R Graham Cooks,Xin Yan
R Graham Cooks
Mass spectrometry is the science and technology of ions. As such, it is concerned with generating ions, measuring their properties, following their reactions, isolating them, and using them to build and transform materials. Instrumentation ...
Shudong Zhang,Mingzhi Li,Bin Su et al.
Shudong Zhang et al.
This review summarizes progress in the fabrication, modification, characterization, and applications of nanopipettes since 2010. A brief history of nanopipettes is introduced, and the details of fabrication, modification, and characterizati...
Relative and Absolute Quantitation in Mass Spectrometry-Based Proteomics [0.03%]
基于质谱的蛋白质组学中的相对和绝对定量
J Astor Ankney,Adil Muneer,Xian Chen
J Astor Ankney
Mass spectrometry-based quantitative proteomics is a powerful tool for gaining insights into function and dynamics of biological systems. However, peptides with different sequences have different ionization efficiencies, and their intensiti...
Johannes Thoma,K Tanuj Sapra,Daniel J Müller
Johannes Thoma
Single-molecule force spectroscopy (SMFS) has been widely applied to study the mechanical unfolding and folding of transmembrane proteins. Here, we review the recent progress in characterizing bacterial and human transmembrane β-barrel pro...
Improving Lateral Flow Assay Performance Using Computational Modeling [0.03%]
基于计算模型的 lateral flow assay 性能改进研究
David Gasperino,Ted Baughman,Helen V Hsieh et al.
David Gasperino et al.
The performance, field utility, and low cost of lateral flow assays (LFAs) have driven a tremendous shift in global health care practices by enabling diagnostic testing in previously unserved settings. This success has motivated the continu...
Kaiyan Qiu,Ghazaleh Haghiashtiani,Michael C McAlpine
Kaiyan Qiu
Medical errors are a major concern in clinical practice, suggesting the need for advanced surgical aids for preoperative planning and rehearsal. Conventionally, CT and MRI scans, as well as 3D visualization techniques, have been utilized as...
Boron Doped Diamond: A Designer Electrode Material for the Twenty-First Century [0.03%]
掺硼金刚石：二十一世纪的“定制化”电极材料
Samuel J Cobb,Zoe J Ayres,Julie V Macpherson
Samuel J Cobb
Boron doped diamond (BDD) is continuing to find numerous electrochemical applications across a diverse range of fields due to its unique properties, such as having a wide solvent window, low capacitance, and reduced resistance to fouling an...
Analytical Chemistry in the Regulatory Science of Medical Devices [0.03%]
体外诊断医疗器械监管 science中分析化学的作用与发展
Yi Wang,Allan Guan,Samanthi Wickramasekara et al.
Yi Wang et al.
In the United States, regulatory science is the science of developing new tools, standards, and approaches to assess the safety, efficacy, quality, and performance of all Food and Drug Administration-regulated products. Good regulatory scie...
Interfacing Cells with Vertical Nanoscale Devices: Applications and Characterization [0.03%]
细胞与垂直纳米设备接口：应用和表征
Allister F McGuire,Francesca Santoro,Bianxiao Cui
Allister F McGuire
Measurements of the intracellular state of mammalian cells often require probes or molecules to breach the tightly regulated cell membrane. Mammalian cells have been shown to grow well on vertical nanoscale structures in vitro, going out of...
Voltammetric Perspectives on the Acidity Scale and H+/H2 Process in Ionic Liquid Media [0.03%]
离子液体介质中的酸度标度和H+/H2过程的伏安视角
Cameron L Bentley,Alan M Bond,Jie Zhang
Cameron L Bentley
Nonhaloaluminate ionic liquids (ILs) have received considerable attention as alternatives to molecular solvents in diverse applications spanning the fields of physical, chemical, and biological science. One important and often overlooked as...