与挑战
Raychelle Burks,Georgina Sauzier,Brooke W Kammrath et al.
Raychelle Burks et al.
Forensic analytical chemistry has evolved significantly, embracing a myriad of methodological and technological advancements to expand the frontiers of evidence analysis. Beyond technology, modern forensic scientists face challenges working...
Yuhui Hong,Yuzhen Ye,Haixu Tang
Yuhui Hong
Tandem mass spectrometry (MS/MS) is crucial for small-molecule analysis; however, traditional computational methods are limited by incomplete reference libraries and complex data processing. Machine learning (ML) is transforming small-molec...
Dagwin Wachholz Junior,Patricia Batista Deroco,Bruna M Hryniewicz et al.
Dagwin Wachholz Junior et al.
Electrochemical biosensors have emerged as pivotal tools in point-of-care (POC) sensing, offering rapid, sensitive, and cost-effective detection platforms. Different strategies for advancing electrochemical POC biosensors have been explored...
Eleonora Macchia,Paolo Bollella,Luisa Torsi
Eleonora Macchia
Bioelectronics, originating from Galvani's eighteenth-century experiments, blends biology, medicine, and electronics to create devices that can be closely connected to biological systems. This review focuses on bioelectronic large-area fiel...
Microfluidics with Machine Learning for Biophysical Characterization of Cells [0.03%]
利用微流体和机器学习进行细胞的生物物理特性分析
Hyungkook Jeon,Jongyoon Han
Hyungkook Jeon
Understanding the biophysical properties of cells is essential for biological research, diagnostics, and therapeutics. Microfluidics enhances biophysical cell characterization by enabling precise manipulation and real-time measurement at th...
Guanwei Zhou,Wenjing Wang
Guanwei Zhou
Protein engineering has been extensively applied to the development of genetically encoded reporters for spatiotemporally resolved monitoring of dynamic biochemical activity across cellular compartments in living cells. Genetically encoded ...
Analytic Approaches to Physicochemical Properties of Materials for Biomedical Applications Across Nanoscopic and Macroscopic Length Scales [0.03%]
用于生物医学应用的材料在纳米和宏观尺度上的物理化学性质的解析方法
Farnaz Fazelpour,Lindsey C Hill,Matthew R Markovetz et al.
Farnaz Fazelpour et al.
The design and implementation of biomedical devices for both diagnostic and direct medical applications have revolutionized patient care, paving the way for improved patient outcomes. Understanding the characteristics of materials used in t...
Environmental Exposures and Health Risks: A Metabolomics Perspective on Exposomics Research [0.03%]
环境暴露与健康风险： exposomics研究的代谢组学视角
Ana Ruxandra Stanciu,Claire Gillespie,Philip Britz-McKibbin
Ana Ruxandra Stanciu
Exposomics refers to the comprehensive analysis of environmental exposures over the lifespan and assessment of their biological effects on human health. This new frontier in environmental research promises new insights for assessment of the...