Zuo-Fei Yuan,Anna M Arnaudo,Benjamin A Garcia
Zuo-Fei Yuan
Histones play important roles in chromatin, in the forms of various posttranslational modifications (PTMs) and sequence variants, which are called histone proteoforms. Investigating modifications and variants is an ongoing challenge. Previo...
Long Luo,Sean R German,Wen-Jie Lan et al.
Long Luo et al.
The development of nanopore fabrication methods during the past decade has led to the resurgence of resistive-pulse analysis of nanoparticles. The newly developed resistive-pulse methods enable researchers to simultaneously study properties...
Xiangling Xiong,Yifan Lv,Tao Chen et al.
Xiangling Xiong et al.
Cells as the building blocks of life determine the basic functions and properties of a living organism. Understanding the structure and components of a cell aids in the elucidation of its biological functions. Moreover, knowledge of the sim...
Microfluidics-based single-cell functional proteomics for fundamental and applied biomedical applications [0.03%]
基于微流控的单细胞功能蛋白质组学在基础和应用生物医学中的作用
Jing Yu,Jing Zhou,Alex Sutherland et al.
Jing Yu et al.
We review an emerging microfluidics-based toolkit for single-cell functional proteomics. Functional proteins include, but are not limited to, the secreted signaling proteins that can reflect the biological behaviors of immune cells or the i...
A life in electrochemistry [0.03%]
电化学人生
Allen J Bard
Allen J Bard
Zdenek Slouka,Satyajyoti Senapati,Hsueh-Chia Chang
Zdenek Slouka
When integrated into microfluidic chips, ion-selective nanoporous polymer and solid-state membranes can be used for on-chip pumping, pH actuation, analyte concentration, molecular separation, reactive mixing, and molecular sensing. They off...
Muhammad Safwan Akram,Jawad Ur Rehman,Elizabeth A H Hall
Muhammad Safwan Akram
It is only in the past two decades that excellent protein engineering tools have begun to meet parallel advances in materials chemistry, nanofabrication, and electronics. This is revealing scenarios from which synthetic enzymes can emerge, ...
Optical imaging of individual plasmonic nanoparticles in biological samples [0.03%]
生物样品中单个等离激元纳米颗粒的光学成像研究
Lehui Xiao,Edward S Yeung
Lehui Xiao
Imaging of plasmonic nanoparticles (PNP) with optical microscopy has aroused considerable attention in recent years. The unique localized surface plasmon resonance (LSPR) from metal nanoparticles facilitates the transduction of a chemical o...
Mirek Macka,Tomasz Piasecki,Purnendu K Dasgupta
Mirek Macka
Light-emitting diodes (LEDs) are playing increasingly important roles in analytical chemistry, from the final analysis stage to photoreactors for analyte conversion to actual fabrication of and incorporation in microdevices for analytical u...
Karen Dawson,Alan O&#x;Riordan
Karen Dawson
This article reviews the state of the art of silicon chip-based nanoelectrochemical devices for sensing applications. We first describe analyte mass transport to nanoscale electrodes and emphasize understanding the importance of mass transp...