Elizabeth S Bucher,R Mark Wightman
Elizabeth S Bucher
Chemical signaling through the release of neurotransmitters into the extracellular space is the primary means of communication between neurons. More than four decades ago, Ralph Adams and his colleagues realized the utility of electrochemic...
Concerted proton-electron transfers: fundamentals and recent developments [0.03%]
协同质子-电子转移：基础与最新研究进展
Jean-Michel Savéant
Jean-Michel Savéant
Proton-coupled electron transfers (PCET) are ubiquitous in natural and synthetic processes. This review focuses on reactions where the two events are concerted. Semiclassical models of such reactions allow their kinetic characterization thr...
Günter Mistlberger,Gastón A Crespo,Eric Bakker
Günter Mistlberger
This review provides an overview of the key aspects of designing ionophore-based optical sensors (IBOS). Exact response functions are developed and compared with a simplified, generalized equation. We also provide a brief introduction into ...
Anton Amann,Wolfram Miekisch,Jochen Schubert et al.
Anton Amann et al.
Breath analysis is a young field of research with great clinical potential. As a result of this interest, researchers have developed new analytical techniques that permit real-time analysis of exhaled breath with breath-to-breath resolution...
Zhaorui Zhang,Si Wu,David L Stenoien et al.
Zhaorui Zhang et al.
Mass spectrometry (MS)-based high-throughput proteomics is the core technique for large-scale protein characterization. Due to the extreme complexity of proteomes, sophisticated separation techniques and advanced MS instrumentation have bee...
Resonance-enhanced multiphoton ionization mass spectrometry (REMPI-MS): applications for process analysis [0.03%]
共振增强多光子电离质谱(REMPI-MS)在过程分析中的应用
Thorsten Streibel,Ralf Zimmermann
Thorsten Streibel
Process analysis is an emerging discipline in analytical sciences that poses special requirements on analytical techniques, especially when conducted in an online manner. Mass spectrometric methods seem exceedingly suitable for this task, p...
Point-of-care platforms [0.03%]
现场检测平台技术
Günter Gauglitz
Günter Gauglitz
Point-of-care applications are gaining increasing interest in clinical diagnostics and emergency applications. Biosensors are used to monitor the biomolecular interaction process between a disease biomarker and a recognition element such as...
Ambient femtosecond laser vaporization and nanosecond laser desorption electrospray ionization mass spectrometry [0.03%]
飞秒激光蒸发和纳秒激光解吸电喷雾质谱法
Paul Flanigan,Robert Levis
Paul Flanigan
Recent investigations of ambient laser-based transfer of molecules into the gas phase for subsequent mass spectral analysis have undergone a renaissance resulting from the separation of vaporization and ionization events. Here, we seek to p...
Patrick Giraudeau,Lucio Frydman
Patrick Giraudeau
Two-dimensional nuclear magnetic resonance (2D NMR) spectroscopy is widely used in chemical and biochemical analyses. Multidimensional NMR is also witnessing increased use in quantitative and metabolic screening applications. Conventional 2...
Analytical approaches for size and mass analysis of large protein assemblies [0.03%]
大型蛋白质复合物尺寸和质量分析的分析方法
Joost Snijder,Albert J R Heck
Joost Snijder
Analysis of the size and mass of nanoparticles, whether they are natural biomacromolecular or synthetic supramolecular assemblies, is an important step in the characterization of such molecular species. In recent years, electrospray ionizat...