Methods for the Analysis of Protein Phosphorylation-Mediated Cellular Signaling Networks [0.03%]
蛋白质磷酸化介导的细胞信号网络分析方法研究进展
Forest M White,Alejandro Wolf-Yadlin
Forest M White
Protein phosphorylation-mediated cellular signaling networks regulate almost all aspects of cell biology, including the responses to cellular stimulation and environmental alterations. These networks are highly complex and comprise hundreds...
New Functionalities for Paper-Based Sensors Lead to Simplified User Operation, Lower Limits of Detection, and New Applications [0.03%]
新型纸基传感器功能引领简便用户操作、更低检测限及全新应用
Josephine C Cunningham,Paul R DeGregory,Richard M Crooks
Josephine C Cunningham
In the last decade, paper analytical devices (PADs) have evolved into sophisticated yet simple sensors with biological and environmental applications in the developed and developing world. The focus of this review is the technological impro...
Electroanalytical Ventures at Nanoscale Interfaces Between Immiscible Liquids [0.03%]
互不相溶的液界面纳米尺度电化学分析研究新进展
Damien W M Arrigan,Yang Liu
Damien W M Arrigan
Ion transfer at the interface between immiscible electrolyte solutions offers many benefits to analytical chemistry, including the ability to detect nonredox active ionized analytes, to detect ions whose redox electrochemistry is accompanie...
Molecular Plasmonics [0.03%]
分子等离激元学
Andrew J Wilson,Katherine A Willets
Andrew J Wilson
In this review, we survey recent advances in the field of molecular plasmonics beyond the traditional sensing modality. Molecular plasmonics is explored in the context of the complex interaction between plasmon resonances and molecules and ...
Marc Tschofen,Dietmar Knopp,Elizabeth Hood et al.
Marc Tschofen et al.
Plants have emerged as commercially relevant production systems for pharmaceutical and nonpharmaceutical products. Currently, the commercially available nonpharmaceutical products outnumber the medical products of plant molecular farming, r...
Proteogenomics: Integrating Next-Generation Sequencing and Mass Spectrometry to Characterize Human Proteomic Variation [0.03%]
蛋白质组基因组学：结合下一代测序与质谱技术以表征人类蛋白质变异特征
Gloria M Sheynkman,Michael R Shortreed,Anthony J Cesnik et al.
Gloria M Sheynkman et al.
Mass spectrometry-based proteomics has emerged as the leading method for detection, quantification, and characterization of proteins. Nearly all proteomic workflows rely on proteomic databases to identify peptides and proteins, but these da...
Advances in Magnetic Resonance Imaging Contrast Agents for Biomarker Detection [0.03%]
磁共振成像造影剂在生物标记物检测中的应用进展
Sanhita Sinharay,Mark D Pagel
Sanhita Sinharay
Recent advances in magnetic resonance imaging (MRI) contrast agents have provided new capabilities for biomarker detection through molecular imaging. MRI contrast agents based on the T2 exchange mechanism have more recently expanded the arm...
James H Wade,Ryan C Bailey
James H Wade
Optical resonator sensors are an emerging class of analytical technologies that use recirculating light confined within a microcavity to sensitively measure the surrounding environment. Bolstered by advances in microfabrication, these devic...
Mass Spectrometry Applied to Bottom-Up Proteomics: Entering the High-Throughput Era for Hypothesis Testing [0.03%]
质谱在从上到下蛋白质组学中的应用：进入用于假设检验的高效时代
Ludovic C Gillet,Alexander Leitner,Ruedi Aebersold
Ludovic C Gillet
Proteins constitute a key class of molecular components that perform essential biochemical reactions in living cells. Whether the aim is to extensively characterize a given protein or to perform high-throughput qualitative and quantitative ...
Real-Time Monitoring of Critical Care Analytes in the Bloodstream with Chemical Sensors: Progress and Challenges [0.03%]
化学传感器实时监测血液危重病生化指标的进展和挑战
Megan C Frost,Mark E Meyerhoff
Megan C Frost
We review approaches and challenges in developing chemical sensor-based methods to accurately and continuously monitor levels of key analytes in blood related directly to the status of critically ill hospitalized patients. Electrochemical a...