Matthew R Lockett,Lloyd M Smith
Matthew R Lockett
Since their advent in the early 1990s, microarray technologies have developed into a powerful and ubiquitous platform for biomolecular analysis. Microarrays consist of three major elements: the substrate upon which they are constructed, the...
Iontronics [0.03%]
离子学器件
Honggu Chun,Taek Dong Chung
Honggu Chun
Iontronics is an emerging technology based on sophisticated control of ions as signal carriers that bridges solid-state electronics and biological system. It is found in nature, e.g., information transduction and processing of brain in whic...
Functionalizing Microporous Membranes for Protein Purification and Protein Digestion [0.03%]
用于蛋白质纯化和蛋白质水解的功能性微孔膜
Jinlan Dong,Merlin L Bruening
Jinlan Dong
This review examines advances in the functionalization of microporous membranes for protein purification and the development of protease-containing membranes for controlled protein digestion prior to mass spectrometry analysis. Recent studi...
Andrea Centrone
Andrea Centrone
Progress in nanotechnology is enabled by and dependent on the availability of measurement methods with spatial resolution commensurate with nanomaterials' length scales. Chemical imaging techniques, such as scattering scanning near-field op...
Eric A Hunt,David Broyles,Trajen Head et al.
Eric A Hunt et al.
The relatively new field of microRNA (miR) has experienced rapid growth in methodology associated with its detection and bioanalysis as well as with its role in -omics research, clinical diagnostics, and new therapeutic strategies. The brea...
Elizabeth S Bucher,R Mark Wightman
Elizabeth S Bucher
Chemical signaling through the release of neurotransmitters into the extracellular space is the primary means of communication between neurons. More than four decades ago, Ralph Adams and his colleagues realized the utility of electrochemic...
Concerted proton-electron transfers: fundamentals and recent developments [0.03%]
协同质子-电子转移：基础与最新研究进展
Jean-Michel Savéant
Jean-Michel Savéant
Proton-coupled electron transfers (PCET) are ubiquitous in natural and synthetic processes. This review focuses on reactions where the two events are concerted. Semiclassical models of such reactions allow their kinetic characterization thr...
Günter Mistlberger,Gastón A Crespo,Eric Bakker
Günter Mistlberger
This review provides an overview of the key aspects of designing ionophore-based optical sensors (IBOS). Exact response functions are developed and compared with a simplified, generalized equation. We also provide a brief introduction into ...
Anton Amann,Wolfram Miekisch,Jochen Schubert et al.
Anton Amann et al.
Breath analysis is a young field of research with great clinical potential. As a result of this interest, researchers have developed new analytical techniques that permit real-time analysis of exhaled breath with breath-to-breath resolution...
Zhaorui Zhang,Si Wu,David L Stenoien et al.
Zhaorui Zhang et al.
Mass spectrometry (MS)-based high-throughput proteomics is the core technique for large-scale protein characterization. Due to the extreme complexity of proteomes, sophisticated separation techniques and advanced MS instrumentation have bee...