Biologically inspired nanofibers for use in translational bioanalytical systems [0.03%]
仿生纳米纤维在转化生物分析系统中的应用研究
Lauren Matlock-Colangelo,Antje J Baeumner
Lauren Matlock-Colangelo
Electrospun nanofiber mats are characterized by large surface-area-to-volume ratios, high porosities, and a diverse range of chemical functionalities. Although electrospun nanofibers have been used successfully to increase the immobilizatio...
Erica M Forsberg,Clémence Sicard,John D Brennan
Erica M Forsberg
In the past 30 years, there has been a significant growth in the use of solid-phase assays in the area of drug discovery, with a range of new assays being used for both soluble and membrane-bound targets. In this review, we provide some bas...
Klaus Mathwig,Thijs J Aartsma,Gerard W Canters et al.
Klaus Mathwig et al.
The development of experiments capable of probing individual molecules has led to major breakthroughs in fields ranging from molecular electronics to biophysics, allowing direct tests of knowledge derived from macroscopic measurements and e...
M Ariel Geer,Michael C Fitzgerald
M Ariel Geer
Over the past 15 years, a series of energetics-based techniques have been developed for the thermodynamic analysis of protein folding and stability. These techniques include Stability of Unpurified Proteins from Rates of amide H/D Exchange ...
Il-Hoon Cho,Adarsh D Radadia,Khashayar Farrokhzad et al.
Il-Hoon Cho et al.
Despite continuing research efforts, timely and simple pathogen detection with a high degree of sensitivity and specificity remains an elusive goal. Given the recent explosion of sensor technologies, significant strides have been made in ad...
Zuo-Fei Yuan,Anna M Arnaudo,Benjamin A Garcia
Zuo-Fei Yuan
Histones play important roles in chromatin, in the forms of various posttranslational modifications (PTMs) and sequence variants, which are called histone proteoforms. Investigating modifications and variants is an ongoing challenge. Previo...
Long Luo,Sean R German,Wen-Jie Lan et al.
Long Luo et al.
The development of nanopore fabrication methods during the past decade has led to the resurgence of resistive-pulse analysis of nanoparticles. The newly developed resistive-pulse methods enable researchers to simultaneously study properties...
Xiangling Xiong,Yifan Lv,Tao Chen et al.
Xiangling Xiong et al.
Cells as the building blocks of life determine the basic functions and properties of a living organism. Understanding the structure and components of a cell aids in the elucidation of its biological functions. Moreover, knowledge of the sim...
Microfluidics-based single-cell functional proteomics for fundamental and applied biomedical applications [0.03%]
基于微流控的单细胞功能蛋白质组学在基础和应用生物医学中的作用
Jing Yu,Jing Zhou,Alex Sutherland et al.
Jing Yu et al.
We review an emerging microfluidics-based toolkit for single-cell functional proteomics. Functional proteins include, but are not limited to, the secreted signaling proteins that can reflect the biological behaviors of immune cells or the i...
A life in electrochemistry [0.03%]
电化学人生
Allen J Bard
Allen J Bard