Shannon Eliuk,Alexander Makarov
Shannon Eliuk
We discuss the evolution of Orbitrap mass spectrometry (MS) from its birth in the late 1990s to its current role as one of the most prominent techniques for MS. The Orbitrap mass analyzer is the first high-performance mass analyzer that emp...
Yong Jin Bae,Myung Soo Kim
Yong Jin Bae
An important recent discovery concerning the fundamentals of matrix-assisted laser desorption/ionization (MALDI) is that the abundance of each ion appearing in a spectrum is fixed, regardless of the experimental condition, when an effective...
Klaus Biemann
Klaus Biemann
I review laboratory research on the development of mass spectrometric methodology for the determination of the structure of natural products of biological and medical interest, which I conducted from 1958 to the end of the twentieth century...
Synthetic Nano- and Micromachines in Analytical Chemistry: Sensing, Migration, Capture, Delivery, and Separation [0.03%]
用于分析化学的合成纳米和微米机：传感、迁移、捕获、输送及分离
Wentao Duan,Wei Wang,Sambeeta Das et al.
Wentao Duan et al.
Synthetic nano- and microscale machines move autonomously in solution or drive fluid flows by converting sources of energy into mechanical work. Their sizes are comparable to analytes (sub-nano- to microscale), and they respond to signals f...
Single-Molecule Investigations of Morphology and Mass Transport Dynamics in Nanostructured Materials [0.03%]
纳米结构材料形貌和质量传递动力学的单分子研究
Daniel A Higgins,Seok Chan Park,Khanh-Hoa Tran-Ba et al.
Daniel A Higgins et al.
Nanostructured materials such as mesoporous metal oxides and phase-separated block copolymers form the basis for new monolith, membrane, and thin film technologies having applications in energy storage, chemical catalysis, and separations. ...
Kevin J Johnson,Susan L Rose-Pehrsson
Kevin J Johnson
Chemical detection in complex environments presents numerous challenges for successful implementation. Arrays of sensors are often implemented for complex chemical sensing tasks, but systematic understanding of how individual sensor respons...
I-Chung Lu,Chuping Lee,Yuan-Tseh Lee et al.
I-Chung Lu et al.
In past studies, mistakes in determining the ionization mechanism in matrix-assisted laser desorption/ionization (MALDI) were made because an inappropriate ion-to-neutral ratio was used. The ion-to-neutral ratio of the analyte differs subst...
Joachim Wegener
Joachim Wegener
DNA/RNA and protein microarrays have proven their outstanding bioanalytical performance throughout the past decades, given the unprecedented level of parallelization by which molecular recognition assays can be performed and analyzed. Cell ...
Carbohydrates on Proteins: Site-Specific Glycosylation Analysis by Mass Spectrometry [0.03%]
蛋白质上的碳水化合物：通过质谱进行位点特异性糖基化分析
Zhikai Zhu,Heather Desaire
Zhikai Zhu
Glycosylation on proteins adds complexity and versatility to these biologically vital macromolecules. To unveil the structure-function relationship of glycoproteins, glycopeptide-centric analysis using mass spectrometry (MS) has become a me...
Amanda Buchberger,Qing Yu,Lingjun Li
Amanda Buchberger
Neuropeptides are important mediators in the functionality of the brain and other neurological organs. Because neuropeptides exist in a wide range of concentrations, appropriate characterization methods are needed to provide dynamic, chemic...