Kevin J Johnson,Susan L Rose-Pehrsson
Kevin J Johnson
Chemical detection in complex environments presents numerous challenges for successful implementation. Arrays of sensors are often implemented for complex chemical sensing tasks, but systematic understanding of how individual sensor respons...
I-Chung Lu,Chuping Lee,Yuan-Tseh Lee et al.
I-Chung Lu et al.
In past studies, mistakes in determining the ionization mechanism in matrix-assisted laser desorption/ionization (MALDI) were made because an inappropriate ion-to-neutral ratio was used. The ion-to-neutral ratio of the analyte differs subst...
Joachim Wegener
Joachim Wegener
DNA/RNA and protein microarrays have proven their outstanding bioanalytical performance throughout the past decades, given the unprecedented level of parallelization by which molecular recognition assays can be performed and analyzed. Cell ...
Carbohydrates on Proteins: Site-Specific Glycosylation Analysis by Mass Spectrometry [0.03%]
蛋白质上的碳水化合物：通过质谱进行位点特异性糖基化分析
Zhikai Zhu,Heather Desaire
Zhikai Zhu
Glycosylation on proteins adds complexity and versatility to these biologically vital macromolecules. To unveil the structure-function relationship of glycoproteins, glycopeptide-centric analysis using mass spectrometry (MS) has become a me...
Amanda Buchberger,Qing Yu,Lingjun Li
Amanda Buchberger
Neuropeptides are important mediators in the functionality of the brain and other neurological organs. Because neuropeptides exist in a wide range of concentrations, appropriate characterization methods are needed to provide dynamic, chemic...
Nadine Vogler,Sandro Heuke,Thomas W Bocklitz et al.
Nadine Vogler et al.
Advanced optical imaging technologies have experienced increased visibility in medical research, as they allow for a label-free and nondestructive investigation of tissue in either an excised state or living organisms. In addition to a mult...
William D Hoffmann,Glen P Jackson
William D Hoffmann
Developments in forensic mass spectrometry tend to follow, rather than lead, the developments in other disciplines. Examples of techniques having forensic potential born independently of forensic applications include ambient ionization, ima...
Ronny Kirste,Nathaniel Rohrbaugh,Isaac Bryan et al.
Ronny Kirste et al.
We review recent advances of AlGaN/GaN high-electron-mobility transistor (HEMT)-based electronic biosensors. We discuss properties and fabrication of III-nitride-based biosensors. Because of their superior biocompatibility and aqueous stabi...
John R Engen,Thomas E Wales
John R Engen
This article reviews the analytical aspects of measuring hydrogen exchange by mass spectrometry (HX MS). We describe the nature of analytical selectivity in hydrogen exchange, then review the analytical tools required to accomplish fragment...
Richard J Nichols,Simon J Higgins
Richard J Nichols
It is now possible to measure the electrical properties of single molecules using a variety of techniques including scanning probe microcopies and mechanically controlled break junctions. Such measurements can be made across a wide range of...